seosiri-bioassay-mcp

An open-source, local-first Model Context Protocol (MCP) server for High-Throughput Screening (HTS) assay calculations spanning Sub-Cellular, Cellular, Tissue, and Organism biological tiers.

💖 Sponsorship, B2B Custom Solutions & Attribution

👨‍💻 Lead Architect & Attribution

Designed and engineered by Momenul Ahmad, Lead Architect and Founder of SEOSiri.

🚀 Supported Biological Segments & Assays

• Sub-Cellular: TR-FRET ratio analysis for PROTAC (BRD4/CRBN), KRAS (G12C), receptor binding, and HICA ultra-sensitive protein assays.

• Cellular: UA-Glo luminescent screening for 2D/3D cell viability, Caspase 3/7 apoptosis, kinase activity, and reporter gene systems (NF-kB/Wnt).

• Tissue: 3D spheroid/organoid drug penetration depth and tissue slice barrier diffusion models.

• Organism: In vivo animal model pharmacokinetics ($C_{\max}$, AUC, half-life, plasma concentration decay).

Related MCP server: BioMCP

Quickstart

pip install -e .
pytest tests/test_bioassay.py

🔌 Claude Desktop / Cursor Setup

Add this configuration to claude_desktop_config.json:

{
  "mcpServers": {
    "seosiri-bioassay": {
      "command": "uv",
      "args": [
        "run",
        "--github",
        "SEOSiri-Official/bioassay-mcp",
        "src/main_server.py"
      ]
    }
  }
}

License

Distributed under the MIT License. See LICENSE for details.