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  • A
    license
    Not graded
    quality
    B
    maintenance
    An embedded MCP server for Cytoscape Desktop that lets AI agents load networks, set active views, and control the desktop application over HTTP.
    8
    BSD 3-Clause
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI agents to search and retrieve compounds, drugs, diseases, pathways, genes, enzymes, glycans, modules, and KO entries; fetch full parsed flat-file entries by ID; and list database contents through keyless REST tools.
    373 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables keyless lookup of marine species and genus names, retrieval of full taxonomic lineages by AphiaID, and common vernacular names across languages via MCP tools.
    187 npm
    MIT
  • A
    license
    Not graded
    quality
    C
    maintenance
    Enables AI assistants to query VCF files through MCP tools that summarize variants, identify pathogenic and carrier variants, interpret pharmacogenomic results, and determine APOE status, with web app and Claude Desktop support.
    MIT
  • A
    license
    A
    quality
    D
    maintenance
    Provides direct SQL access to a locally hosted Reactome database, enabling schema discovery, guarded read-only queries, and ergonomic helpers over the full relational schema.
    9
    MIT
  • A
    license
    A
    quality
    C
    maintenance
    Enables LLM agents to search biomedical literature, retrieve article details, find related papers, manage caching, and download open-access full texts through MCP with structured, agent-friendly responses.
    5
    Apache 2.0
  • A
    license
    A
    quality
    A
    maintenance
    A bridge connecting AI agents to NCBI's PubMed database through the Model Context Protocol, enabling seamless searching, retrieval, and analysis of biomedical literature and data.
    12
    5,889 npm
    163
    Apache 2.0
  • A
    license
    A
    quality
    C
    maintenance
    Enables LLM-powered applications to look up bacterial and archaeal taxonomy, search genomes, browse and navigate the taxonomic tree, and compare genomes or find phylogenetic paths between taxa. It works out of the box with a built-in reference dataset covering major phyla and can be pointed at full Genome Taxonomy Database TSV files for comprehensive queries.
    12
    1
    MIT
  • A
    license
    A
    quality
    C
    maintenance
    Enables AI assistants to search and retrieve prokaryotic names, taxon details, full classifications, and rank-based browsing from the List of Prokaryotic names with Standing in Nomenclature in real time, plus read related information pages.
    7
    1
    MIT
  • A
    license
    B
    quality
    C
    maintenance
    Enables AI assistants to query and retrieve microbial nomenclature data from the SeqCode Registry through its public REST API. Provides 18 tools for names, genomes, type genomes, register lists, publications, authors, journals, subjects, strains, and full-text search, with pagination and status filtering.
    18
    1
    MIT
  • A
    license
    B
    quality
    D
    maintenance
    Provides seamless access to UniProtKB protein database, enabling queries for protein entries, sequences, Gene Ontology annotations, full-text search, and ID mapping across 200+ database types.
    5
    2
    MIT
  • A
    license
    B
    quality
    B
    maintenance
    Enables LLM agents to query the CZ CELLxGENE Census single-cell atlas with ontology-aware filters, cost caps, and full provenance, allowing natural language questions about cell types, tissues, and gene expression.
    13
    22 PyPI
    MIT
  • A
    license
    B
    quality
    A
    maintenance
    Parses MS-DIAL binary lipidomics outputs and runs standard analyses server-side, returning compact summaries so an LLM can drive full lipidomics analysis without exposing raw matrices.
    77
    MIT
  • A
    license
    B
    quality
    C
    maintenance
    Enables MCP-capable AI clients to characterize proteins end to end: PDB/mmCIF validation, sequence extraction and typing, pLDDT confidence summaries, metal-site geometry with bidentate chelate detection, GROMACS trajectory metrics and plots, and live UniProt, AlphaFold DB, and RCSB lookups. Also ships a point-and-click Protein Lab web UI (and a persistent run registry) so students and wet-lab biologists can get the same results without any client setup.
    31
    MIT
  • A
    license
    C
    quality
    A
    maintenance
    Enables querying of per-residue missense tolerance, Pfam domain annotations, and variant counts for human transcripts by wrapping the MetaDome web service. Provides MCP tools for resolving transcripts, requesting tolerance landscapes, and identifying constrained regions.
    11
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI agents to search public cancer genomics studies (TCGA, CPTAC, MSK, and more), fetch full details for individual studies, resolve gene symbols to Entrez ids, and list cancer types. Works keylessly against open cBioPortal data over a hosted MCP endpoint, a local stdio server, or plain HTTP.
    414 npm
    MIT
  • A
    license
    Not graded
    quality
    C
    maintenance
    Enables AI agents to resolve genes, diseases, chemicals, variants and species to normalized ids, search ~36M PubMed abstracts and PMC full texts by free text or entity, and retrieve the machine-extracted relations between them with the supporting sentences and PMIDs. Supports auditing individual relations with full evidence passages and pulling per-article entity annotations with character offsets.
    9 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    MCP server for querying gene annotations, full-text gene search, and species taxonomy via MyGene.info. Enables AI agents to access gene data through natural language questions.
    9 npm
    MIT
  • A
    license
    Not graded
    quality
    C
    maintenance
    An MCP server providing public plant bioinformatics APIs including UniProt, NCBI, InterProScan, PDB, AlphaFold, Ensembl Plants, and web-based resources like Sol Genomics and BAR, without local data. It supports gene lookups, protein summaries, structure retrieval, and functional annotations through natural language.
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI agents to look up approved human genes by official symbol, fuzzy-search symbols, names and aliases, and reverse-map external database identifiers (Entrez, Ensembl, UniProt, OMIM, RefSeq, UCSC) back to canonical gene records with full annotations and cross-references.
    407 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI agents to resolve scientific (Latin binomial) names to Open Tree of Life taxon IDs, retrieve full taxonomic details, synonyms, and ancestor lineages, and find the most recent common ancestor of up to 10 taxa within the synthetic tree of life. Runs keylessly over a hosted gateway endpoint or locally via npx.
    344 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI agents to search roughly 150 million digitized natural-history museum specimen records (plants, animals, fossils) from US collections, filtered by taxonomy and locality, and to retrieve the full normalized record for any single specimen by its uuid. It also returns taxonomic or geographic specimen counts grouped by a chosen field, optionally narrowed by the same filters, with no API key required.
    407 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables searching EBI BioStudies, a keyless database of biological study descriptions, by keyword and retrieving full metadata for a single study by accession, including title, abstract, release date, and link counts. Results tie studies across EBI archives such as ArrayExpress and PRIDE, so agents can locate and inspect study records without authentication.
    394 npm
    MIT