Clinical Trials MCP Server

Instructions

Implementation Reference

• build/index.js:841-903 (handler)

  Implementation of the search_by_condition tool handler.

  async handleSearchByCondition(args) {
      if (!args?.condition) {
          throw new McpError(ErrorCode.InvalidParams, "Condition parameter is required");
      }
      const params = {
          format: "json",
          pageSize: args?.pageSize || 10,
          "query.cond": args.condition,
      };
      if (args?.phase) {
          params["filter.phase"] = args.phase;
      }
      if (args?.recruitmentStatus) {
          params["filter.overallStatus"] = args.recruitmentStatus;
      }
      try {
          const response = await this.axiosInstance.get("/studies", { params });
          const studies = response.data.studies || [];
          const results = studies.map((study) => ({
              ...this.formatStudySummary(study),
              conditions: study.protocolSection.conditionsModule?.conditions || [],
              eligibility: {
                  sex: study.protocolSection.eligibilityModule?.sex || "Unknown",
                  minimumAge: study.protocolSection.eligibilityModule?.minimumAge ||
                      "Not specified",
                  maximumAge: study.protocolSection.eligibilityModule?.maximumAge ||
                      "Not specified",
                  healthyVolunteers: study.protocolSection.eligibilityModule?.healthyVolunteers || false,
              },
          }));
          return {
              content: [
                  {
                      type: "text",
                      text: JSON.stringify({
                          searchCriteria: {
                              condition: args.condition,
                              phase: args.phase,
                              recruitmentStatus: args.recruitmentStatus,
                          },
                          totalCount: response.data.totalCount || 0,
                          resultsShown: results.length,
                          studies: results,
                      }, null, 2),
                  },
              ],
          };
      }
      catch (error) {
          if (axios.isAxiosError(error)) {
              return {
                  content: [
                      {
                          type: "text",
                          text: `Clinical Trials API error: ${error.response?.data?.message || error.message}`,
                      },
                  ],
                  isError: true,
              };
          }
          throw error;
      }
  }

• build/index.js:159-192 (registration)

  Tool registration and schema definition for search_by_condition in the ListToolsRequest handler.

      name: "search_by_condition",
      description: "Search for clinical trials focusing on specific medical conditions",
      inputSchema: {
          type: "object",
          properties: {
              condition: {
                  type: "string",
                  description: "Medical condition, disease, or syndrome",
                  minLength: 2,
              },
              phase: {
                  type: "string",
                  description: "Study phase filter",
                  enum: ["PHASE1", "PHASE2", "PHASE3", "PHASE4", "NA"],
              },
              recruitmentStatus: {
                  type: "string",
                  description: "Filter by recruitment status",
                  enum: [
                      "RECRUITING",
                      "NOT_YET_RECRUITING",
                      "ACTIVE_NOT_RECRUITING",
                  ],
              },
              pageSize: {
                  type: "number",
                  description: "Number of results to return (default 10, max 100)",
                  minimum: 1,
                  maximum: 100,
              },
          },
          required: ["condition"],
      },
  },