Cutaneous Microdialysis Perfusion Recovery Skill
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Cutaneous Microdialysis Perfusion Recovery Skill
Cutaneous Microdialysis In Vivo Relative Recovery and Zero-Net-Flux (ZNF) Quantitative Analyzer based on Bungay transport modeling.
flowchart TD
A[Variable Perfusate Concentrations C_in] --> B[Collect Dialysate Concentrations C_out]
B --> C[Compute Net Membrane Flux: Delta C = C_in - C_out]
C --> D[Linear Regression: Delta C vs C_in]
D --> E[Zero-Net-Flux Point: Delta C = 0 -> True C_interstitial]
D --> F[Slope = In Vivo Probe Extraction Fraction E_d]
E & F --> G[Biomarker Quantitation & Probe Delivery Guidance]Features
Zero PIP Dependencies: Implemented strictly with Python Standard Library (
math,json,sys,typing).Zero-Net-Flux Method: Determines exact interstitial concentrations independent of unknown tissue tortuosity or probe fouling.
Bungay Transport Physics: Validated against classic in vivo microdialysis mass-transfer equations.
Dual Architecture: Native Python import and Model Context Protocol (MCP) JSON-RPC 2.0 stdio server.
Related MCP server: cutaneous-microcirculation
Quickstart
python example_usage.pyLicense
Apache-2.0
This server cannot be deployed
Maintenance
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