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get_homology_best

Find best homology matches for proteins across species in the STRING database to identify evolutionary relationships and functional similarities.

Instructions

Get best homology matches for proteins.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
identifiersYesProtein list
speciesNoSource species NCBI/STRING taxon
species_bNoTarget species list for homology search
Behavior2/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

With no annotations provided, the description carries the full burden of behavioral disclosure. It states the tool retrieves matches but doesn't describe what 'best' entails (e.g., criteria like score thresholds), output format, rate limits, or error handling. This is inadequate for a tool with parameters and no output schema.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is a single, efficient sentence with no wasted words. It is front-loaded with the core purpose, making it easy to parse quickly. Every word earns its place in conveying the essential function.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness2/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given the complexity of homology matching, 3 parameters, no annotations, and no output schema, the description is incomplete. It lacks details on behavior, output, and usage context, leaving significant gaps for an agent to understand how to effectively invoke and interpret results.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, so the schema fully documents parameters (identifiers, species, species_b). The description adds no additional meaning beyond implying homology matching, which is already inferred from the tool name. Baseline 3 is appropriate as the schema does the heavy lifting.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the action ('Get') and target resource ('best homology matches for proteins'), making the purpose immediately understandable. It distinguishes from the sibling 'get_homology' by specifying 'best' matches, though it doesn't fully explain what makes them 'best' versus the sibling's approach.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines2/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

No guidance is provided on when to use this tool versus alternatives like 'get_homology' or other sibling tools. The description lacks context about use cases, prerequisites, or exclusions, leaving the agent without direction on tool selection.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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