leiden

Instructions

Tool call template

This tool declares no required parameters. Add optional parameters from the input schema as needed.

{
  "id": 1,
  "jsonrpc": "2.0",
  "method": "tools/call",
  "params": {
    "arguments": {},
    "name": "leiden"
  }
}

Implementation Reference

• src/scmcp/tool/tl.py:47-52 (registration)

  MCP tool registration for 'leiden' with name, description, and schema reference.

  # Add leiden tool
  leiden_tool = types.Tool(
      name="leiden",
      description="Leiden clustering algorithm for community detection",
      inputSchema=LeidenModel.model_json_schema(),
  )

• src/scmcp/schema/tl.py:267-342 (schema)

  Pydantic model defining input schema and validation for leiden tool parameters.

  class LeidenModel(JSONParsingModel):
      """Input schema for the Leiden clustering algorithm."""
      
      resolution: float = Field(
          default=1.0,
          description="A parameter value controlling the coarseness of the clustering. Higher values lead to more clusters."
      )
      
      random_state: int = Field(
          default=0,
          description="Change the initialization of the optimization."
      )
      
      key_added: str = Field(
          default='leiden',
          description="`adata.obs` key under which to add the cluster labels."
      )
      
      directed: Optional[bool] = Field(
          default=None,
          description="Whether to treat the graph as directed or undirected."
      )
      
      use_weights: bool = Field(
          default=True,
          description="If `True`, edge weights from the graph are used in the computation (placing more emphasis on stronger edges)."
      )
      
      n_iterations: int = Field(
          default=-1,
          description="How many iterations of the Leiden clustering algorithm to perform. -1 runs until optimal clustering."
      )
      
      neighbors_key: Optional[str] = Field(
          default=None,
          description="Use neighbors connectivities as adjacency. If specified, leiden looks .obsp[.uns[neighbors_key]['connectivities_key']] for connectivities."
      )
      
      obsp: Optional[str] = Field(
          default=None,
          description="Use .obsp[obsp] as adjacency. You can't specify both `obsp` and `neighbors_key` at the same time."
      )
      
      flavor: Literal['leidenalg', 'igraph'] = Field(
          default='igraph',
          description="Which package's implementation to use."
      )
      
      clustering_args: Optional[Dict[str, Any]] = Field(
          default=None,
          description="Any further arguments to pass to the clustering algorithm."
      )
      
      @field_validator('resolution')
      def validate_resolution(cls, v: float) -> float:
          """Validate resolution is positive"""
          if v <= 0:
              raise ValueError("resolution must be a positive number")
          return v
      
      @field_validator('obsp', 'neighbors_key')
      def validate_graph_source(cls, v: Optional[str], info: ValidationInfo) -> Optional[str]:
          """Validate that obsp and neighbors_key are not both specified"""
          values = info.data
          if v is not None and 'obsp' in values and 'neighbors_key' in values:
              if values['obsp'] is not None and values['neighbors_key'] is not None:
                  raise ValueError("Cannot specify both obsp and neighbors_key")
          return v
      
      @field_validator('flavor')
      def validate_flavor(cls, v: str) -> str:
          """Validate flavor is supported"""
          if v not in ['leidenalg', 'igraph']:
              raise ValueError("flavor must be either 'leidenalg' or 'igraph'")
          return v

• src/scmcp/tool/tl.py:164-177 (handler)

  Generic execution handler for tl tools including 'leiden'; resolves sc.tl.leiden from tl_func dict, validates parameters via signature, executes on active adata, and logs operation.

  def run_tl_func(ads, func, arguments):
      adata = ads.adata_dic[ads.active]
      if func not in tl_func:
          raise ValueError(f"Unsupported function: {func}")
      run_func = tl_func[func]
      parameters = inspect.signature(run_func).parameters
      kwargs = {k: arguments.get(k) for k in parameters if k in arguments}    
      try:
          res = run_func(adata, **kwargs)
          add_op_log(adata, run_func, kwargs)
      except Exception as e:
          logger.error(f"Error running function {func}: {e}")
          raise
      return 

• src/scmcp/tool/tl.py:125-142 (helper)

  Mapping dictionary tl_func that associates 'leiden' tool name with scanpy.tl.leiden function for execution.

  tl_func = {
      "tsne": sc.tl.tsne,
      "umap": sc.tl.umap,
      "draw_graph": sc.tl.draw_graph,
      "diffmap": sc.tl.diffmap,
      "embedding_density": sc.tl.embedding_density,
      "leiden": sc.tl.leiden,
      "louvain": sc.tl.louvain,
      "dendrogram": sc.tl.dendrogram,
      "dpt": sc.tl.dpt,
      "paga": sc.tl.paga,
      "ingest": sc.tl.ingest,
      "rank_genes_groups": sc.tl.rank_genes_groups,
      "filter_rank_genes_groups": sc.tl.filter_rank_genes_groups,
      "marker_gene_overlap": sc.tl.marker_gene_overlap,
      "score_genes": sc.tl.score_genes,
      "score_genes_cell_cycle": sc.tl.score_genes_cell_cycle,
  }

• src/scmcp/tool/tl.py:145-162 (helper)

  tl_tools dictionary that includes the 'leiden' tool object for listing and dispatch.

  tl_tools = {
      "tsne": tsne_tool,
      "umap": umap_tool,
      "draw_graph": draw_graph_tool,
      "diffmap": diffmap_tool,
      "embedding_density": embedding_density_tool,
      "leiden": leiden_tool,
      "louvain": louvain_tool,
      "dendrogram": dendrogram_tool,
      "dpt": dpt_tool,
      "paga": paga_tool,
      "ingest": ingest_tool,
      "rank_genes_groups": rank_genes_groups_tool,
      "filter_rank_genes_groups": filter_rank_genes_groups_tool,
      "marker_gene_overlap": marker_gene_overlap_tool,
      "score_genes": score_genes_tool,
      "score_genes_cell_cycle": score_genes_cell_cycle_tool,
  }