Clinical Intelligence MCP Server - MVP 1

What this MVP includes

• ClinicalTrials.gov v2 search

• PubMed search via NCBI E-utilities

• Open Targets target lookup

• openFDA regulatory context

• Optional Vertex AI Google Search grounding

• FastMCP over Streamable HTTP for LibreChat

Related MCP server: Medical Research MCP Suite

Local setup

python -m venv .venv
source .venv/bin/activate   # Windows: .venv\Scripts\activate
pip install -r requirements.txt
cp .env.example .env
uvicorn app.main:app --reload --host 0.0.0.0 --port 8000

Health checks

curl http://localhost:8000/health
curl http://localhost:8000/health/sources

MCP endpoint

Useful test URLs

curl "http://localhost:8000/health/sources"

Pytest

pytest -q

Vertex AI Google Search grounding

This is optional.

Set:

GOOGLE_CLOUD_PROJECT GOOGLE_CLOUD_LOCATION=global ENABLE_VERTEX_WEB_SEARCH=true

Also ensure your environment has Google Cloud credentials available.

If this is disabled, the rest of the server still works.