/**
* Enhanced Supply Chain Intelligence Prompt for FDA MCP Server
* Implements AI Assistant Prompt Enhancement PRD specifications
*/
import { EnhancedPrompt, WorkingExample } from './enhanced-base.js';
import { PromptExecutionResult } from '../types/index.js';
import { SupplyChainArgsSchema, FdaSearchType } from '../types/fda.js';
interface SupplyChainArgs {
drug_name?: string;
therapeutic_area?: string;
}
export class SupplyChainPrompt extends EnhancedPrompt<SupplyChainArgs> {
constructor() {
super(
'fda_supply_chain_risk_assessment',
'Supply Chain Risk Assessment for drug manufacturing and availability. Analyzes current shortages, therapeutic vulnerability patterns, supplier concentration risks, manufacturing resilience, and discontinuation risks.',
{
drug_name: (SupplyChainArgsSchema.innerType() as any).shape.drug_name.describe('Name of the drug to analyze for supply chain risks (provide either drug_name or therapeutic_area)'),
therapeutic_area: (SupplyChainArgsSchema.innerType() as any).shape.therapeutic_area.describe('Therapeutic area to analyze for supply chain risks (provide either drug_name or therapeutic_area)')
}
);
}
protected async execute(
params: SupplyChainArgs,
_requestId: string
): Promise<PromptExecutionResult> {
const { drug_name, therapeutic_area } = params;
// Use placeholders if not provided
const therapeuticAreaName = therapeutic_area || '[THERAPEUTIC_AREA]';
const genericName = drug_name || '[GENERIC_NAME]';
// Base prompt content with optimized 5-query framework from fda-guide.md
const basePrompt = `Analyze supply chain risks for ${drug_name || therapeutic_area} with these optimized queries:
1. Active shortages in therapeutic area:
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "therapeutic_category:${therapeuticAreaName}",
"search_type": "shortages",
"limit": 5,
"fields_for_shortages": "generic_name,company_name,status,shortage_reason"
}
2. Shortage patterns by therapeutic category:
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "status:Current",
"search_type": "shortages",
"count": "therapeutic_category",
"limit": 8
}
3. Market concentration risk for specific drugs:
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "openfda.generic_name:${genericName} AND products.marketing_status:Prescription",
"count": "sponsor_name",
"limit": 5
}
4. Manufacturing diversity for drug formulations:
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "openfda.generic_name:${genericName} AND products.marketing_status:Prescription",
"limit": 3,
"fields_for_general": "sponsor_name,products.dosage_form,products.route"
}
5. Upcoming supply exits (discontinuation risk):
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "discontinued_date:*",
"search_type": "shortages",
"limit": 3,
"fields_for_shortages": "generic_name,company_name,discontinued_date"
}
**Critical Parameter Findings:**
- **Therapeutic categories are case-sensitive**: Use "Oncology", "Pediatric", "Cardiovascular" (not "oncology" or "ONCOLOGY")
- **Shortage wildcards don't work**: Use \`status:Current\` instead of \`search_term="*"\` for general patterns
- **Quote complex status values**: Use \`status:"To Be Discontinued"\` (with quotes) for multi-word statuses
**Analysis Framework:**
- Active disruptions: Current shortages and their root causes
- Therapeutic vulnerability: Categories most prone to shortages
- Supply concentration: Single vs multi-supplier dependency
- Manufacturing resilience: Formulation and delivery redundancy
**Output Format:**
1. **Current Supply Status** (3 bullets): Active shortages, primary causes, affected categories
2. **Risk Assessment** (table): Supplier concentration and vulnerability metrics
3. **Mitigation Strategy** (1 paragraph): Supply chain diversification and contingency recommendations
Execute each query sequentially and provide comprehensive supply chain intelligence with shortage analysis, market concentration assessment, and strategic risk mitigation recommendations.`;
// Create simplified prompt with schema reference
const simplifiedPrompt = `šØ EXECUTE EXACTLY: Use the fda_info tool with the provided JSON parameters below.
š SCHEMA REFERENCE:
- Use the fda_info tool schema parameters: method, search_term, search_type, count, limit
- For field validation, check the tool's built-in schema validation
- Available search_type options: "general", "label", "adverse_events", "recalls", "shortages"
- count parameter accepts field names from the FDA database
- fields_for_shortages accepts comma-separated field names for targeted shortage searches
- fields_for_general accepts comma-separated field names for targeted general searches
${basePrompt}`;
return this.createPromptResult(
`Supply Chain Risk Assessment for ${drug_name || therapeutic_area}`,
simplifiedPrompt
);
}
/**
* Get prompt-specific working examples for supply chain analysis
*/
protected getPromptSpecificExamples(): WorkingExample[] {
return [
{
name: "Active Shortages in Therapeutic Area",
description: "Find current shortages with comprehensive details",
query: {
method: "lookup_drug",
search_term: "therapeutic_category:Oncology",
search_type: "shortages",
limit: 5,
fields_for_shortages: "generic_name,company_name,status,shortage_reason"
},
expectedFields: ["generic_name", "company_name", "status", "shortage_reason"],
notes: "Therapeutic categories are case-sensitive: use proper case"
},
{
name: "Shortage Patterns by Category",
description: "Count which therapeutic areas have most shortages",
query: {
method: "lookup_drug",
search_term: "status:Current",
search_type: "shortages",
count: "therapeutic_category",
limit: 8
},
expectedFields: ["therapeutic_category"],
notes: "Use status:Current to filter for active shortages only"
},
{
name: "Market Concentration Risk",
description: "Count manufacturers supplying a specific drug",
query: {
method: "lookup_drug",
search_term: "openfda.generic_name:adalimumab AND products.marketing_status:Prescription",
search_type: "general",
count: "sponsor_name",
limit: 5
},
expectedFields: ["sponsor_name"],
notes: "Fewer sponsors = higher concentration risk and shortage vulnerability"
},
{
name: "Upcoming Supply Exits",
description: "Find drugs with discontinuation dates",
query: {
method: "lookup_drug",
search_term: "discontinued_date:*",
search_type: "shortages",
limit: 3,
fields_for_shortages: "generic_name,company_name,discontinued_date"
},
expectedFields: ["generic_name", "company_name", "discontinued_date"],
notes: "Provides actual discontinuation timeline with dates and companies"
}
];
}
/**
* Get the primary search type for this prompt
*/
protected getPrimarySearchType(): FdaSearchType {
return 'shortages';
}
}
