Clinical Trials MCP Server

Instructions

Implementation Reference

• src/index.ts:1250-1315 (handler)

  The `handleSearchBySponsor` method implements the logic for the `search_by_sponsor` tool. It takes `sponsor` and `sponsorType` as arguments and queries the ClinicalTrials.gov API.

  private async handleSearchBySponsor(args: any) {
    if (!args?.sponsor) {
      throw new McpError(
        ErrorCode.InvalidParams,
        "Sponsor parameter is required"
      );
    }
  
    const params: any = {
      format: "json",
      pageSize: args?.pageSize || 10,
      "query.spons": args.sponsor,
    };
  
    if (args?.sponsorType) {
      params["filter.leadSponsorClass"] = args.sponsorType;
    }
  
    try {
      const response: AxiosResponse<StudySearchResponse> =
        await this.axiosInstance.get("/studies", { params });
  
      const studies = response.data.studies || [];
      const results = studies.map((study) => ({
        ...this.formatStudySummary(study),
        sponsorDetails:
          study.protocolSection.sponsorCollaboratorsModule?.leadSponsor,
      }));
  
      return {
        content: [
          {
            type: "text",
            text: JSON.stringify(
              {
                searchCriteria: {
                  sponsor: args.sponsor,
                  sponsorType: args.sponsorType,
                },
                totalCount: response.data.totalCount || 0,
                resultsShown: results.length,
                studies: results,
              },
              null,
              2
            ),
          },
        ],
      };
    } catch (error) {
      if (axios.isAxiosError(error)) {
        return {
          content: [
            {
              type: "text",
              text: `Clinical Trials API error: ${
                error.response?.data?.message || error.message
              }`,
            },
          ],
          isError: true,
        };
      }
      throw error;
    }
  }

• src/index.ts:300-326 (registration)

  The tool `search_by_sponsor` is registered within the `ListToolsRequestSchema` handler in `src/index.ts`. It takes a `sponsor` string and optional `sponsorType` and `pageSize` arguments.

    name: "search_by_sponsor",
    description: "Search clinical trials by sponsor or organization",
    inputSchema: {
      type: "object",
      properties: {
        sponsor: {
          type: "string",
          description:
            'Sponsor name or organization (e.g., "Pfizer", "National Cancer Institute")',
          minLength: 2,
        },
        sponsorType: {
          type: "string",
          description: "Type of sponsor",
          enum: ["INDUSTRY", "NIH", "FED", "OTHER"],
        },
        pageSize: {
          type: "number",
          description:
            "Number of results to return (default 10, max 100)",
          minimum: 1,
          maximum: 100,
        },
      },
      required: ["sponsor"],
    },
  },