vep_region_batch
Annotate multiple variants in batch using genomic coordinates. Returns effect predictions, conservation, and pathogenicity scores for specified species.
Instructions
Annotate multiple variants using genomic coordinates in batch
Input Schema
TableJSON Schema
| Name | Required | Description | Default |
|---|---|---|---|
| species | Yes | Species name (e.g., 'homo_sapiens', 'mus_musculus') | homo_sapiens |
| regions | Yes | List of variants in VCF format (e.g., ['1 230710048 . A G', '9 22125504 . G C']). Format: 'CHR POS ID REF ALT' where CHR=chromosome, POS=position, ID=identifier (use '.' if unknown), REF=reference allele, ALT=alternate allele. | |
| canonical | No | Include only canonical transcripts per gene | |
| hgvs | No | Include HGVS nomenclature | |
| domains | No | Include protein domain information | |
| ccds | No | Include CCDS transcript identifiers | |
| protein | No | Include protein sequence identifiers | |
| AlphaMissense | No | Include AlphaMissense pathogenicity scores | |
| CADD | No | Include CADD deleteriousness scores | |
| REVEL | No | Include REVEL pathogenicity scores | |
| Conservation | No | Include conservation scores |