evo2_batch_score
Score multiple single-nucleotide variants against one wildtype sequence in a single batch, reusing the wildtype forward pass and reporting per-variant errors for saturation-mutagenesis analyses.
Instructions
Score many single-nucleotide variants against one wildtype sequence. The WT forward pass is computed exactly once and reused; identical (position, alt) mutants are forwarded once; mutant requests run with bounded concurrency (EVO2_MCP_MAX_CONCURRENCY, default 2) to respect NVIDIA rate limits, and per-variant API errors are reported per-variant. Use for saturation-mutagenesis-style analyses. This is a DNA foundation model inference tool. It does not provide clinical diagnosis. Model scores should not be interpreted as pathogenicity labels without additional validation.
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| sequence | Yes | Wildtype DNA sequence (>= 2 bp). | |
| variants | Yes | List of {position, ref, alt} dicts (1-based positions). | |
| coordinate | No | 1-based |