Clinical Trials MCP Server

Instructions

Implementation Reference

• src/index.ts:1551-1622 (handler)

  Handler function for the 'get_studies_with_results' tool, which fetches completed trials with results from the ClinicalTrials.gov API.

  private async handleGetStudiesWithResults(args: any) {
    const params: any = {
      format: "json",
      pageSize: args?.pageSize || 10,
      "filter.overallStatus": "COMPLETED",
      "filter.hasResults": true,
    };
  
    if (args?.condition) {
      params["query.cond"] = args.condition;
    }
  
    if (args?.intervention) {
      params["query.intr"] = args.intervention;
    }
  
    if (args?.completedAfter) {
      params["filter.primaryCompletionDateFrom"] = args.completedAfter;
    }
  
    try {
      const response: AxiosResponse<StudySearchResponse> =
        await this.axiosInstance.get("/studies", { params });
  
      const studies = response.data.studies || [];
      const results = studies.map((study) => ({
        ...this.formatStudySummary(study),
        completionDate:
          study.protocolSection.statusModule.primaryCompletionDateStruct?.date,
        hasResults: true,
      }));
  
      return {
        content: [
          {
            type: "text",
            text: JSON.stringify(
              {
                searchCriteria: {
                  status: "COMPLETED",
                  hasResults: true,
                  condition: args?.condition,
                  intervention: args?.intervention,
                  completedAfter: args?.completedAfter,
                },
                totalCount: response.data.totalCount || 0,
                resultsShown: results.length,
                studies: results,
              },
              null,
              2
            ),
          },
        ],
      };
    } catch (error) {
      if (axios.isAxiosError(error)) {
        return {
          content: [
            {
              type: "text",
              text: `Clinical Trials API error: ${
                error.response?.data?.message || error.message
              }`,
            },
          ],
          isError: true,
        };
      }
      throw error;
    }
  }

• src/index.ts:438-467 (registration)

  Tool definition for 'get_studies_with_results' in the list of available tools.

    name: "get_studies_with_results",
    description:
      "Find completed clinical trials that have published results",
    inputSchema: {
      type: "object",
      properties: {
        condition: {
          type: "string",
          description: "Medical condition to filter by",
        },
        intervention: {
          type: "string",
          description: "Treatment or intervention to filter by",
        },
        completedAfter: {
          type: "string",
          description:
            "Find studies completed after this date (YYYY-MM-DD)",
          pattern: "^\\d{4}-\\d{2}-\\d{2}$",
        },
        pageSize: {
          type: "number",
          description:
            "Number of results to return (default 10, max 100)",
          minimum: 1,
          maximum: 100,
        },
      },
    },
  },