Bio-OS MCP Server
# Bio-OS MCP Server
A Model Context Protocol (MCP) based tool and prompt server for Bio-OS that provides workflow management and Docker image building capabilities.
## Usage
We recommend using the CLINE extension for VSCode to interact with this MCP tool. There are two deployment options available: standalone installation on your local machine or using Code Server in a Miracle Cloud IES instance. Choose the option that best suits your needs.
### Local Installation (Using MCP through local VSCode)
#### Prerequisites
Bio-OS MCP Server requires the following dependencies:
1. Install uv (Python package manager):
```bash
pip install uv
```
2. Install Cromwell (Workflow execution engine):
```bash
brew install cromwell
```
#### Installation
Clone the Bio-OS MCP Server repository:
```bash
git clone https://github.com/GBA-BI/bioos-mcp-server.git
```
#### Configuration
Configure the Bio-OS MCP Server script path in CLINE's MCP settings. Replace the placeholders with absolute paths to your installation:
```json
{
"mcpServers": {
"bioos": {
"command": "path/to/uv",
"args": [
"--directory",
"path/to/bioos-mcp-server",
"run",
"path/to/bioos-mcp-server/src/bioos_mcp/bioos_mcp_server.py"
],
"env": {
"PYTHONPATH": "path/to/bioos-mcp-server/src",
"MIRACLE_ACCESS_KEY": "xxxxxxxxxxxx",
"MIRACLE_SECRET_KEY": "xxxxxxxxxxxx"
}
}
}
}
```
Follow the configuration process shown below. The Bio-OS MCP Server is ready to use when the status turns green. If the connection is unstable, click "Retry Connection":

Since CLINE does not yet support MCP Prompts, copy the contents of `bioos-mcp-prompt.md` into CLINE's Custom Instructions for optimal experience:

After completing the configuration, you can begin using the Bio-OS MCP Server for development.
### Cloud Installation (Using MCP through Code Server in Miracle Cloud)
For Miracle Cloud users, we provide a pre-configured Docker image with all Bio-OS MCP Server dependencies. Follow these steps:
1. Launch an IES instance using the image: `registry-vpc.miracle.ac.cn/infcprelease/iespro:250217`
2. Select "Open with VSCode" to access the development environment:


#### Configuration in Code Server
1. Click the CLINE icon in the left sidebar and configure your LLM model credentials:

2. Navigate to CLINE's MCP configuration page and verify that Bio-OS MCP Server is properly connected. Use "Retry Connection" if needed:

Once configured, you can begin development with Bio-OS MCP Server.
## Features
### 1. Workflow Management
- Submit and monitor workflows
- Upload WDL workflows
- Validate WDL scripts
- Generate input file templates
### 2. Docker Image Management
- Build Docker images
- Check build status
- Monitor build progress
- Retrieve build logs
## API Reference
### Tools
1. `submit_workflow`
- Function: Submit Bio-OS workflow
- Parameters:
- ak: Access Key
- sk: Secret Key
- workspace_name: Workspace name
- workflow_name: Workflow name
- input_json: Input JSON file path
2. `import_workflow`
- Function: Upload WDL workflow to Bio-OS system
- Parameters:
- ak: Access Key
- sk: Secret Key
- workspace_name: Workspace name
- workflow_name: Workflow name
- workflow_source: WDL file path
- workflow_desc: Workflow description
3. `validate_wdl`
- Function: Validate WDL workflow script
- Parameters:
- wdl_path: WDL file path
4. `generate_inputs`
- Function: Generate WDL input file template
- Parameters:
- wdl_path: WDL file path
5. `build_docker_image`
- Function: Build Docker image
- Parameters:
- registry: Image registry address
- namespace_name: Namespace
- repo_name: Repository name
- tag: Version tag
- source_path: Dockerfile or archive path
6. `check_build_status`
- Function: Check Docker image build status
- Parameters:
- task_id: Build task ID
### Prompts (Not supported in Cline yet)
1. `wdl_development_workflow_prompt`
- Function: Generate complete guidance for WDL workflow development
- Content:
- WDL script development steps
- Task structure guidelines
- Runtime configuration requirements
- Docker image preparation guide
2. `wdl_runtime_prompt`
- Function: Generate WDL runtime configuration template
- Content:
- Required docker image configuration
- Memory settings (default: 8 GB)
- Disk settings (default: 20 GB)
- CPU settings (default: 4)
3. `workflow_input_prompt`
- Function: Generate workflow input preparation guide
- Content:
- Input file preparation steps
- Parameter validation guidelines
- File path requirements
4. `workflow_submission_prompt`
- Function: Generate workflow submission template
- Content:
- Required credentials (ak/sk)
- Workspace configuration
- Input file requirements
5. `docker_build_prompt`
- Function: Generate Docker build process guide
- Content:
- Dockerfile generation steps
- Build configuration requirements
- Image registry settings
- Build status monitoring guide
Note: Prompts are currently not supported in Cline environment. These prompts are only available when using the MCP server directly or through Claude Desktop.
## ✅ Certified by MCPHub
[](https://mcphub.com/mcp-servers/GBA-BI/bioos-mcp-server)
This server is officially certified by [MCPHub](https://mcphub.com/mcp-servers/GBA-BI/bioos-mcp-server). Verify certification status on our MCPHub profile page.
## Contributing
Issues and Pull Requests are welcome.
## License
MIT LicenseTDQS
Scored across 22 tools
Most tools have distinct purposes, but there is some overlap between 'check_workflow_import_status' and 'check_workflow_run_status' which could cause confusion in monitoring workflows. Additionally, 'compose_input_json' and 'generate_inputs_json_template_bioos' both handle input JSON generation, though their descriptions suggest different contexts (user-provided values vs. template generation). Overall, the tools are well-differentiated, but a few pairs require careful reading to avoid misselection.
The naming follows a mostly consistent verb_noun pattern (e.g., 'build_docker_image', 'create_workspace_bioos'), but there are deviations such as 'fetch_wdl_from_dockstore' (verb_noun_preposition) and mixed use of underscores with terms like 'Bio-OS' in names (e.g., 'export_bioos_workspace'). While readable, the lack of a strict convention across all tools reduces predictability.
With 22 tools, the count is on the higher side but reasonable for a comprehensive bioinformatics platform covering Docker builds, workspace management, workflow handling, and IES instances. It feels slightly heavy but not excessive, as each tool appears to serve a specific function in the domain without obvious redundancy.
The tool set provides complete coverage for the bioinformatics domain, including CRUD operations for workspaces and IES instances, workflow lifecycle management (import, validate, submit, monitor, delete), and supporting utilities like Docker image handling and input generation. No significant gaps are apparent; agents can perform end-to-end tasks without dead ends.