/**
* Enhanced Generic Competition Assessment Prompt
* Implements AI Assistant Prompt Enhancement PRD specifications
* Comprehensive generic competition assessment for Orange Book FDA analysis
*/
import { EnhancedPrompt, WorkingExample } from './enhanced-base.js';
import { PromptExecutionResult } from '../types/index.js';
import { GenericCompetitionArgsSchema, FdaSearchType } from '../types/fda.js';
interface GenericCompetitionArgs {
brand_drug?: string;
generic_name?: string;
}
export class GenericCompetitionPrompt extends EnhancedPrompt<GenericCompetitionArgs> {
constructor() {
super(
'fda_generic_competition_landscape',
'Comprehensive generic competition assessment for Orange Book FDA analysis. Evaluates market entry patterns, competitive landscape, reference vs generic drug distinction, and market maturity indicators.',
{
brand_drug: (GenericCompetitionArgsSchema.innerType() as any).shape.brand_drug.describe('Brand name of the drug to analyze for generic competition (provide either brand_drug or generic_name)'),
generic_name: (GenericCompetitionArgsSchema.innerType() as any).shape.generic_name.describe('Generic name of the drug to analyze for generic competition (provide either brand_drug or generic_name)')
}
);
}
protected async execute(
params: GenericCompetitionArgs,
_requestId: string
): Promise<PromptExecutionResult> {
const { brand_drug, generic_name } = params;
// For the prompt, we need both brand drug and generic name placeholders
const brandDrugName = brand_drug || '[BRAND_DRUG]';
const genericDrugName = generic_name || '[GENERIC_NAME]';
// Base prompt content with optimized 5-query framework from fda-guide.md
const basePrompt = `Assess generic competition for ${brandDrugName} with these optimized queries:
1. Brand drug details and originator sponsor:
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "products.brand_name:${brandDrugName} OR openfda.generic_name:${genericDrugName}",
"limit": 1,
"fields_for_general": "openfda.brand_name"
}
2. Total competitive landscape:
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "openfda.generic_name:${genericDrugName} AND products.marketing_status:Prescription",
"count": "sponsor_name",
"limit": 15
}
3. Reference vs generic distinction:
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "openfda.generic_name:${genericDrugName} AND products.marketing_status:Prescription",
"count": "products.reference_drug",
"limit": 15
}
4. Latest generic entries:
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "openfda.generic_name:${genericDrugName} AND products.reference_drug:No",
"count": "sponsor_name",
"limit": 15
}
5. Market timeline efficiency:
- Tool: fda_info
- EXECUTE EXACTLY:
{
"method": "lookup_drug",
"search_term": "openfda.generic_name:${genericDrugName} AND products.marketing_status:Prescription",
"count": "submissions.submission_status_date",
"limit": 15
}
notes:
- Focus on statistical patterns for competitive positioning analysis
**Output Format:**
1. **Competition Status** (1 short paragraph): Total manufacturers, originator vs generics, market maturity + Full list of manufacturers (table): just the name of each manufacturer indicating the originator
2. **Competitive Timeline** (table): Shows Market entry progression over time
3. **Market Assessment** (2 paragraphs): Competition intensity, recent entries, strategic implications
Execute each query sequentially and provide comprehensive Orange Book FDA analysis covering market entry patterns, competitive landscape, and market maturity indicators.`;
// Create simplified prompt with schema reference
const simplifiedPrompt = `EXECUTE EXACTLY: Use the fda_info tool with the provided JSON parameters below.
SCHEMA REFERENCE:
- Use the fda_info tool schema parameters: method, search_term, search_type, count, limit
- For field validation, check the tool's built-in schema validation
- Available search_type options: "general", "label", "adverse_events", "recalls", "shortages"
- count parameter accepts field names from the FDA database
- fields_for_general accepts single field names for targeted searches
${basePrompt}`;
return this.createPromptResult(
`Orange Book FDA Generic Competition Assessment for ${brandDrugName}`,
simplifiedPrompt
);
}
/**
* Get prompt-specific working examples for generic competition analysis
*/
protected getPromptSpecificExamples(): WorkingExample[] {
return [
{
name: "Brand Drug Details",
description: "Get brand drug details and originator information",
query: {
method: "lookup_drug",
search_term: "products.brand_name:HUMIRA OR openfda.generic_name:adalimumab",
search_type: "general",
limit: 1,
fields_for_general: "openfda.brand_name"
},
expectedFields: ["openfda.brand_name"],
notes: "Identifies brand drug and originator information"
},
{
name: "Total Competitive Landscape",
description: "Count all sponsors manufacturing the generic drug",
query: {
method: "lookup_drug",
search_term: "openfda.generic_name:adalimumab AND products.marketing_status:Prescription",
search_type: "general",
count: "sponsor_name",
limit: 8
},
expectedFields: ["sponsor_name"],
notes: "Shows competitive intensity: more sponsors = higher competition"
},
{
name: "Reference vs Generic Distinction",
description: "Count reference vs generic drug classification",
query: {
method: "lookup_drug",
search_term: "openfda.generic_name:adalimumab AND products.marketing_status:Prescription",
search_type: "general",
count: "products.reference_drug",
limit: 3
},
expectedFields: ["products.reference_drug"],
notes: "Count query provides instant market maturity assessment"
},
{
name: "Market Timeline Efficiency",
description: "Get application numbers for timeline analysis",
query: {
method: "lookup_drug",
search_term: "openfda.generic_name:adalimumab AND products.marketing_status:Prescription",
search_type: "general",
count: "application_number",
limit: 3
},
expectedFields: ["application_number"],
notes: "Efficient timeline data using application number counts for market entry patterns"
}
];
}
/**
* Get the primary search type for this prompt
*/
protected getPrimarySearchType(): FdaSearchType {
return 'general';
}
}
