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  • hgnc-link

    berntpopp
    A
    license
    A
    quality
    A
    maintenance
    Grounds gene-nomenclature work in the HUGO Gene Nomenclature Committee (HGNC) dataset, enabling resolution of gene symbols and IDs to canonical HGNC identifiers, plus cross-references and batch operations.
    Last updated
    9
    MIT

  • metadome-link

    berntpopp
    A
    license
    A
    quality
    A
    maintenance
    Enables querying of per-residue missense tolerance, Pfam domain annotations, and variant counts for human transcripts by wrapping the MetaDome web service. Provides MCP tools for resolving transcripts, requesting tolerance landscapes, and identifying constrained regions.
    Last updated
    11
    MIT

  • rnaseq-mcp

    sbarbi-gh
    F
    license
    A
    quality
    C
    maintenance
    Enables analysis of bulk RNA-seq data using natural language queries, executing R and Python in a Docker container with automatic sample anonymization and privacy controls.
    Last updated
    7

  • uniprot-mcp

    fzlzjerry
    A
    license
    A
    quality
    B
    maintenance
    MCP server that exposes the UniProt REST API to LLM clients, enabling search and retrieval of protein data via tools like search_uniprotkb, get_entry, and map_ids.
    Last updated
    7
    MIT
  • Noctua MCP Server by geneontology

    Noctua MCP Serverofficial

    geneontology
    A
    license
    A
    quality
    C
    maintenance
    Enables editing and querying of Gene Ontology Causal Activity Models (GO-CAMs) through the Barista API. Supports model creation, individual and fact management, evidence addition, and causal pathway construction for biological knowledge representation.
    Last updated
    18
    BSD 3-Clause

  • Enrichr MCP Server

    tianqitang1
    A
    license
    A
    quality
    B
    maintenance
    Enables gene set enrichment analysis using the Enrichr API across hundreds of gene set libraries including Gene Ontology, pathways, diseases, tissues, drugs, and transcription factors. Returns only statistically significant results for interpretation.
    Last updated
    2
    357
    15
    MIT

  • MCP Sequence Simulation Server

    coreymhudson
    A
    license
    A
    quality
    D
    maintenance
    Enables the generation, mutation, and evolution of DNA and protein sequences using various evolutionary models and phylogenetic algorithms. It supports realistic next-generation sequencing read simulation and population-level evolutionary tracking for bioinformatics research and testing.
    Last updated
    6
    BSD 2-Clause "Simplified"

  • Rowan MCP Server

    k-yenko
    A
    license
    B
    quality
    F
    maintenance
    Enables molecular design and simulation through 45 chemistry tools including pKa calculations, geometry optimization, conformer searches, docking, protein cofolding, and ADMET predictions powered by Rowan's computational chemistry platform.
    Last updated
    41
    23
    MIT

  • AGR MCP Server

    nuin
    A
    license
    B
    quality
    C
    maintenance
    Enables querying genomics data from the Alliance of Genome Resources across model organisms including human, mouse, rat, zebrafish, fly, worm, yeast, and xenopus. Supports gene searches, disease associations, expression data, orthologs, phenotypes, and molecular interactions through natural language.
    Last updated
    22
    22
    MIT

  • miEAA3 MCP Server

    kkShrihari
    F
    license
    B
    quality
    D
    maintenance
    Integrates the miEAA 3.x bioinformatics platform with Claude Desktop, enabling microRNA enrichment analysis, identifier conversion between miRBase versions, and miRNA-precursor transformations through natural language.
    Last updated
    4

  • AlphaGenome MCP Server

    taehojo
    A
    license
    B
    quality
    D
    maintenance
    Enables AI-powered genomic variant analysis including variant impact prediction, regulatory element discovery, and batch variant scoring. Currently operates in mock mode as a proof-of-concept awaiting the public release of Google DeepMind's AlphaGenome API.
    Last updated
    20
    14
    2
    MIT
  • NGS360 MCP Server by NGS360

    NGS360 MCP Serverofficial

    NGS360
    F
    license
    C
    quality
    B
    maintenance
    Exposes the NGS360 bioinformatics platform REST API as MCP tools, enabling AI assistants to manage sequencing runs, projects, workflows, and more through natural language.
    Last updated
    82

  • Bio-OS MCP Server

    GBA-BI
    A
    license
    C
    quality
    B
    maintenance
    Enables workflow management and Docker image building for Bio-OS platform. Supports WDL workflow submission, validation, and monitoring, along with Docker image building and status tracking for bioinformatics workflows.
    Last updated
    22
    5
    MIT