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get_homology

Find homologous genes or proteins across species using Ensembl data to identify evolutionary relationships and functional equivalents.

Instructions

Get homologous genes/proteins across species

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
idYesEnsembl gene stable ID
speciesNoSpecies name for the genehuman
target_speciesNoTarget species for homology search (optional)
typeNoType of homologyorthologues
Behavior2/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

With no annotations provided, the description carries the full burden of behavioral disclosure. It states the tool retrieves homology data but lacks details on permissions, rate limits, data sources, or response format. This is insufficient for a tool with potential complexity in biological data retrieval.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is a single, efficient sentence that directly states the tool's function without unnecessary words. It is front-loaded and earns its place by clearly conveying the core purpose.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness3/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given the tool's moderate complexity (4 parameters, no output schema, no annotations), the description is minimally adequate. It covers the basic purpose but lacks behavioral context and usage guidance, leaving gaps for an AI agent to infer proper invocation.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, so the schema fully documents all parameters. The description adds no additional meaning beyond the schema, such as explaining homology types or species naming conventions. Baseline 3 is appropriate as the schema handles parameter documentation adequately.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the tool's purpose: retrieving homologous genes/proteins across species. It specifies the resource (genes/proteins) and the operation (get homologous ones), but doesn't distinguish this from sibling tools like get_ontology_ancestors or get_sequence, which serve different biological queries.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines2/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

No guidance is provided on when to use this tool versus alternatives. While the description implies it's for homology searches, it doesn't specify scenarios, prerequisites, or exclusions, such as when to prefer this over other gene-related tools like get_xrefs_by_gene or lookup_gene_by_id.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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