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  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI agents to query Human Phenotype Ontology clinical phenotype terms, navigate term hierarchies, and retrieve gene-disease and disease-phenotype annotations through keyless MCP tools.
    383 npm
    MIT
  • A
    license
    A
    quality
    B
    maintenance
    Enables MCP clients to annotate and classify single human genetic variants in any notation, returning an auditable points-based ACMG verdict with its criteria, gnomAD frequencies, in-silico predictors, ClinVar data, and per-transcript consequences. It is read-only, requires no account or API key, and keeps answers compact while linking back to the source.
    6
    MIT
  • A
    license
    B
    quality
    D
    maintenance
    Server to search PubMed (PubMed is a free, online database that allows users to search for biomedical and life sciences literature). I have created on a day MCP came out but was on vacation, I saw someone post similar server in your DB, but figured to post mine.
    1
    46
    MIT
  • F
    license
    C
    quality
    B
    maintenance
    Exposes the NGS360 bioinformatics platform REST API as MCP tools, enabling AI assistants to manage sequencing runs, projects, workflows, and more through natural language.
    82
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  • A
    license
    Not graded
    quality
    C
    maintenance
    Enables querying NCBI genome assemblies, gene details with cross-references, and taxonomy trees with per-node assembly and gene counts, providing structured answers about genomes, genes, and taxonomy.
    381 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Federates 13 gene-related MCP backends (gnomAD, GTEx, etc.) behind a single Streamable HTTP endpoint with collision-free namespacing and search-based tool discovery.
    6
    MIT
  • A
    license
    Not graded
    quality
    D
    maintenance
    πŸ” A biomedical literature annotation and relationship mining server based on PubTator3, providing convenient access through the MCP interface.
    10
    MIT
  • A
    license
    Not graded
    quality
    A
    maintenance
    Enables Claude and other MCP clients to run fast, exactly scored similarity and substructure searches over a local PubChem fingerprint index, pull live PubChem records (identifiers, synonyms, GHS, bioassays) with cited sources, and compute offline RDKit descriptors, med-chem alerts and highlighted structure drawings β€” all without API rate limits.
    292 PyPI
    9
    MIT
  • F
    license
    Not graded
    quality
    D
    maintenance
    A terminal-based bioinformatics CLI chat tool that integrates Ensembl VEP, NCBI ClinVar, an MCP server layer, and OpenRouter's NVIDIA Nemotron 3 Ultra model to provide variant consequence and clinical significance lookups with clear summaries in a Rich-powered CLI.
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  • A
    license
    A
    quality
    A
    maintenance
    Enables language models to search biomedical literature, fetch sequences, and follow links across Entrez databases through eleven read-only tools wrapping the nine NCBI Entrez E-utilities. It handles URL building, pacing, redirects, response caps, and API-key redaction so queries can be answered without a browser or scraping.
    11
    MIT
  • A
    license
    A
    quality
    A
    maintenance
    Grounds gene-nomenclature work in the HUGO Gene Nomenclature Committee (HGNC) dataset, enabling resolution of gene symbols and IDs to canonical HGNC identifiers, plus cross-references and batch operations.
    9
    MIT
  • A
    license
    A
    quality
    B
    maintenance
    Enables AI agents to retrieve cited pharmacogenomic and gene-variant information, including drug–gene guidance from CPIC/DPWG and rsID lookups, so responses can quote curated sources instead of relying on memory. A local package also lets users read raw DNA files on their own computer without sending the file data to the remote service.
    2
    43 PyPI
    MIT
  • A
    license
    A
    quality
    D
    maintenance
    Enables coding agents to interact with the Reactome pathway database, including search, lookup, hierarchy traversal, SBML/SBGN export, and gene-set enrichment analysis.
    17
    MIT
  • A
    license
    A
    quality
    D
    maintenance
    Provides direct SQL access to a locally hosted Reactome database, enabling schema discovery, guarded read-only queries, and ergonomic helpers over the full relational schema.
    9
    MIT