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build_pbpk_context_bundle

build_pbpk_context_bundle
Read-onlyIdempotent

Build a CompTox PBPK context bundle from HTTK, ADME/IVIVE, exposure hints, and model-card references for a chemical to support toxicokinetic modeling.

Instructions

Build a CompTox-side PBPK context bundle from HTTK, ADME/IVIVE, exposure hints, and model-card references.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
dtxsidNoDSSTox substance identifier to summarize.
identifierNoOptional non-DTXSID identifier to resolve before building the bundle.
model_nameNoOptional model-card name filter.
allow_fallbackNo
max_candidatesNo
identifier_typeNoOptional identifier category when `identifier` is supplied.

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
dataNo
metadataNo
httkSliceYes
provenanceYes
limitationsNo
exposureHintsYes
handoffTargetYes
knownDataGapsNo
modelCardRefsYes
provenanceSummaryNo
generatedFromToolsNo
identityResolutionNo
chemicalIdentityRefYes
hazardAdmeIviveSliceYes

Schema Changelog

Changes observed during successful MCP inspections.

  1. First observedv0.3.0

TDQS

B3/5.0
Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnlyHint, idempotentHint, openWorldHint and destructiveHint=false, so the safety profile is covered. The description usefully names the aggregation sources, but says nothing about the meaning of allow_fallback (does it degrade the bundle?), latency, or what 'context bundle' contains.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

One front-loaded sentence that wastes no words and puts the resource and sources up front. It is efficient, though it reads as a flat list rather than prioritizing the key constraint.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness3/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

An output schema exists, so return values need no explanation, and the annotations cover safety. However, for a 6-parameter aggregation tool with a fallback switch and moderate schema coverage, missing when-to-use and fallback semantics leave real gaps.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters2/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema coverage is only 67%, and the two undocumented parameters (allow_fallback, max_candidates) are not explained in the description either. 'model-card references' loosely hints at model_name, but the fallback and candidate-limit semantics that govern behavior are left entirely opaque.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

States a specific verb ('Build') and resource ('CompTox-side PBPK context bundle') and enumerates the source domains (HTTK, ADME/IVIVE, exposure, model cards). It is clear what the tool produces, but it does not distinguish itself from the similar-sounding sibling assemble_comptox_evidence_pack.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines2/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

No guidance on when to use this aggregation tool rather than the adjacent assemble_comptox_evidence_pack, nor on prerequisites (resolvable identifier, DTXSID requirement). The agent must infer the context entirely from the name.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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