@pipeworx/gtex

GTEx Portal MCP — Genotype-Tissue Expression: human gene expression across ~54 tissues. Keyless.

Part of Pipeworx — an MCP gateway connecting AI agents to 1394+ live data sources.

Tools

• gene(gencode_id_or_symbol) — gene metadata

• median_expression(gene) — median expression across tissues

• top_expressed_genes(tissue, filter_mt_gene?, num?, datasetId?) — top-expressed genes per tissue

• single_tissue_eqtls(gencode_id, tissue?) — significant single-tissue eQTLs

• tissues() — list of tissues

Related MCP server: clingen-link

Data source

https://gtexportal.org/api/v2/

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "gtex": {
      "url": "https://gateway.pipeworx.io/gtex/mcp"
    }
  }
}

Or connect to the full Pipeworx gateway for access to all 1394+ data sources:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English:

ask_pipeworx({ question: "your question about Gtex data" })

The gateway picks the right tool and fills the arguments automatically.

More

• Docs and guides

• pipeworx.io

License

MIT