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  • A
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    Enables AI agents to search EBI BioSamples metadata for biological samples such as cell lines, tissues, and organisms by free-text keyword, and to fetch individual records by accession to retrieve taxId, organism, and characteristics like tissue, sex, and cell type. It can run as a hosted gateway endpoint or locally over stdio via npx.
    412 npm
    MIT
  • A
    license
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    quality
    B
    maintenance
    Enables users to search and retrieve 3D cryo-EM and electron-tomography density maps by keyword or entry ID, returning details such as resolution, structure-determination method, sample, and release date.
    449 npm
    1
    MIT
  • A
    license
    Not graded
    quality
    C
    maintenance
    Enables searching EBI BioStudies, a keyless database of biological study descriptions, by keyword and retrieving full metadata for a single study by accession, including title, abstract, release date, and link counts. Results tie studies across EBI archives such as ArrayExpress and PRIDE, so agents can locate and inspect study records without authentication.
    394 npm
    MIT
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    A
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    Enables AI assistants to rapidly gather and synthesize structural, chemical, conservation, and literature data about protein binding pockets for drug-target triage. Useful as a reconnaissance step before computational binder design.
    8
    1
    MIT
  • A
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    A
    quality
    B
    maintenance
    MCP server for the STRING protein–protein interaction database, hosted by STRING at mcp.string-db.org. Adapted for LLM grounding: responses are size-limited and include metadata and notes on interpretation and next steps. Tools cover identifier resolution, interaction networks and evidence, functional and PPI enrichment, and sequence similarity search.
    17
    8
    MIT
  • A
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    A
    quality
    B
    maintenance
    MCP server offering verified bioinformatics tools for sequence utilities and statistics, backed by BioPython/scipy. Enables AI agents to perform accurate GC content, translation, ORF finding, motif scanning, and statistical tests through natural language.
    11
    MIT
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    A
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    Enables LLM agents to search EMDB cryo-EM maps, look up UniProt proteins, compute ESM-2 sequence embeddings, retrieve cryo-EM maps from a protein sequence via a two-tower model, and search GEO DNA-methylation arrays, all through typed tools with structured output. Ships with a 40-question evaluation harness that runs Claude as the MCP client.
    3
    MIT
  • A
    license
    A
    quality
    A
    maintenance
    An MCP server that gives AI assistants access to biological and biomedical RDF databases via SPARQL at the RDF Portal, as well as selected REST APIs (NCBI E-utilities, UniProt, ChEMBL, PDB, Reactome, Rhea, MeSH, and more).
    2
    29
    21
    MIT
  • A
    license
    A
    quality
    A
    maintenance
    Enables AI agents to resolve and cross-reference biological entities such as genes, proteins, and aliases across authoritative databases like HGNC, NCBI Entrez, and UniProt, with confidence scores and source citations.
    16
    2
    Apache 2.0
  • A
    license
    A
    quality
    B
    maintenance
    Enables citation-grounded biomedical literature review by searching PubMed, retrieving abstracts from Europe PMC, and looking up gene and protein records from NCBI Gene and UniProt, with every cited PMID verified to exist and support its claim. All tools are read-only, so Claude can only cite papers actually retrieved and read during the session.
    4
    MIT
  • A
    license
    A
    quality
    C
    maintenance
    Enables AI assistants to query the eggNOG 7 database in natural language for protein lookups, orthologous groups, pairwise orthologs, protein families, taxonomy, and database statistics. Also delivers structured functional annotations such as KEGG KO and GO terms with confidence scores, plus an index of bulk-downloadable data files.
    10
    1
    MIT
  • A
    license
    A
    quality
    B
    maintenance
    This server provides agents with access to key data across UniProt, RCSB PDB, and ChEMBL archives. It enables the completion of complex biochemical and drug discovery tasks by offering structured tool endpoints.
    6
    MIT
  • A
    license
    A
    quality
    B
    maintenance
    Enables MCP clients to discover and call typed tools for protein backbone design, sequence design, complex folding, and binder design via BioNeMo NIMs, with a deterministic simulator by default and optional live routing.
    5
    Apache 2.0
  • A
    license
    A
    quality
    C
    maintenance
    Enables users to search rRNA sequences by organism, accession, or taxonomy, retrieve detailed sequence metadata, evaluate probes and primer pairs, and list available databases and taxonomies through MCP tools.
    6
    1
    MIT
  • A
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    Enables AI-driven pharmacogenomic analysis by querying structured genetic variant, drug response, and disease risk data. Supports natural language questions about medications, traits, and health risks based on user genome data, with privacy-first local execution.
    16
    16 npm
    12
    MIT
  • A
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    A
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    B
    maintenance
    Reads raw lab-instrument files (microscopy, mass spectrometry, chromatography, flow cytometry, NMR, electrophysiology, spectroscopy, plate readers, qPCR) without vendor software, returning metadata, images, spectra and traces as JSON. It also checks files for damage, runs common analyses, and exports to open formats such as OME-TIFF, OME-Zarr, mzML, Parquet and NWB.
    28
    284 PyPI
    12
    Apache 2.0
  • A
    license
    A
    quality
    A
    maintenance
    Enables AI-powered genomic variant analysis including variant impact prediction, regulatory element discovery, and batch variant scoring. Currently operates in mock mode as a proof-of-concept awaiting the public release of Google DeepMind's AlphaGenome API.
    24
    27 npm
    2
    MIT
  • A
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    Enables molecular design and simulation through 45 chemistry tools including pKa calculations, geometry optimization, conformer searches, docking, protein cofolding, and ADMET predictions powered by Rowan's computational chemistry platform.
    41
    24
    MIT
  • A
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    Enables AI assistants to query antimicrobial resistance data from the NCBI Reference Gene Catalog, NCBI E-utilities and UniProtKB, and optionally screen genomes with a local AMRFinderPlus install. Supports searching genes by drug class or organism, retrieving allele records, fetching sequences and PubMed references, and looking up protein annotations.
    10
    MIT
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    Exposes phylogenetic tree validation, analysis, styling, export, and Java-based rendering as 21 MCP tools, 3 resources, and 2 prompts for AI assistants. Delegates parsing and rendering to the FigTreeKit kernel, returning reproducible CLI commands and structured artifacts.
    21
    1
    GPL 2.0
  • F
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    Enables users to generate volcano plots by submitting jobs with input files and parameters, supporting local or Docker execution.
    8
    1
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  • A
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    Enables reproducible target-disease evidence dossier assembly and validation by replaying frozen Open Targets GraphQL responses and checking citations and structured assertions against deterministic scientific contracts.
    2
    Apache 2.0
  • A
    license
    B
    quality
    B
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    Predicts CRISPR gene dependencies and drug targets by integrating literature, regulatory/PPI networks, and genome-scale metabolic models.
    18
    Apache 2.0
  • A
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    B
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    Enables proposing OBO-grounded AVUs for datasets by ranking candidate ontology terms plus a fixed none-of-these anchor with Contrastive LM and deterministic OBO/OLS tools. Records every annotation decision in provenance next to AVU history.
    50
    MIT
  • F
    license
    C
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    Exposes the NGS360 bioinformatics platform REST API as MCP tools, enabling AI assistants to manage sequencing runs, projects, workflows, and more through natural language.
    82
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