STRING MCP Server

Model Context Protocol (MCP) server providing access to the STRING protein-protein interaction database.

Features

9 tools for protein interaction analysis:

• Mapping protein identifiers to STRING IDs

• Retrieving protein interaction networks

• Finding interaction partners

• Functional enrichment analysis (GO, KEGG, pathways)

• PPI enrichment testing

• Cross-species homology mapping

• Protein name resolution

Full endpoint documentation available in ENDPOINTS.md.

Related MCP server: UniProt MCP Server

Installation

From GitHub

npm install git+https://github.com/munch-group/string-mcp.git
cd node_modules/string-mcp
npm run build

From source

git clone https://github.com/munch-group/string-mcp.git
cd string-mcp
npm install
npm run build

Usage with Claude Desktop

# Using built version
claude mcp add string node /path/to/string-mcp/build/index.js

# Or from npm global install
claude mcp add string npx -y string-mcp

Configuration

Add to your Claude Desktop config:

{
  "mcpServers": {
    "string": {
      "command": "node",
      "args": ["/path/to/string-mcp/build/index.js"]
    }
  }
}

Common Species Taxon IDs

• Human: 9606

• Mouse: 10090

• Rat: 10116

• Fruit fly: 7227

• C. elegans: 6239

• Yeast: 4932

Building

npm run build

Dependencies

• @mcp/rest-utils - Shared REST utilities

• @modelcontextprotocol/sdk - MCP SDK

• zod - Schema validation

License

ISC