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clinicaltrialsgov-mcp-server

by cyanheads

Version License Docker MCP SDK npm TypeScript Bun

Install in Claude Desktop Install in Cursor Install in VS Code

Framework

Public Hosted Server: https://clinicaltrials.caseyjhand.com/mcp


Overview

Clinical trial data from the ClinicalTrials.gov REST API v2 — the US National Library of Medicine's registry of ~577K clinical trial studies. Search trials, fetch full study records and posted results, discover field names and valid values, and match patient demographics to eligible recruiting trials. Public, read-only, no authentication required. Runs as a stdio process, a local Streamable HTTP server, or the public hosted endpoint above.

Tools

Tool

Description

clinicaltrials_search_studies

Search studies with full-text and field-specific queries, status/phase/geographic filters, pagination, sorting, and field selection

clinicaltrials_get_study_record

Fetch a single study by NCT ID — full protocol record with optional location/outcome/reference caps

clinicaltrials_get_study_count

Fast total study count for a query, without fetching data

clinicaltrials_get_field_values

Discover valid values for API fields, with per-value study counts

clinicaltrials_get_field_definitions

Resolve valid field names — keyword search, path drill-down, or top-level overview

clinicaltrials_get_study_results

Fetch posted results — outcomes, adverse events, participant flow, baseline — for completed studies

clinicaltrials_find_eligible

Match patient demographics and conditions to eligible recruiting trials

Resources

Resource

Description

clinicaltrials://{nctId}

Fetch a single clinical study by NCT ID as JSON, with capped lists and results replaced by counts

Prompts

Prompt

Description

analyze_trial_landscape

Guides a data-driven clinical trial landscape analysis using the count and search tools

Related MCP server: ClinicalTrials.gov MCP Server

Capability reference

clinicaltrials_search_studies tool

  • Free-text query plus field-specific conditionQuery / interventionQuery / locationQuery / sponsorQuery / titleQuery / outcomeQuery; statusFilter / phaseFilter enums, advancedFilter (AREA[FieldName]value / RANGE[min, max] syntax), and geoFilter (distance(lat,lon,radius) with a mi/km suffix) for proximity search with nearest-site re-ranking

  • Returns a compact per-study index by default (nctId, briefTitle, overallStatus, phases, enrollmentCount, leadSponsor, conditions, a bounded locations summary); pass fields (PascalCase leaves) for a full-fidelity projection — full records run ~70KB

  • pageSize 1–CT_MAX_PAGE_SIZE (default 200), cursor pagination via pageToken, sort on up to 2 fields

  • Excludes the upstream "unknown" enrollment sentinel (99999999) by default — includeUnknownEnrollment to include it, or automatically lifted when nctIds is supplied

  • Typed errors: blank_value, ids_not_found, field_invalid, enum_invalid, query_parse_error, geo_invalid, sort_invalid, rate_limited


clinicaltrials_get_study_record tool

  • Full protocol record by NCT ID — identification, status, sponsor, conditions, design, arms/interventions, outcomes, eligibility, contacts/locations

  • Optional locationLimit (≤500), outcomeLimit / referenceLimit (≤100), and nearLocation (lat, lon, radiusMi default 50) to bound and sort locations; upstream totals reported in filtersApplied only when a cap actually trims the list

  • resultsSection is replaced by compact resultsSummary counts — fetch full results via clinicaltrials_get_study_results

  • Typed errors: study_not_found, rate_limited


clinicaltrials_get_study_count tool

  • Same query/filter surface as clinicaltrials_search_studies (free-text and field-specific queries, status/phase filters, advancedFilter) but returns only totalCount — no study data fetched

  • Excludes the unknown-enrollment sentinel by default (includeUnknownEnrollment to include it)

  • Typed errors: blank_value, field_invalid, enum_invalid, query_parse_error, rate_limited


clinicaltrials_get_field_values tool

  • One or more PascalCase field names (e.g. OverallStatus, Phase, LeadSponsorClass) — returns each field's type, unique-value count, and top values with study counts (capped at 250 by the API)

  • Numeric/date fields report min / max / avg / formats instead of top values; boolean fields report trueCount / falseCount

  • multiValued flags fields where a study can carry several values, so per-value study counts can sum above the study total

  • Typed errors: blank_value, field_invalid, rate_limited


clinicaltrials_get_field_definitions tool

  • Three modes: search (keyword, ranked matches, limit up to 100, default 20), drill (dot-notation path into a section), overview (top-level sections, no other args)

  • Resolves the canonical PascalCase field names accepted by fields, advancedFilter, sort, and clinicaltrials_get_field_values

  • Typed errors: blank_value, mode_mismatch, mode_requires, path_not_found, rate_limited


clinicaltrials_get_study_results tool

  • Up to 20 NCT IDs per call; only returns data for studies where hasResults is true — outcome measures, adverse events, participant flow, baseline characteristics, and results metadata

  • summary (default false) condenses a full result set — which can exceed 500KB per study — to a few KB; full mode supports outcomeLimit (≤100) and adverseEventLimit (≤500), resumable via outcomeOffset / seriousEventOffset / otherEventOffset

  • sections filters to outcomes, adverseEvents, participantFlow, baseline, moreInfo

  • A previous (alias) NCT ID resolves to its canonical study, named in canonicalNctId

  • Typed errors: blank_value, offset_not_applicable, rate_limited


clinicaltrials_find_eligible tool

  • Takes age, sex (FEMALE / MALE / ALL), conditions[], location (country required, state / city optional), healthyVolunteer, recruitingOnly (default true), maxResults (≤50)

  • Re-ranks results so studies whose own condition list names a requested condition surface above tangential MeSH-umbrella matches from the upstream fuzzy search

  • Bounds each candidate's locations to the sites matching the requested location (capped by locationLimit, ≤500) instead of every registered site, adding the nearest recruiting site when none of the matched ones is open

  • funnel reports match counts at each filter stage (condition → +location → +demographics) to show where the query narrowed to zero

  • Typed errors: blank_value, rate_limited


clinicaltrials://{nctId} resource

  • Full protocol record as application/json, with locations, secondary/other outcomes, and references each capped at 50 — fixed server-side, no arguments

  • Results data is replaced by resultsSummary counts; truncated and filtersApplied disclose what was capped, with retrieval naming the tools that fetch the full data

  • Typed errors: study_not_found, rate_limited


analyze_trial_landscape prompt

  • Arguments: topic required; focusAreas (comma-separated) optional

  • Returns one user message pointing the agent at the count, search, field-discovery, and results tools for a data-driven landscape analysis

Features

Built on @cyanheads/mcp-ts-core: stdio and Streamable HTTP transports, pluggable auth (none / jwt / oauth), swappable storage (in-memory, filesystem, Supabase, Cloudflare KV/R2/D1), structured logging with optional OpenTelemetry tracing.

ClinicalTrials.gov-specific:

  • Type-safe client for the ClinicalTrials.gov REST API v2 — public, no authentication or API keys required

  • Serialized request queue enforcing ClinicalTrials.gov's ~1 req/sec rate limit, with retry and exponential backoff on 429/5xx responses

  • Auto-corrects field names passed to fields/sort — case/whitespace fixes and known legacy aliases (e.g. RecruitmentStatusOverallStatus) — before validating, logging every correction

  • Detects upstream HTML error pages returned with a JSON content-type and retries rather than parsing them as data

  • Geographic proximity search and nearest-site re-ranking, with no geocoding dependency

Agent-friendly output:

  • Provenance — clinicaltrials_search_studies / clinicaltrials_get_study_count / clinicaltrials_find_eligible echo searchCriteria on every call, including sentinelFilterActive when the default unknown-enrollment exclusion applies, and clinicaltrials_get_study_results names canonicalNctId when a previous (alias) ID resolves to a different study

  • Graceful partial failure — clinicaltrials_get_study_results returns per-study fetchErrors / studiesWithoutResults rows instead of failing the whole batch when one ID is malformed or lacks results

  • Discriminated output — typed error reason codes per tool (study_not_found, blank_value, offset_not_applicable, …), and bounded lists (filtersApplied, locationSummary) carry a next*Offset only when more remains, so callers branch on presence instead of parsing text

  • Response shaping — clinicaltrials_search_studies and clinicaltrials_find_eligible return a compact per-study index or location-bounded set by default instead of the ~70KB full record, escalating to full fidelity only via fields or clinicaltrials_get_study_record

Getting started

Public Hosted Instance

A public instance is available at https://clinicaltrials.caseyjhand.com/mcp — no installation required. Point any MCP client at it via Streamable HTTP:

{
  "mcpServers": {
    "clinicaltrialsgov-mcp-server": {
      "type": "streamable-http",
      "url": "https://clinicaltrials.caseyjhand.com/mcp"
    }
  }
}

Self-Hosted / Local

Add the following to your MCP client configuration file.

{
  "mcpServers": {
    "clinicaltrialsgov-mcp-server": {
      "type": "stdio",
      "command": "bunx",
      "args": ["clinicaltrialsgov-mcp-server@latest"],
      "env": {
        "MCP_TRANSPORT_TYPE": "stdio",
        "MCP_LOG_LEVEL": "info"
      }
    }
  }
}

Or with npx (no Bun required):

{
  "mcpServers": {
    "clinicaltrialsgov-mcp-server": {
      "type": "stdio",
      "command": "npx",
      "args": ["-y", "clinicaltrialsgov-mcp-server@latest"],
      "env": {
        "MCP_TRANSPORT_TYPE": "stdio",
        "MCP_LOG_LEVEL": "info"
      }
    }
  }
}

Or with Docker:

{
  "mcpServers": {
    "clinicaltrialsgov-mcp-server": {
      "type": "stdio",
      "command": "docker",
      "args": ["run", "-i", "--rm", "-e", "MCP_TRANSPORT_TYPE=stdio", "ghcr.io/cyanheads/clinicaltrialsgov-mcp-server:latest"]
    }
  }
}

For Streamable HTTP, set the transport and start the server:

MCP_TRANSPORT_TYPE=http MCP_HTTP_PORT=3010 bun run start:http
# Server listens at http://localhost:3010/mcp

Prerequisites

Installation

  1. Clone the repository:

git clone https://github.com/cyanheads/clinicaltrialsgov-mcp-server.git
  1. Navigate into the directory:

cd clinicaltrialsgov-mcp-server
  1. Install dependencies:

bun install

Configuration

All configuration is optional — the server works with defaults and no API keys.

Variable

Description

Default

CT_API_BASE_URL

ClinicalTrials.gov API base URL.

https://clinicaltrials.gov/api/v2

CT_REQUEST_TIMEOUT_MS

Per-request timeout in milliseconds.

30000

CT_MAX_PAGE_SIZE

Maximum page size cap.

200

MCP_TRANSPORT_TYPE

Transport: stdio or http.

stdio

MCP_HTTP_PORT

Port for HTTP server.

3010

MCP_AUTH_MODE

Auth mode: none, jwt, or oauth.

none

MCP_LOG_LEVEL

Log level (RFC 5424).

info

LOGS_DIR

Directory for log files (Node.js only).

<project-root>/logs

OTEL_ENABLED

Enable OpenTelemetry tracing.

false

See .env.example for the full list of optional overrides.

Running the server

Local development

  • Build and run:

    # One-time build
    bun run rebuild
    
    # Run the built server
    bun run start:http
    # or
    bun run start:stdio
  • Run checks and tests:

    bun run devcheck   # Lint, format, typecheck, and security audit
    bun run test       # Vitest test suite
    bun run lint:mcp   # Validate MCP definitions against spec

Docker

docker build -t clinicaltrialsgov-mcp-server .
docker run --rm -p 3010:3010 clinicaltrialsgov-mcp-server

The Dockerfile defaults to HTTP transport, stateless session mode, and logs to /var/log/clinicaltrialsgov-mcp-server. OpenTelemetry peer dependencies are installed by default — build with --build-arg OTEL_ENABLED=false to omit them.

Project structure

Directory

Purpose

src/index.ts

createApp() entry point — registers tools/resources/prompts and inits the ClinicalTrials.gov service.

src/config

Server-specific environment variable parsing and validation with Zod.

src/mcp-server/tools

Tool definitions (*.tool.ts).

src/mcp-server/resources

Resource definitions (*.resource.ts).

src/mcp-server/prompts

Prompt definitions (*.prompt.ts).

src/services/clinical-trials

ClinicalTrials.gov REST API v2 client — retry, rate limiting, field search, types.

tests/

Unit and integration tests.

Development guide

See CLAUDE.md for development guidelines and architectural rules. The short version:

  • Handlers throw, framework catches — no try/catch in tool logic

  • Use ctx.log for request-scoped logging, no console calls

  • Register new tools and resources via the barrels in src/mcp-server/*/definitions/index.ts

  • Validate raw API responses, normalize to domain types, and never fabricate missing fields

Contributing

Issues are welcome. Run checks and tests before submitting:

bun run devcheck
bun run test

License

Apache-2.0 — see LICENSE for details.

Available Tools

7 tools
clinicaltrials_find_eligibleClinicaltrials Find EligibleA
Read-onlyIdempotent
Inspect

Match patient demographics and conditions to eligible recruiting clinical trials. Provide age, sex, conditions, and location to find studies with matching eligibility criteria, contact information, and recruiting locations. Results are re-ranked so studies whose own condition matches a requested condition surface above tangential matches from ClinicalTrials.gov's fuzzy condition search. Each candidate returns only the sites matching the requested location (capped by locationLimit), not the study's full registered site list — a large trial can register hundreds of sites worldwide. When none of a candidate's matched sites is recruiting, its nearest recruiting site is added, so an enrollable site is never hidden behind a closer closed one. Fetch a study's complete record with clinicaltrials_get_study_record.

ParametersJSON Schema
NameRequiredDescriptionDefault
ageYesPatient age in years.
sexYesPatient's biological sex. Use 'ALL' to include studies regardless of sex restrictions.
locationYesPatient location as `{ country (required), state?, city? }`. Country is required; state/city narrow the match. For radius-based geographic search, use clinicaltrials_search_studies with geoFilter.
conditionsYesMedical conditions or diagnoses, e.g. ["Type 2 Diabetes", "Hypertension"]. Each entry is matched as a condition (multi-word entries match as a phrase); multiple entries are combined with OR, so studies for any listed condition qualify. Returned studies are re-ranked so those whose own condition list names a requested condition rank above tangential matches the upstream fuzzy search pulls in via the MeSH umbrella.
maxResultsNoMaximum results to return.
locationLimitNoCap on the sites returned per candidate. Each candidate keeps only the sites matching the requested location at the narrowest level that matched (city, else state, else country), capped at this many; the rest of the study's registered sites are omitted. The cap governs those matched sites — when none of them is recruiting, the candidate's nearest recruiting site is added on top of it, so a candidate can carry one site more than this. Raise it to see more nearby sites, or fetch the complete site list with clinicaltrials_get_study_record. Each candidate reports totalLocations / matchedLocations / locationsTruncated / nearestRecruitingSiteAdded in locationSummary only when the bound actually dropped sites.
recruitingOnlyNoOnly include actively recruiting studies.
healthyVolunteerNoWhether the patient is a healthy volunteer. When true, only studies accepting healthy volunteers are queried.

Output Schema

ParametersJSON Schema
NameRequiredDescription
errorNoPresent when the call failed. Absent on success.
funnelNoMatch counts at each filter stage. Shows where the funnel collapsed — e.g., conditionMatched=298 but demographicsMatched=2 means age/sex/status are the constraint.
noticeNoRecovery guidance when no studies matched — identifies which filter stage collapsed and suggests how to broaden. Absent when results are returned.
studiesNoMatching studies with eligibility and location fields. Each candidate's protocolSection.contactsLocationsModule.locations is BOUNDED to the sites matching the requested location (capped at locationLimit) plus, when none of those is recruiting, the candidate's nearest recruiting site — not the study's full registered site list. A candidate whose sites were bounded also carries a top-level locationSummary object — { totalLocations, matchedLocations, locationsTruncated, nearestRecruitingSiteAdded?, retrieveFullStudyWith } — absent when nothing was dropped; nearestRecruitingSiteAdded is present only when that extra site was added. Fetch a study's complete record and site list with clinicaltrials_get_study_record.
totalCountNoTotal matching studies from the API.
searchCriteriaNoNormalized search criteria applied to this eligibility query, including the exact upstream query strings needed to reproduce the full match set via clinicaltrials_search_studies (replay with includeUnknownEnrollment=true, which find_eligible always sets).

TDQS

A4.5/5.0
Behavior5/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Beyond the read-only, open-world, idempotent annotations, the description explains re-ranking of matching conditions, per-candidate site filtering capped by locationLimit, omission of non-matching registered sites, fallback inclusion of a nearest recruiting site, and conditional locationSummary fields. These details give the agent rich behavioral context not available in annotations.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is front-loaded with the core purpose and then proceeds through matching, ranking, site filtering, fallback behavior, and an alternative tool. Despite its length, every sentence addresses behavior an agent needs for this complex, multi-parameter eligibility matching tool.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness5/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given the 8-parameter schema, nested location object, annotations, and output schema, the description is complete. It covers purpose, input expectations, ranking, site truncation, fallback recruiting-site behavior, and when to fetch complete records elsewhere, leaving no critical gap for correct invocation.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, so the baseline is 3. The description reinforces some parameter semantics such as condition matching and locationLimit truncation behavior, but these are already fully documented in the schema, so it does not add significantly more meaning beyond the structured fields.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The first sentence states a specific verb and resource: matching patient demographics and conditions to eligible recruiting clinical trials. It distinguishes the tool from siblings by naming clinicaltrials_get_study_record for full records and clinicaltrials_search_studies with geoFilter for radius searches.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines4/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description clearly says to provide age, sex, conditions, and location to find matching studies, and it routes to alternatives for complete records and radius-based geographic search. However, it does not explicitly state when this tool should be preferred over a general condition search or when patient demographics are insufficient.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

clinicaltrials_get_field_definitionsClinicaltrials Get Field DefinitionsA
Read-onlyIdempotent
Inspect

Resolve valid field names from the ClinicalTrials.gov data model — the canonical PascalCase identifiers (OverallStatus, EnrollmentCount, LeadSponsorName) accepted by the fields, advancedFilter, and sort parameters of other tools, and as input to clinicaltrials_get_field_values. Select a mode: "search" — keyword search returning ranked matches (pass query, e.g. "enrollment", "sponsor", "adverse events"); "drill" — drill into a specific section by dot-notation path (pass path, e.g. "protocolSection.designModule"); "overview" — top-level summary of all sections (no additional args).

ParametersJSON Schema
NameRequiredDescriptionDefault
modeYesOperation mode. "search" — keyword search (requires `query`); "drill" — drill into a section by path (requires `path`); "overview" — list all top-level sections (no other args needed).
pathNodrill mode only. Dot-notation path to drill into — e.g., "protocolSection.designModule", "protocolSection.eligibilityModule", "resultsSection". Returns the section's individual fields.
limitNosearch mode only. Maximum results to return. Default: 20.
queryNosearch mode only. Keyword to search field names by — e.g., "enrollment", "sponsor", "adverse events". Returns matching field names ranked by relevance with their full paths and data types.
includeIndexedOnlyNodrill mode only. Only return indexed (searchable) fields. Default: false.

Output Schema

ParametersJSON Schema
NameRequiredDescription
capNoThe limit cap applied to this search (search mode only).
errorNoPresent when the call failed. Absent on success.
shownNoNumber of fields returned (search mode only).
fieldsNoField definitions, ordered by relevance when mode is "search".
noticeNoRecovery guidance when search mode returns no matches, or a truncation note when results are capped.
truncatedNoTrue when the field list was capped by the limit parameter (search mode only).
searchQueryNoEcho of the keyword used in search mode. Absent for drill and overview.
totalFieldsNoTotal fields returned.
resolvedPathNoResolved path when mode is "drill".
totalMatchesNoTotal fields matching the query before the limit cap was applied (search mode only). Compare against `shown` to size a follow-up limit, or to see that a capped result set is barely over the cap rather than hundreds deep.

TDQS

A4.4/5.0
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnlyHint, idempotentHint, and openWorldHint, so the safety profile is covered. The description adds behavioral value by describing what each mode returns — ranked matches, drilled section fields, top-level section summary — and by noting argument preconditions per mode. Minor gap: no pagination or truncation caveat for `limit`.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Front-loaded with the core purpose before mode mechanics, and every sentence carries information — examples, downstream consumers, mode preconditions. Dense paragraph rather than scannable mode list, which costs a point.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness5/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

With an output schema present, return values need not be explained, and the description still covers the ambiguity that matters (which mode to use, what each requires). An agent has everything needed to select and invoke the tool correctly.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, so every parameter (mode, path, query, limit, includeIndexedOnly) is already documented in the schema, including the same query and path examples. The description restates the mode-to-arg mapping without adding syntax or format detail beyond the schema, so baseline 3 applies.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

States a specific verb (resolve) and resource (valid field names from the ClinicalTrials.gov data model) and pins down the exact artifact returned — canonical PascalCase identifiers like OverallStatus and EnrollmentCount. It also names where those identifiers matter (the `fields`, `advancedFilter`, and `sort` parameters of other tools), which cleanly separates it from the search/record siblings.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines5/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

Gives explicit routing for each mode: use `search` for keyword lookup with a query example, `drill` for section traversal with a path example, and `overview` when no additional args are needed. It further identifies downstream consumers (clinicaltrials_get_field_values) and the sibling parameters that accept the resolved names, so an agent knows both when and why to call it.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

clinicaltrials_get_field_valuesClinicaltrials Get Field ValuesA
Read-onlyIdempotent
Inspect

Discover valid values for ClinicalTrials.gov fields with study counts per value. Use to explore available filter options before building a search — e.g., valid OverallStatus, Phase, InterventionType, StudyType, or LeadSponsorClass values.

ParametersJSON Schema
NameRequiredDescriptionDefault
fieldsYesPascalCase field name(s) to get value statistics for — an empty list is rejected, not treated as "every field". Examples: OverallStatus, Phase, StudyType, Sex, LeadSponsorClass. Use clinicaltrials_get_field_definitions with a query to find more field names.

Output Schema

ParametersJSON Schema
NameRequiredDescription
errorNoPresent when the call failed. Absent on success.
fieldStatsNoOne entry per requested field: canonical path, PascalCase piece name, data type, and the statistics variant that type carries — top values with study counts plus unique/longest for ENUM/STRING, trueCount/falseCount for BOOLEAN, min/max/avg for INTEGER/NUMBER, min/max/formats for DATE.

TDQS

A3.8/5.0
Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnlyHint, idempotentHint and openWorldHint, covering the safety profile. The description adds one behavioral detail beyond that — results are aggregated with per-value study counts — but says nothing about result size, pagination, or whether values are exhaustive for a field.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Two tight sentences: purpose first, then the action-oriented usage note with inline examples. No filler and the most important framing (explore before searching) is front-loaded.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

With an output schema present, the description needn't explain return values, and it correctly focuses on purpose and usage. It is complete enough to invoke correctly; only cross-tool routing to the field-definitions sibling is absent.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, so the schema already documents the single 'fields' parameter, including PascalCase format, examples, and the empty-list rejection. The description's example field list (OverallStatus, Phase, etc.) duplicates the schema's own examples, adding no new meaning.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description states a specific verb and resource ('Discover valid values for ClinicalTrials.gov fields') and even discloses the return payload ('study counts per value'). It distinguishes itself contextually by framing usage 'before building a search', but never names the sibling tools (e.g. clinicaltrials_get_field_definitions or clinicaltrials_search_studies) to sharpen the boundary.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines4/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

It gives clear situational guidance: 'Use to explore available filter options before building a search.' That tells the agent when to reach for it, but it offers no exclusion conditions and does not name the alternative tool (clinicaltrials_get_field_definitions) that also deals with field names.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

clinicaltrials_get_study_countClinicaltrials Get Study CountA
Read-onlyIdempotent
Inspect

Get total clinical trial study count from ClinicalTrials.gov matching a query, without fetching study data. Fast and lightweight. Use for quick statistics or to build breakdowns by calling multiple times with different filters (e.g., count by phase, count by status, count recruiting vs completed for a condition).

ParametersJSON Schema
NameRequiredDescriptionDefault
queryNoGeneral free-text search across all fields. Runs the 57-field relevance search ClinicalTrials.gov publishes for this parameter — NCTId, NCTIdAlias, OrgStudyId, SecondaryId, Acronym, BriefTitle, OfficialTitle, Condition, InterventionName, InterventionOtherName, Phase, StdAge, StudyType, BriefSummary, outcome measures and their descriptions, LeadSponsorName, CollaboratorName, the Location* fields, the Design* fields, and the ConditionAncestorTerm/InterventionAncestorTerm MeSH umbrellas — so a hit need not carry your term in the field you had in mind. Plain words plus AND, OR, NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression — those work here as well as in advancedFilter, so AREA[Phase]PHASE2 is accepted in this parameter; a stray bracket fails. `( )` group sub-expressions and work when matched; `,` acts as AND. The dedicated *Query parameters (conditionQuery, interventionQuery, etc.) scope a search to one field.
titleQueryNoSearch within study titles and acronyms only. Matches Acronym, BriefTitle, and OfficialTitle. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
phaseFilterNoFilter by trial phase. Omit to count all phases — an empty list is rejected, not treated as "no filter". Values: EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA.
outcomeQueryNoSearch within outcome measure fields. Matches PrimaryOutcomeMeasure, SecondaryOutcomeMeasure, OtherOutcomeMeasure, and OutcomeMeasureTitle, plus their description counterparts PrimaryOutcomeDescription, SecondaryOutcomeDescription, OtherOutcomeDescription, OutcomeMeasureDescription, and OutcomeMeasurePopulationDescription — so a term appearing only in outcome prose still matches. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
sponsorQueryNoSponsor/collaborator name search. Matches LeadSponsorName, CollaboratorName, and OrgFullName. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
statusFilterNoFilter by study status. Omit to count all statuses — an empty list is rejected, not treated as "no filter". Values: RECRUITING, COMPLETED, ACTIVE_NOT_RECRUITING, NOT_YET_RECRUITING, ENROLLING_BY_INVITATION, SUSPENDED, TERMINATED, WITHDRAWN, UNKNOWN, WITHHELD, NO_LONGER_AVAILABLE, AVAILABLE, APPROVED_FOR_MARKETING, TEMPORARILY_NOT_AVAILABLE.
locationQueryNoLocation search — city, state, country, or facility name. Matches LocationCity, LocationState, LocationCountry, LocationFacility, and LocationZip; a study matches when any of its sites does. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
advancedFilterNoAdvanced filter using AREA[FieldName]value syntax. Examples: "AREA[StudyType]INTERVENTIONAL", "AREA[EnrollmentCount]RANGE[100, 1000]", "AREA[Phase]PHASE2 AND AREA[StudyType]INTERVENTIONAL", "(AREA[Phase]PHASE3 OR AREA[Phase]PHASE4) AND AREA[StudyType]INTERVENTIONAL". AND/OR/NOT join complete AREA[FieldName]value expressions; parentheses group them. Call clinicaltrials_get_field_definitions to find AREA[]-compatible field names.
conditionQueryNoCondition/disease-specific search. E.g., "Type 2 Diabetes", "non-small cell lung cancer". Matches Condition, BriefTitle, OfficialTitle, ConditionMeshTerm, ConditionAncestorTerm, Keyword, and NCTId. ConditionAncestorTerm is the MeSH umbrella above the conditions a study itself lists, so results run broader than those lists — a study can match a parent term it never names. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
interventionQueryNoIntervention/treatment search. E.g., "pembrolizumab", "cognitive behavioral therapy". Matches InterventionName, InterventionType, ArmGroupType, InterventionOtherName, BriefTitle, OfficialTitle, ArmGroupLabel, InterventionMeshTerm, Keyword, InterventionAncestorTerm, InterventionDescription, and ArmGroupDescription. InterventionAncestorTerm is the MeSH umbrella above the interventions a study itself lists, so results run broader than those lists. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
includeUnknownEnrollmentNoInclude studies whose EnrollmentCount is the upstream "unknown" sentinel (99999999). Excluded by default — the sentinel pollutes RANGE[N, MAX] queries. Set true for data-quality audits.

Output Schema

ParametersJSON Schema
NameRequiredDescription
errorNoPresent when the call failed. Absent on success.
noticeNoRecovery guidance when totalCount is 0 — suggests how to broaden the query or filters.
totalCountNoTotal studies matching the query/filters.
searchCriteriaNoEcho of active query/filter criteria applied to this count, including sentinelFilterActive when the default unknown-enrollment exclusion is in effect.

TDQS

A4.2/5.0
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnlyHint, openWorldHint, and idempotentHint. The description adds behavioral value by noting it is 'Fast and lightweight' and 'without fetching study data,' and by suggesting repeated calls with different filters, which reinforces safe, side-effect-free usage. No contradiction with annotations.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Three sentences with no filler. The core purpose is front-loaded, followed by concrete use cases. Every sentence earns its place, and the description is appropriately sized for the tool's simplicity.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given the tool's complexity (11 optional parameters), the rich schema descriptions, and the presence of an output schema, the description is largely complete. It covers the main use cases and distinguishes the tool from siblings. It does not explicitly mention that calling with no filters returns the overall total, but the schema's optional parameters and the phrase 'matching a query' make that inferable.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, so the schema already documents all 11 parameters in detail. The description adds only high-level examples of filters ('phase, status, condition') that map to existing parameters, but no new semantic meaning beyond the schema. Baseline 3 is appropriate.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description states a specific verb and resource: 'Get total clinical trial study count from ClinicalTrials.gov matching a query.' It also distinguishes itself from sibling tools by explicitly saying 'without fetching study data,' which separates it from search/record tools. The use-case framing ('quick statistics', 'breakdowns') further clarifies its unique role.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines4/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description gives clear context for when to use it: 'Use for quick statistics or to build breakdowns by calling multiple times with different filters.' It implies the alternative (fetching study data) is not this tool's purpose, but it does not explicitly name sibling tools or state when not to use it. This is clear guidance with no exclusions, but not fully explicit.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

clinicaltrials_get_study_recordClinicaltrials Get Study RecordA
Read-onlyIdempotent
Inspect

Fetch a single clinical trial study by NCT ID from ClinicalTrials.gov. Returns the full study record including protocol details, eligibility criteria, outcomes, arms, interventions, contacts, and locations. Optional locationLimit / outcomeLimit / referenceLimit / nearLocation parameters trim locations, outcomes, and references — original totals are preserved in filtersApplied only when a cap actually trims the set.

ParametersJSON Schema
NameRequiredDescriptionDefault
nctIdYesNCT identifier — format `NCT` followed by 8 digits (e.g., `NCT03722472`).
nearLocationNoFilter returned locations to those within radius of (lat, lon) and sort by distance. Adds distanceMi to each location. Locations without published coordinates are dropped — most US sites carry them; international sites less reliably so. Distances reflect ClinicalTrials.gov geocoding granularity — typically city-centroid, not facility-level — so multiple sites in the same city resolve to near-identical distances. For broader geographic filtering across studies, use clinicaltrials_search_studies with geoFilter.
outcomeLimitNoOptional cap on the number of secondary and other outcomes returned. Omit for no cap (full upstream lists). Primary outcomes are never capped. Original totals preserved in filtersApplied.totalSecondaryOutcomes / totalOtherOutcomes only when the cap trims a list.
locationLimitNoOptional cap on the number of locations returned. Omit for no cap (full upstream list). Pairs naturally with nearLocation for narrowing a large multi-site trial. Original total preserved in filtersApplied.totalLocations only when the cap trims the list.
referenceLimitNoOptional cap on the number of references returned. Omit for no cap (full upstream list). Original total preserved in filtersApplied.totalReferences only when the cap trims the list. seeAlsoLinks are never capped.

Output Schema

ParametersJSON Schema
NameRequiredDescription
errorNoPresent when the call failed. Absent on success.
studyNoFull study record with caller-requested filters already applied to locations and outcomes. Top-level keys: protocolSection (identification, status, sponsor, conditions, design, arms/interventions, outcomes, eligibility, contacts/locations), derivedSection (MeSH-normalized terms), hasResults, documentSection. The heavy resultsSection is omitted — see resultsSummary for counts and clinicaltrials_get_study_results for full results data. Use clinicaltrials_get_field_definitions to explore the schema.
filtersAppliedNoMetadata about the filtering applied to `study`.
resultsSummaryNoCompact counts of posted results, present when hasResults is true. The full resultsSection is intentionally omitted from this record-level tool — fetch it via clinicaltrials_get_study_results or the clinicaltrials://{nctId} resource.

TDQS

A4.5/5.0
Behavior5/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Adds meaningfully beyond the readOnly/openWorld/idempotent annotations: explains that caps preserve original totals in filtersApplied only when a list is actually trimmed, that primary outcomes and seeAlsoLinks are never capped, and that nearLocation geocoding is city-centroid and drops locations without coordinates. This is exactly the kind of non-obvious runtime behavior an agent needs.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Two front-loaded sentences with no filler: first states the primary purpose, second captures the one non-obvious behavioral subtlety about caps and filtersApplied. The prose is dense but every clause adds value.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness5/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

The output schema handles return-value expectations, the param schema thoroughly documents behavior, annotations cover safety and idempotency, and the description adds scope, cap semantics, and geocoding limitations. For an agent deciding whether and how to call this tool, nothing meaningful is missing.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, and every parameter already has a thorough description including ranges, defaults, and behavior. The tool description itself adds little beyond a concise summary of the trimming behavior, so the baseline score of 3 is appropriate.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

Starts with a specific verb and resource: 'Fetch a single clinical trial study by NCT ID'. Unambiguously distinguishes this from sibling tools like the search/count tools, and the 'by NCT ID' identifier makes the invocation target crystal clear.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines4/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description makes clear this is the tool for fetching one study by NCT ID, and the nearLocation parameter description explicitly points to clinicaltrials_search_studies for broad geographic filtering. However, it does not directly contrast with all relevant siblings such as clinicaltrials_get_study_results, so the routing guidance is good but not exhaustive.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

clinicaltrials_get_study_resultsClinicaltrials Get Study ResultsA
Read-onlyIdempotent
Inspect

Fetch clinical trial results data from ClinicalTrials.gov for completed studies — outcome measures with statistics, adverse events, participant flow, baseline characteristics, and results metadata (limitations & caveats, certain-agreement disclosure restrictions, results point of contact). Only available for studies where hasResults is true. Use clinicaltrials_search_studies first to find studies with results. A results-rich record can exceed 500KB per study in full mode — bound it with summary=true, narrower sections, or the outcomeLimit / adverseEventLimit caps. A bounded list is resumable: outcomeOffset / seriousEventOffset / otherEventOffset start the next window, and each study's filtersApplied reports what was trimmed and the next offset for every list left short. A previous (alias) NCT ID resolves to its canonical study, named in canonicalNctId.

ParametersJSON Schema
NameRequiredDescriptionDefault
nctIdsYesOne or more NCT IDs (max 20) — an empty list is rejected, and a repeated ID collapses to one results entry in first-occurrence order. E.g., "NCT12345678" or ["NCT12345678", "NCT87654321"]. Use summary=true for large batches to avoid large payloads.
summaryNoReturn condensed summaries instead of full data. Full mode renders every row and field on both output channels, so a large results set can exceed 500KB per study; summary mode typically cuts that to a few KB, scaling with the measure count rather than to a fixed ceiling. An outcome summary keeps the title, type, timeframe, paramType, dispersionType, unit, group/class counts, per-group denominators, one statistical analysis, and a top-line projection of a single class/category cell — labelled with the class and category titles it came from and a count of the siblings it omits. The measurements outside that cell and the remaining analyses are dropped; re-run with summary=false to reach them. For a middle ground, keep full mode and cap the two lists that carry the bulk with outcomeLimit / adverseEventLimit.
sectionsNoFilter which sections to return. Values: outcomes, adverseEvents, participantFlow, baseline, moreInfo. Omit for all sections — an empty list is rejected, not treated as omission.
outcomeLimitNoOptional cap on the number of outcome measures returned per study, taken in the order ClinicalTrials.gov publishes them. Omit for no cap (every measure). Applies to full mode only — summary mode is already condensed. Each surviving measure keeps its complete groups/classes/measurements/analyses tree. Upstream total preserved in filtersApplied.totalOutcomes only when the cap trims the list.
outcomeOffsetNoOptional index of the first outcome measure to return, in the order ClinicalTrials.gov publishes them. Omit or 0 to start at the first. Pair with outcomeLimit to page a long list: each response reports filtersApplied.nextOutcomeOffset for the study, and the list is exhausted when that field is absent. Applied to every study in the call. An offset at or past the end returns an empty list with filtersApplied.totalOutcomes stating the upstream length, not an error. Rejected with summary: true or when sections excludes outcomes.
otherEventOffsetNoOptional index of the first other (non-serious) adverse event to return, in upstream order. Omit or 0 to start at the first. Pages independently of seriousEventOffset and pairs with adverseEventLimit. Continue from filtersApplied.nextOtherEventOffset until that field is absent. Applied to every study in the call. Rejected with summary: true or when sections excludes adverseEvents.
adverseEventLimitNoOptional cap on the number of serious and other adverse events returned per study, applied to each list separately in upstream order. Omit for no cap (every event). Applies to full mode only — summary mode already ranks the top 20 by participants affected. Event groups are never capped. Upstream totals preserved in filtersApplied.totalSeriousEvents / totalOtherEvents only when the cap trims a list.
seriousEventOffsetNoOptional index of the first serious adverse event to return, in upstream order. Omit or 0 to start at the first. Pages independently of otherEventOffset — the two lists have uncorrelated lengths — and pairs with adverseEventLimit, which bounds each list separately. Continue from filtersApplied.nextSeriousEventOffset until that field is absent. Applied to every study in the call. Rejected with summary: true or when sections excludes adverseEvents.

Output Schema

ParametersJSON Schema
NameRequiredDescription
errorNoPresent when the call failed. Absent on success.
resultsNoResults per study.
truncatedNoTrue when a bound — a cap or an offset — trimmed a list on at least one study; absent when nothing was trimmed, matching filtersApplied one level down. Which study, which list, and where to resume is named in that study’s filtersApplied.
fetchErrorsNoStudies that could not be fetched.
studiesWithoutResultsNoNCT IDs that do not have results data.

TDQS

A4.4/5.0
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already cover the safety profile (readOnly/idempotent/openWorld), but the description adds real behavioral context: payload-size risk (>500KB per study), resumability via offsets, filtersApplied reporting of what was trimmed, and alias-to-canonical NCT resolution. Some of this overlaps the parameter descriptions rather than being purely new, so it falls just short of a 5.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Purpose and availability condition are front-loaded, and the remaining sentences each carry distinct operational value (size limits, bounding, pagination, alias handling). It is dense but slightly long, with a few clauses that restate schema-level detail.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness5/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

For an 8-parameter, multi-section tool with an output schema, the description covers everything an agent needs: the hasResults gate, the discovery prerequisite, size-mitigation options, pagination/resume mechanics, and alias canonicalization. Return-value structure is correctly left to the output schema.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100% and the schema itself is highly detailed on every parameter, including offset/limit pairing. The description reinforces the same points (narrower sections, caps, resume offsets) but adds no semantics not already in the schema, so the baseline 3 applies.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

States a specific verb (fetch) and resource (clinical trial results data) and enumerates the payload contents (outcome measures, adverse events, participant flow, baseline characteristics, results metadata). It implicitly distinguishes itself from clinicaltrials_get_study_record by scoping strictly to results data and the hasResults precondition.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines5/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

Gives an explicit precondition (only available where hasResults is true) plus a concrete routing instruction: 'Use clinicaltrials_search_studies first to find studies with results.' It also names the bounding alternatives (summary=true, narrower sections, outcomeLimit/adverseEventLimit) which is genuine when-to-use guidance.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

clinicaltrials_search_studiesClinicaltrials Search StudiesA
Read-onlyIdempotent
Inspect

Search for clinical trial studies from ClinicalTrials.gov. Supports full-text and field-specific queries, status/phase/geographic filters, pagination, sorting, and field selection. Returns a compact per-study index by default; pass the fields parameter to get specific leaves at full fidelity — full study records are ~70KB each.

ParametersJSON Schema
NameRequiredDescriptionDefault
sortNoSort order. Format: FieldName:asc or FieldName:desc. E.g., "LastUpdatePostDate:desc", "EnrollmentCount:desc". Max 2 fields comma-separated. For "largest trials" queries, pair EnrollmentCount:desc with advancedFilter "AREA[StudyType]INTERVENTIONAL" — the top enrollment counts are observational registry/claims studies enrolling tens of millions. Enrollment counts are sponsor-reported and not validated upstream beyond the unknown-enrollment sentinel exclusion. Use clinicaltrials_get_field_definitions to find sortable field names.
queryNoGeneral free-text search across all fields. Runs the 57-field relevance search ClinicalTrials.gov publishes for this parameter — NCTId, NCTIdAlias, OrgStudyId, SecondaryId, Acronym, BriefTitle, OfficialTitle, Condition, InterventionName, InterventionOtherName, Phase, StdAge, StudyType, BriefSummary, outcome measures and their descriptions, LeadSponsorName, CollaboratorName, the Location* fields, the Design* fields, and the ConditionAncestorTerm/InterventionAncestorTerm MeSH umbrellas — so a hit need not carry your term in the field you had in mind. Plain words plus AND, OR, NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression — those work here as well as in advancedFilter, so AREA[Phase]PHASE2 is accepted in this parameter; a stray bracket fails. `( )` group sub-expressions and work when matched; `,` acts as AND. The dedicated *Query parameters (conditionQuery, interventionQuery, etc.) scope a search to one field.
fieldsNoPascalCase leaf names to return; strongly recommended since full records are ~70KB. Omit for the compact index projection — an empty list is rejected, not treated as omission. Common leaves: NCTId, BriefTitle, BriefSummary, OverallStatus, Phase, LeadSponsorName, Condition. Call clinicaltrials_get_field_definitions with a concept query (e.g., "adverse events", "eligibility") to find the exact leaf for any concept.
nctIdsNoFilter to specific NCT IDs for batch lookups. Omit to search every study — an empty list is rejected, not treated as "no filter". Supplying this lifts the default unknown-enrollment exclusion, so an ID you name is never filtered out of its own lookup.
pageSizeNoResults per page, 1–200.
geoFilterNoGeographic proximity filter. Format: distance(lat,lon,radius), where radius carries a `mi` or `km` suffix — e.g. "distance(47.6062,-122.3321,50mi)" for studies within 50 miles of Seattle. The suffix is required: a radius with no unit is rejected, as are a non-positive radius, a latitude outside [-90, 90], and a longitude outside [-180, 180]. When set, each study's locations are re-sorted by proximity to the center so the nearest matched site leads, annotated with its distance in miles; the full location list is preserved.
pageTokenNoPagination cursor from a previous response.
countTotalNoInclude total study count in response. Only computed on the first page.
titleQueryNoSearch within study titles and acronyms only. Matches Acronym, BriefTitle, and OfficialTitle. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
phaseFilterNoFilter by trial phase. Omit to search all phases — an empty list is rejected, not treated as "no filter". Values: EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA.
outcomeQueryNoSearch within outcome measure fields. Matches PrimaryOutcomeMeasure, SecondaryOutcomeMeasure, OtherOutcomeMeasure, and OutcomeMeasureTitle, plus their description counterparts PrimaryOutcomeDescription, SecondaryOutcomeDescription, OtherOutcomeDescription, OutcomeMeasureDescription, and OutcomeMeasurePopulationDescription — so a term appearing only in outcome prose still matches. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
sponsorQueryNoSponsor/collaborator name search. Matches LeadSponsorName, CollaboratorName, and OrgFullName. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
statusFilterNoFilter by study status. Omit to search all statuses — an empty list is rejected, not treated as "no filter". Values: RECRUITING, COMPLETED, ACTIVE_NOT_RECRUITING, NOT_YET_RECRUITING, ENROLLING_BY_INVITATION, SUSPENDED, TERMINATED, WITHDRAWN, UNKNOWN, WITHHELD, NO_LONGER_AVAILABLE, AVAILABLE, APPROVED_FOR_MARKETING, TEMPORARILY_NOT_AVAILABLE.
locationQueryNoLocation search — city, state, country, or facility name. Matches LocationCity, LocationState, LocationCountry, LocationFacility, and LocationZip; a study matches when any of its sites does. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
advancedFilterNoAdvanced filter using AREA[FieldName]value syntax. Examples: "AREA[StudyType]INTERVENTIONAL", "AREA[EnrollmentCount]RANGE[100, 1000]", "AREA[Phase]PHASE2 AND AREA[StudyType]INTERVENTIONAL", "(AREA[Phase]PHASE3 OR AREA[Phase]PHASE4) AND AREA[StudyType]INTERVENTIONAL". AND/OR/NOT join complete AREA[FieldName]value expressions; parentheses group them. Call clinicaltrials_get_field_definitions to find AREA[]-compatible field names.
conditionQueryNoCondition/disease-specific search. E.g., "Type 2 Diabetes", "non-small cell lung cancer". Matches Condition, BriefTitle, OfficialTitle, ConditionMeshTerm, ConditionAncestorTerm, Keyword, and NCTId. ConditionAncestorTerm is the MeSH umbrella above the conditions a study itself lists, so results run broader than those lists — a study can match a parent term it never names. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
interventionQueryNoIntervention/treatment search. E.g., "pembrolizumab", "cognitive behavioral therapy". Matches InterventionName, InterventionType, ArmGroupType, InterventionOtherName, BriefTitle, OfficialTitle, ArmGroupLabel, InterventionMeshTerm, Keyword, InterventionAncestorTerm, InterventionDescription, and ArmGroupDescription. InterventionAncestorTerm is the MeSH umbrella above the interventions a study itself lists, so results run broader than those lists. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND.
includeUnknownEnrollmentNoInclude studies whose EnrollmentCount is the upstream "unknown" sentinel (99999999). Excluded by default — the sentinel pollutes RANGE[N, MAX] queries and EnrollmentCount:desc sorts. Set true for data-quality audits or when targeting unknown-enrollment studies specifically.

Output Schema

ParametersJSON Schema
NameRequiredDescription
errorNoPresent when the call failed. Absent on success.
noticeNoRecovery guidance when no studies matched — echoes the constraint and suggests how to broaden, and names nctIds as part of the unmatched criteria when an ID list was supplied. Absent on pages with results, and on an exhausted continuation page, where the cohort already matched and there is nothing to broaden.
studiesNoMatching studies. By default each entry is a COMPACT index projection — nctId, briefTitle, overallStatus, phases, enrollmentCount, leadSponsor, conditions, and a bounded locations summary ({ total, nearest }) — mirroring the rendered result, NOT the full ~70KB record. Pass the fields parameter to receive exactly the requested leaves at full fidelity instead (e.g. all locations). Fetch a full single record with clinicaltrials_get_study_record.
totalCountNoTotal matching studies (first page only when countTotal=true).
nextPageTokenNoToken for the next page. Absent when this response already carries every matching study; otherwise it mirrors the upstream cursor, which ClinicalTrials.gov emits whenever a page fills to pageSize — so on a continuation page a token can still lead to an empty page.
pageExhaustedNoTrue when this call supplied a pageToken and the continuation page came back empty — the walk is finished and no further pages exist. Absent on every other response, including an empty first page, which is an unmatched search rather than exhausted pagination.
searchCriteriaNoEcho of active query/filter criteria applied to this search, including sentinelFilterActive when the default unknown-enrollment exclusion is in effect. Present on every response.
requestedFieldsNoEcho of the explicit fields parameter — present only when the caller passed fields. Signals that studies carry the requested leaves at full fidelity (not the default compact index) and that the rendered truncation cap is lifted so all of them appear.

TDQS

A3.8/5.0
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already cover the safety profile (readOnly, idempotent, openWorld), so the description is not obligated to restate them. It adds genuinely useful behavioral context the annotations do not: the default compact projection, the ~70KB full-record size warning, and the fact that fields unlocks full-fidelity leaves — all of which shape how an agent calls it. It stops short of auth, rate limits, or pagination behavior.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Three sentences, each earning its place: purpose first, capability scope second, and the high-value return-size caveat last. Front-loaded and free of filler despite the tool's 18-parameter surface.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

With an output schema present, return values need not be explained in prose, and the 100% schema coverage means parameter semantics are handled elsewhere. The description covers purpose, default projection, and the size trap; the only remaining gap is guidance on when a search is the right call versus the record/count/eligibility siblings.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema coverage is 100% and the parameter descriptions are exceptionally rich (search-field enumerations, syntax rules, sentinel-enrollment handling, unit requirements for geoFilter), so the schema carries the semantic burden. The top-level description only briefly reinforces the fields parameter and adds no parameter meaning beyond what the schema already states — baseline 3 applies.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

Names a specific verb and resource ("Search for clinical trial studies from ClinicalTrials.gov") and enumerates the query/filter capabilities. The mention of returning a "compact per-study index by default" implicitly separates it from clinicaltrials_get_study_record, but no sibling is named, so differentiation is inferential rather than explicit.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines3/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

Usage is implied by "Search for clinical trial studies" plus the default-return note, which nudges the agent toward the fields parameter. However, there is no explicit when-to-use statement, no exclusion of cases better served by clinicaltrials_get_study_count, clinicaltrials_get_study_record, or clinicaltrials_find_eligible, and no prerequisites.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

Tool Schema Changelog

Recent tool additions, removals, and schema changes observed during successful MCP inspections.

  1. 5 tool updatesv2.9.6
    • Changedclinicaltrials_find_eligible1 field changed
      • changedOutput schema / properties / searchCriteria / properties / location / description
        Previous value: -"The exact queryLocn string sent upstream (city/state/country joined). Pass as locationQuery to clinicaltrials_search_studies to reproduce the location filter beyond the maxResults cap."New value: +"The exact queryLocn string sent upstream (city/state/country, multi-word components quoted, AND-joined). Pass as locationQuery to clinicaltrials_search_studies to reproduce the location filter beyond the maxResults cap."
    • Changedclinicaltrials_get_field_definitions2 fields changed
      • changedOutput schema / properties / error / properties / data / properties / reason / description
        Previous value: -"Machine-readable failure mode. Declared by this tool: `path_not_found`: The dot-notation path does not match any node in the field tree. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler."New value: +"Machine-readable failure mode. Declared by this tool: `blank_value`: The selected mode's required argument was supplied with a whitespace-only value. `mode_mismatch`: An argument belonging to a different mode was supplied alongside the selected mode. `mode_requires`: The selected mode's required argument was omitted. `path_not_found`: The dot-notation path does not match any node in the field tree. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler."
      • changedOutput schema / properties / error / properties / data / properties / reason / examples
        Previous value: -[
        -  "path_not_found",
        -  "rate_limited"
        -]New value: +[
        +  "blank_value",
        +  "mode_mismatch",
        +  "mode_requires",
        +  "path_not_found",
        +  "rate_limited"
        +]
    • Changedclinicaltrials_get_field_values7 fields changed
      • changedOutput schema / properties / fieldStats / description
        Previous value: -"One entry per requested field: canonical path, PascalCase piece name, data type, missing/unique counts, and top values with study counts (or trueCount/falseCount for BOOLEAN fields)."New value: +"One entry per requested field: canonical path, PascalCase piece name, data type, and the statistics variant that type carries — top values with study counts plus unique/longest for ENUM/STRING, trueCount/falseCount for BOOLEAN, min/max/avg for INTEGER/NUMBER, min/max/formats for DATE."
      • addedOutput schema / properties / fieldStats / items / properties / avg
        Added value: +{
        +  "description": "Mean of the recorded values. Present for INTEGER/NUMBER fields.",
        +  "type": "number"
        +}
      • addedOutput schema / properties / fieldStats / items / properties / formats
        Added value: +{
        +  "description": "Date patterns this field is recorded in. Present for DATE fields; more than one means the field mixes precisions across studies.",
        +  "items": {
        +    "description": "A date pattern, e.g. \"yyyy-MM-dd\".",
        +    "type": "string"
        +  },
        +  "type": "array"
        +}
      • addedOutput schema / properties / fieldStats / items / properties / longest
        Added value: +{
        +  "additionalProperties": false,
        +  "description": "Longest recorded value with its length and a study carrying it. Present for STRING fields only.",
        +  "properties": {
        +    "length": {
        +      "description": "Its length in characters.",
        +      "type": "number"
        +    },
        +    "nctId": {
        +      "description": "NCT ID of a study carrying it.",
        +      "type": "string"
        +    },
        +    "value": {
        +      "description": "The longest recorded value.",
        +      "type": "string"
        +    }
        +  },
        +  "required": [
        +    "value",
        +    "length",
        +    "nctId"
        +  ],
        +  "type": "object"
        +}
      • addedOutput schema / properties / fieldStats / items / properties / max
        Added value: +{
        +  "anyOf": [
        +    {
        +      "description": "Largest value of an INTEGER/NUMBER field.",
        +      "type": "number"
        +    },
        +    {
        +      "description": "Latest value of a DATE field, at the precision recorded.",
        +      "type": "string"
        +    }
        +  ],
        +  "description": "Largest recorded value — a number for INTEGER/NUMBER, a date string for DATE."
        +}
      • addedOutput schema / properties / fieldStats / items / properties / min
        Added value: +{
        +  "anyOf": [
        +    {
        +      "description": "Smallest value of an INTEGER/NUMBER field.",
        +      "type": "number"
        +    },
        +    {
        +      "description": "Earliest value of a DATE field, at the precision recorded — a partial date such as \"1900-01\" stays partial.",
        +      "type": "string"
        +    }
        +  ],
        +  "description": "Smallest recorded value — a number for INTEGER/NUMBER, a date string for DATE."
        +}
      • changedOutput schema / properties / fieldStats / items / properties / multiValued / description
        Previous value: -"True when the field is array-typed (a study can carry several values, e.g. Phase, Condition), so the per-value studiesCount buckets sum above the study total. Use to avoid computing a percentage against the corpus."New value: +"True when the field is repeated — array-typed itself (Phase, Condition) or nested under a repeated object (LocationCountry, one per site) — so a study can carry several values and the per-value studiesCount buckets sum above the study total. Use to avoid computing a percentage against the corpus."
    • Changedclinicaltrials_get_study_results23 fields changed
      • changedInput schema / properties / nctIds / description
        Previous value: -"One or more NCT IDs (max 20) — an empty list is rejected. E.g., \"NCT12345678\" or [\"NCT12345678\", \"NCT87654321\"]. Use summary=true for large batches to avoid large payloads."New value: +"One or more NCT IDs (max 20) — an empty list is rejected, and a repeated ID collapses to one results entry in first-occurrence order. E.g., \"NCT12345678\" or [\"NCT12345678\", \"NCT87654321\"]. Use summary=true for large batches to avoid large payloads."
      • addedInput schema / properties / otherEventOffset
        Added value: +{
        +  "description": "Optional index of the first other (non-serious) adverse event to return, in upstream order. Omit or 0 to start at the first. Pages independently of seriousEventOffset and pairs with adverseEventLimit. Continue from filtersApplied.nextOtherEventOffset until that field is absent. Applied to every study in the call. Rejected with summary: true or when sections excludes adverseEvents.",
        +  "maximum": 9007199254740991,
        +  "minimum": 0,
        +  "type": "integer"
        +}
      • addedInput schema / properties / outcomeOffset
        Added value: +{
        +  "description": "Optional index of the first outcome measure to return, in the order ClinicalTrials.gov publishes them. Omit or 0 to start at the first. Pair with outcomeLimit to page a long list: each response reports filtersApplied.nextOutcomeOffset for the study, and the list is exhausted when that field is absent. Applied to every study in the call. An offset at or past the end returns an empty list with filtersApplied.totalOutcomes stating the upstream length, not an error. Rejected with summary: true or when sections excludes outcomes.",
        +  "maximum": 9007199254740991,
        +  "minimum": 0,
        +  "type": "integer"
        +}
      • addedInput schema / properties / seriousEventOffset
        Added value: +{
        +  "description": "Optional index of the first serious adverse event to return, in upstream order. Omit or 0 to start at the first. Pages independently of otherEventOffset — the two lists have uncorrelated lengths — and pairs with adverseEventLimit, which bounds each list separately. Continue from filtersApplied.nextSeriousEventOffset until that field is absent. Applied to every study in the call. Rejected with summary: true or when sections excludes adverseEvents.",
        +  "maximum": 9007199254740991,
        +  "minimum": 0,
        +  "type": "integer"
        +}
      • changedInput schema / properties / summary / description
        Previous value: -"Return condensed summaries instead of full data. Full mode renders every row and field on both output channels, so a large results set can exceed 500KB per study; summary mode reduces that to ~5KB. Summaries include outcome titles, types, timeframes, group counts, and top-level stats — omitting individual measurements, analyses, and per-group data. For a middle ground, keep full mode and cap the two lists that carry the bulk with outcomeLimit / adverseEventLimit."New value: +"Return condensed summaries instead of full data. Full mode renders every row and field on both output channels, so a large results set can exceed 500KB per study; summary mode typically cuts that to a few KB, scaling with the measure count rather than to a fixed ceiling. An outcome summary keeps the title, type, timeframe, paramType, dispersionType, unit, group/class counts, per-group denominators, one statistical analysis, and a top-line projection of a single class/category cell — labelled with the class and category titles it came from and a count of the siblings it omits. The measurements outside that cell and the remaining analyses are dropped; re-run with summary=false to reach them. For a middle ground, keep full mode and cap the two lists that carry the bulk with outcomeLimit / adverseEventLimit."
      • changedOutput schema / properties / error / properties / data / properties / reason / description
        Previous value: -"Machine-readable failure mode. Declared by this tool: `blank_value`: A parameter was supplied with a blank, whitespace-only, or empty-list value. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler."New value: +"Machine-readable failure mode. Declared by this tool: `blank_value`: A parameter was supplied with a blank, whitespace-only, or empty-list value. `offset_not_applicable`: An offset was supplied for a list this call does not return — summary mode returns a condensed projection rather than a bounded window, or the sections filter excludes the offset’s own section. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler."
      • changedOutput schema / properties / error / properties / data / properties / reason / examples
        Previous value: -[
        -  "blank_value",
        -  "rate_limited"
        -]New value: +[
        +  "blank_value",
        +  "offset_not_applicable",
        +  "rate_limited"
        +]
      • addedOutput schema / properties / results / items / properties / canonicalNctId
        Added value: +{
        +  "description": "The canonical NCT identifier of the study that answered — present only when the requested nctId is a previous (alias) ID pointing at a different record. Absent means nctId is already canonical. Requesting an alias and its own canonical ID together returns one entry per requested ID, both carrying the same study.",
        +  "type": "string"
        +}
      • changedOutput schema / properties / results / items / properties / filtersApplied / description
        Previous value: -"What a cap trimmed on this study — present only when a cap actually reduced a list. Absent means the payload is the complete upstream set for the requested sections."New value: +"What the outcomeLimit / adverseEventLimit caps and the outcomeOffset / seriousEventOffset / otherEventOffset offsets trimmed on this study, plus the next offset for each list left short. Present only when a bound actually reduced a list — a window that started at zero and reached the end trimmed nothing. Absent means the payload is the complete upstream set for the requested sections. Offsets apply uniformly to every study in the call, so continuation is reported per study: each exhausts its lists at a different index."
      • changedOutput schema / properties / results / items / properties / filtersApplied / properties / adverseEventLimit / description
        Previous value: -"Echo of the adverseEventLimit input — present only when the cap trimmed a list."New value: +"Echo of the adverseEventLimit input — present only when the cap cut events off the end of a window. Which list it cut is named by that list’s own next offset."
      • addedOutput schema / properties / results / items / properties / filtersApplied / properties / nextOtherEventOffset
        Added value: +{
        +  "description": "The otherEventOffset to request next for this study — present only when other events remain past the window. Absent means this study’s other event list is exhausted.",
        +  "maximum": 9007199254740991,
        +  "minimum": -9007199254740991,
        +  "type": "integer"
        +}
      • addedOutput schema / properties / results / items / properties / filtersApplied / properties / nextOutcomeOffset
        Added value: +{
        +  "description": "The outcomeOffset to request next for this study — present only when measures remain past the window. Absent means this study’s outcome list is exhausted.",
        +  "maximum": 9007199254740991,
        +  "minimum": -9007199254740991,
        +  "type": "integer"
        +}
      • addedOutput schema / properties / results / items / properties / filtersApplied / properties / nextSeriousEventOffset
        Added value: +{
        +  "description": "The seriousEventOffset to request next for this study — present only when serious events remain past the window. Absent means this study’s serious event list is exhausted.",
        +  "maximum": 9007199254740991,
        +  "minimum": -9007199254740991,
        +  "type": "integer"
        +}
      • addedOutput schema / properties / results / items / properties / filtersApplied / properties / otherEventOffset
        Added value: +{
        +  "description": "Echo of the otherEventOffset input — present only when it skipped events before the window.",
        +  "maximum": 9007199254740991,
        +  "minimum": -9007199254740991,
        +  "type": "integer"
        +}
      • changedOutput schema / properties / results / items / properties / filtersApplied / properties / outcomeLimit / description
        Previous value: -"Echo of the outcomeLimit input — present only when the cap trimmed the list."New value: +"Echo of the outcomeLimit input — present only when the cap cut measures off the end of the window."
      • addedOutput schema / properties / results / items / properties / filtersApplied / properties / outcomeOffset
        Added value: +{
        +  "description": "Echo of the outcomeOffset input — present only when it skipped measures before the window.",
        +  "maximum": 9007199254740991,
        +  "minimum": -9007199254740991,
        +  "type": "integer"
        +}
      • addedOutput schema / properties / results / items / properties / filtersApplied / properties / seriousEventOffset
        Added value: +{
        +  "description": "Echo of the seriousEventOffset input — present only when it skipped events before the window.",
        +  "maximum": 9007199254740991,
        +  "minimum": -9007199254740991,
        +  "type": "integer"
        +}
      • changedOutput schema / properties / results / items / properties / filtersApplied / properties / totalOtherEvents / description
        Previous value: -"Upstream other adverse event count before adverseEventLimit trimmed the list."New value: +"Upstream other adverse event count, before the bounds trimmed the list."
      • changedOutput schema / properties / results / items / properties / filtersApplied / properties / totalOutcomes / description
        Previous value: -"Upstream outcome measure count before outcomeLimit trimmed the list."New value: +"Upstream outcome measure count, before the bounds trimmed the list."
      • changedOutput schema / properties / results / items / properties / filtersApplied / properties / totalSeriousEvents / description
        Previous value: -"Upstream serious adverse event count before adverseEventLimit trimmed the list."New value: +"Upstream serious adverse event count, before the bounds trimmed the list."
      • changedOutput schema / properties / results / items / properties / nctId / description
        Previous value: -"NCT identifier."New value: +"The NCT identifier as requested, echoed verbatim. When it is a previous (alias) ID, ClinicalTrials.gov answers with the canonical record and canonicalNctId names it."
      • changedOutput schema / properties / results / items / properties / outcomes / description
        Previous value: -"Outcome measures with per-group statistics. Summary mode (compact): type, title, timeFrame, paramType, unitOfMeasure, group/class counts, plus topStats (per-group measurements) and topAnalysis (statisticalMethod, pValue, paramType/Value, ciPctValue/Lower/Upper, nonInferiorityType, groupIds — lifted from analyses[0]) when present. Full mode (default): adds raw groups, classes, categories, measurements, and analyses arrays."New value: +"Outcome measures with per-group statistics. Summary mode (compact): type, title, timeFrame, paramType, dispersionType, unitOfMeasure, group/class counts, denoms (per-group denominators keyed by group title), topStats (the per-group cells of one class/category — each carrying the upstream value verbatim, including an NA/NR sentinel, plus spread, lowerLimit/upperLimit, and the record’s own comment when present), topStatsFrom (classTitle / categoryTitle naming where that cell came from, with omittedClasses / omittedCategories counts and a note pointing at summary=false when siblings were dropped), and topAnalysis (statisticalMethod, pValue, paramType/Value, ciPctValue/Lower/Upper, nonInferiorityType, groupIds — lifted from analyses[0]) when present. Full mode (default): adds raw groups, classes, categories, measurements, and analyses arrays."
      • changedOutput schema / properties / truncated / description
        Previous value: -"True when a cap trimmed a list on at least one study; absent when nothing was trimmed, matching filtersApplied one level down. Which study and which list is named in that study’s filtersApplied."New value: +"True when a bound — a cap or an offset — trimmed a list on at least one study; absent when nothing was trimmed, matching filtersApplied one level down. Which study, which list, and where to resume is named in that study’s filtersApplied."
    • Changedclinicaltrials_search_studies3 fields changed
      • changedInput schema / properties / geoFilter / description
        Previous value: -"Geographic proximity filter. Format: distance(lat,lon,radius), where radius carries a `mi` or `km` suffix — e.g. \"distance(47.6062,-122.3321,50mi)\" for studies within 50 miles of Seattle. Always include the suffix: a bare radius is accepted upstream but interpreted as meters, which silently matches almost nothing. When set, each study's locations are re-sorted by proximity to the center so the nearest matched site leads, annotated with its distance in miles; the full location list is preserved."New value: +"Geographic proximity filter. Format: distance(lat,lon,radius), where radius carries a `mi` or `km` suffix — e.g. \"distance(47.6062,-122.3321,50mi)\" for studies within 50 miles of Seattle. The suffix is required: a radius with no unit is rejected, as are a non-positive radius, a latitude outside [-90, 90], and a longitude outside [-180, 180]. When set, each study's locations are re-sorted by proximity to the center so the nearest matched site leads, annotated with its distance in miles; the full location list is preserved."
      • changedOutput schema / properties / notice / description
        Previous value: -"Recovery guidance when no studies matched — echoes the constraint and suggests how to broaden. Absent on pages with results."New value: +"Recovery guidance when no studies matched — echoes the constraint and suggests how to broaden, and names nctIds as part of the unmatched criteria when an ID list was supplied. Absent on pages with results, and on an exhausted continuation page, where the cohort already matched and there is nothing to broaden."
      • addedOutput schema / properties / pageExhausted
        Added value: +{
        +  "description": "True when this call supplied a pageToken and the continuation page came back empty — the walk is finished and no further pages exist. Absent on every other response, including an empty first page, which is an unmatched search rather than exhausted pagination.",
        +  "type": "boolean"
        +}
  2. 7 tool updatesv2.9.2
    • Changedclinicaltrials_find_eligible7 fields changed
      • changedInput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedInput schema / additionalProperties
        Added value: +false
      • addedInput schema / properties / location / additionalProperties
        Added value: +false
      • changedOutput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedOutput schema / anyOf
        Added value: +[
        +  {
        +    "not": {
        +      "required": [
        +        "error"
        +      ]
        +    },
        +    "required": [
        +      "studies",
        +      "searchCriteria",
        +      "funnel"
        +    ]
        +  },
        +  {
        +    "required": [
        +      "error"
        +    ]
        +  }
        +]
      • addedOutput schema / properties / error
        Added value: +{
        +  "additionalProperties": {},
        +  "description": "Present when the call failed. Absent on success.",
        +  "properties": {
        +    "code": {
        +      "description": "JSON-RPC error code for this failure.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "data": {
        +      "additionalProperties": {},
        +      "properties": {
        +        "reason": {
        +          "description": "Machine-readable failure mode. Declared by this tool: `blank_value`: A parameter was supplied with a blank, whitespace-only, or empty-list value. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler.",
        +          "examples": [
        +            "blank_value",
        +            "rate_limited"
        +          ],
        +          "type": "string"
        +        },
        +        "recovery": {
        +          "additionalProperties": {},
        +          "description": "Actionable next step for the caller.",
        +          "properties": {
        +            "hint": {
        +              "type": "string"
        +            }
        +          },
        +          "required": [
        +            "hint"
        +          ],
        +          "type": "object"
        +        },
        +        "retryable": {
        +          "description": "Whether retrying may succeed.",
        +          "type": "boolean"
        +        }
        +      },
        +      "type": "object"
        +    },
        +    "message": {
        +      "description": "Human-readable description of what went wrong.",
        +      "type": "string"
        +    }
        +  },
        +  "required": [
        +    "code",
        +    "message"
        +  ],
        +  "type": "object"
        +}
      • removedOutput schema / required
        Removed value: -[
        -  "studies",
        -  "searchCriteria",
        -  "funnel"
        -]
    • Changedclinicaltrials_get_field_definitions6 fields changed
      • changedInput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedInput schema / additionalProperties
        Added value: +false
      • changedOutput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedOutput schema / anyOf
        Added value: +[
        +  {
        +    "not": {
        +      "required": [
        +        "error"
        +      ]
        +    },
        +    "required": [
        +      "fields",
        +      "totalFields"
        +    ]
        +  },
        +  {
        +    "required": [
        +      "error"
        +    ]
        +  }
        +]
      • addedOutput schema / properties / error
        Added value: +{
        +  "additionalProperties": {},
        +  "description": "Present when the call failed. Absent on success.",
        +  "properties": {
        +    "code": {
        +      "description": "JSON-RPC error code for this failure.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "data": {
        +      "additionalProperties": {},
        +      "properties": {
        +        "reason": {
        +          "description": "Machine-readable failure mode. Declared by this tool: `path_not_found`: The dot-notation path does not match any node in the field tree. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler.",
        +          "examples": [
        +            "path_not_found",
        +            "rate_limited"
        +          ],
        +          "type": "string"
        +        },
        +        "recovery": {
        +          "additionalProperties": {},
        +          "description": "Actionable next step for the caller.",
        +          "properties": {
        +            "hint": {
        +              "type": "string"
        +            }
        +          },
        +          "required": [
        +            "hint"
        +          ],
        +          "type": "object"
        +        },
        +        "retryable": {
        +          "description": "Whether retrying may succeed.",
        +          "type": "boolean"
        +        }
        +      },
        +      "type": "object"
        +    },
        +    "message": {
        +      "description": "Human-readable description of what went wrong.",
        +      "type": "string"
        +    }
        +  },
        +  "required": [
        +    "code",
        +    "message"
        +  ],
        +  "type": "object"
        +}
      • removedOutput schema / required
        Removed value: -[
        -  "fields",
        -  "totalFields"
        -]
    • Changedclinicaltrials_get_field_values6 fields changed
      • changedInput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedInput schema / additionalProperties
        Added value: +false
      • changedOutput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedOutput schema / anyOf
        Added value: +[
        +  {
        +    "not": {
        +      "required": [
        +        "error"
        +      ]
        +    },
        +    "required": [
        +      "fieldStats"
        +    ]
        +  },
        +  {
        +    "required": [
        +      "error"
        +    ]
        +  }
        +]
      • addedOutput schema / properties / error
        Added value: +{
        +  "additionalProperties": {},
        +  "description": "Present when the call failed. Absent on success.",
        +  "properties": {
        +    "code": {
        +      "description": "JSON-RPC error code for this failure.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "data": {
        +      "additionalProperties": {},
        +      "properties": {
        +        "reason": {
        +          "description": "Machine-readable failure mode. Declared by this tool: `blank_value`: A parameter was supplied with a blank, whitespace-only, or empty-list value. `field_invalid`: A requested field name is not a valid PascalCase piece name. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler.",
        +          "examples": [
        +            "blank_value",
        +            "field_invalid",
        +            "rate_limited"
        +          ],
        +          "type": "string"
        +        },
        +        "recovery": {
        +          "additionalProperties": {},
        +          "description": "Actionable next step for the caller.",
        +          "properties": {
        +            "hint": {
        +              "type": "string"
        +            }
        +          },
        +          "required": [
        +            "hint"
        +          ],
        +          "type": "object"
        +        },
        +        "retryable": {
        +          "description": "Whether retrying may succeed.",
        +          "type": "boolean"
        +        }
        +      },
        +      "type": "object"
        +    },
        +    "message": {
        +      "description": "Human-readable description of what went wrong.",
        +      "type": "string"
        +    }
        +  },
        +  "required": [
        +    "code",
        +    "message"
        +  ],
        +  "type": "object"
        +}
      • removedOutput schema / required
        Removed value: -[
        -  "fieldStats"
        -]
    • Changedclinicaltrials_get_study_count6 fields changed
      • changedInput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedInput schema / additionalProperties
        Added value: +false
      • changedOutput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedOutput schema / anyOf
        Added value: +[
        +  {
        +    "not": {
        +      "required": [
        +        "error"
        +      ]
        +    },
        +    "required": [
        +      "totalCount"
        +    ]
        +  },
        +  {
        +    "required": [
        +      "error"
        +    ]
        +  }
        +]
      • addedOutput schema / properties / error
        Added value: +{
        +  "additionalProperties": {},
        +  "description": "Present when the call failed. Absent on success.",
        +  "properties": {
        +    "code": {
        +      "description": "JSON-RPC error code for this failure.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "data": {
        +      "additionalProperties": {},
        +      "properties": {
        +        "reason": {
        +          "description": "Machine-readable failure mode. Declared by this tool: `blank_value`: A parameter was supplied with a blank, whitespace-only, or empty-list value. `field_invalid`: A field name in the advanced filter or AREA[] expression is invalid (often a module name instead of a piece name). `enum_invalid`: statusFilter or phaseFilter contains a value ClinicalTrials.gov does not accept. `query_parse_error`: A free-text query or advancedFilter expression uses syntax the upstream Essie parser rejects — typically a `[` or `]` outside an AREA[…] / RANGE[…] expression, an unmatched `(` / `)`, or an unterminated quote in a query/conditionQuery/etc. value. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler.",
        +          "examples": [
        +            "blank_value",
        +            "field_invalid",
        +            "enum_invalid",
        +            "query_parse_error",
        +            "rate_limited"
        +          ],
        +          "type": "string"
        +        },
        +        "recovery": {
        +          "additionalProperties": {},
        +          "description": "Actionable next step for the caller.",
        +          "properties": {
        +            "hint": {
        +              "type": "string"
        +            }
        +          },
        +          "required": [
        +            "hint"
        +          ],
        +          "type": "object"
        +        },
        +        "retryable": {
        +          "description": "Whether retrying may succeed.",
        +          "type": "boolean"
        +        }
        +      },
        +      "type": "object"
        +    },
        +    "message": {
        +      "description": "Human-readable description of what went wrong.",
        +      "type": "string"
        +    }
        +  },
        +  "required": [
        +    "code",
        +    "message"
        +  ],
        +  "type": "object"
        +}
      • removedOutput schema / required
        Removed value: -[
        -  "totalCount"
        -]
    • Changedclinicaltrials_get_study_record7 fields changed
      • changedInput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedInput schema / additionalProperties
        Added value: +false
      • addedInput schema / properties / nearLocation / additionalProperties
        Added value: +false
      • changedOutput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedOutput schema / anyOf
        Added value: +[
        +  {
        +    "not": {
        +      "required": [
        +        "error"
        +      ]
        +    },
        +    "required": [
        +      "study",
        +      "filtersApplied"
        +    ]
        +  },
        +  {
        +    "required": [
        +      "error"
        +    ]
        +  }
        +]
      • addedOutput schema / properties / error
        Added value: +{
        +  "additionalProperties": {},
        +  "description": "Present when the call failed. Absent on success.",
        +  "properties": {
        +    "code": {
        +      "description": "JSON-RPC error code for this failure.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "data": {
        +      "additionalProperties": {},
        +      "properties": {
        +        "reason": {
        +          "description": "Machine-readable failure mode. Declared by this tool: `study_not_found`: The provided NCT ID does not match any study at ClinicalTrials.gov. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler.",
        +          "examples": [
        +            "study_not_found",
        +            "rate_limited"
        +          ],
        +          "type": "string"
        +        },
        +        "recovery": {
        +          "additionalProperties": {},
        +          "description": "Actionable next step for the caller.",
        +          "properties": {
        +            "hint": {
        +              "type": "string"
        +            }
        +          },
        +          "required": [
        +            "hint"
        +          ],
        +          "type": "object"
        +        },
        +        "retryable": {
        +          "description": "Whether retrying may succeed.",
        +          "type": "boolean"
        +        }
        +      },
        +      "type": "object"
        +    },
        +    "message": {
        +      "description": "Human-readable description of what went wrong.",
        +      "type": "string"
        +    }
        +  },
        +  "required": [
        +    "code",
        +    "message"
        +  ],
        +  "type": "object"
        +}
      • removedOutput schema / required
        Removed value: -[
        -  "study",
        -  "filtersApplied"
        -]
    • Changedclinicaltrials_get_study_results6 fields changed
      • changedInput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedInput schema / additionalProperties
        Added value: +false
      • changedOutput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedOutput schema / anyOf
        Added value: +[
        +  {
        +    "not": {
        +      "required": [
        +        "error"
        +      ]
        +    },
        +    "required": [
        +      "results"
        +    ]
        +  },
        +  {
        +    "required": [
        +      "error"
        +    ]
        +  }
        +]
      • addedOutput schema / properties / error
        Added value: +{
        +  "additionalProperties": {},
        +  "description": "Present when the call failed. Absent on success.",
        +  "properties": {
        +    "code": {
        +      "description": "JSON-RPC error code for this failure.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "data": {
        +      "additionalProperties": {},
        +      "properties": {
        +        "reason": {
        +          "description": "Machine-readable failure mode. Declared by this tool: `blank_value`: A parameter was supplied with a blank, whitespace-only, or empty-list value. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler.",
        +          "examples": [
        +            "blank_value",
        +            "rate_limited"
        +          ],
        +          "type": "string"
        +        },
        +        "recovery": {
        +          "additionalProperties": {},
        +          "description": "Actionable next step for the caller.",
        +          "properties": {
        +            "hint": {
        +              "type": "string"
        +            }
        +          },
        +          "required": [
        +            "hint"
        +          ],
        +          "type": "object"
        +        },
        +        "retryable": {
        +          "description": "Whether retrying may succeed.",
        +          "type": "boolean"
        +        }
        +      },
        +      "type": "object"
        +    },
        +    "message": {
        +      "description": "Human-readable description of what went wrong.",
        +      "type": "string"
        +    }
        +  },
        +  "required": [
        +    "code",
        +    "message"
        +  ],
        +  "type": "object"
        +}
      • removedOutput schema / required
        Removed value: -[
        -  "results"
        -]
    • Changedclinicaltrials_search_studies6 fields changed
      • changedInput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedInput schema / additionalProperties
        Added value: +false
      • changedOutput schema / $schema
        Previous value: -"http://json-schema.org/draft-07/schema#"New value: +"https://json-schema.org/draft/2020-12/schema"
      • addedOutput schema / anyOf
        Added value: +[
        +  {
        +    "not": {
        +      "required": [
        +        "error"
        +      ]
        +    },
        +    "required": [
        +      "studies"
        +    ]
        +  },
        +  {
        +    "required": [
        +      "error"
        +    ]
        +  }
        +]
      • addedOutput schema / properties / error
        Added value: +{
        +  "additionalProperties": {},
        +  "description": "Present when the call failed. Absent on success.",
        +  "properties": {
        +    "code": {
        +      "description": "JSON-RPC error code for this failure.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "data": {
        +      "additionalProperties": {},
        +      "properties": {
        +        "reason": {
        +          "description": "Machine-readable failure mode. Declared by this tool: `blank_value`: A parameter was supplied with a blank, whitespace-only, or empty-list value. `ids_not_found`: One or more NCT IDs in the nctIds filter are not present at ClinicalTrials.gov. `field_invalid`: A field name in the fields parameter or AREA[] expression is invalid (often a module name instead of a piece name). `enum_invalid`: statusFilter or phaseFilter contains a value ClinicalTrials.gov does not accept. `query_parse_error`: A free-text query or advancedFilter expression uses syntax the upstream Essie parser rejects — typically a `[` or `]` outside an AREA[…] / RANGE[…] expression, an unmatched `(` / `)`, or an unterminated quote in a query/conditionQuery/etc. value. `geo_invalid`: geoFilter is not a well-formed distance(lat,lon,radius) expression. `sort_invalid`: sort is not FieldName:asc / FieldName:desc, or names more than 2 fields. `rate_limited`: ClinicalTrials.gov returned 429 after retry budget exhausted. Other values are possible when a failure originates below the handler.",
        +          "examples": [
        +            "blank_value",
        +            "ids_not_found",
        +            "field_invalid",
        +            "enum_invalid",
        +            "query_parse_error",
        +            "geo_invalid",
        +            "sort_invalid",
        +            "rate_limited"
        +          ],
        +          "type": "string"
        +        },
        +        "recovery": {
        +          "additionalProperties": {},
        +          "description": "Actionable next step for the caller.",
        +          "properties": {
        +            "hint": {
        +              "type": "string"
        +            }
        +          },
        +          "required": [
        +            "hint"
        +          ],
        +          "type": "object"
        +        },
        +        "retryable": {
        +          "description": "Whether retrying may succeed.",
        +          "type": "boolean"
        +        }
        +      },
        +      "type": "object"
        +    },
        +    "message": {
        +      "description": "Human-readable description of what went wrong.",
        +      "type": "string"
        +    }
        +  },
        +  "required": [
        +    "code",
        +    "message"
        +  ],
        +  "type": "object"
        +}
      • removedOutput schema / required
        Removed value: -[
        -  "studies"
        -]
  3. 6 tool updatesv2.9.1
    • Changedclinicaltrials_find_eligible3 fields changed
      • removedInput schema / properties / conditions / minItems
        Removed value: -1
      • addedInput schema / properties / locationLimit
        Added value: +{
        +  "default": 10,
        +  "description": "Cap on the sites returned per candidate. Each candidate keeps only the sites matching the requested location at the narrowest level that matched (city, else state, else country), capped at this many; the rest of the study's registered sites are omitted. The cap governs those matched sites — when none of them is recruiting, the candidate's nearest recruiting site is added on top of it, so a candidate can carry one site more than this. Raise it to see more nearby sites, or fetch the complete site list with clinicaltrials_get_study_record. Each candidate reports totalLocations / matchedLocations / locationsTruncated / nearestRecruitingSiteAdded in locationSummary only when the bound actually dropped sites.",
        +  "maximum": 500,
        +  "minimum": 1,
        +  "type": "integer"
        +}
      • changedOutput schema / properties / studies / description
        Previous value: -"Matching studies with eligibility and location fields."New value: +"Matching studies with eligibility and location fields. Each candidate's protocolSection.contactsLocationsModule.locations is BOUNDED to the sites matching the requested location (capped at locationLimit) plus, when none of those is recruiting, the candidate's nearest recruiting site — not the study's full registered site list. A candidate whose sites were bounded also carries a top-level locationSummary object — { totalLocations, matchedLocations, locationsTruncated, nearestRecruitingSiteAdded?, retrieveFullStudyWith } — absent when nothing was dropped; nearestRecruitingSiteAdded is present only when that extra site was added. Fetch a study's complete record and site list with clinicaltrials_get_study_record."
    • Changedclinicaltrials_get_field_definitions1 field changed
      • addedOutput schema / properties / totalMatches
        Added value: +{
        +  "description": "Total fields matching the query before the limit cap was applied (search mode only). Compare against `shown` to size a follow-up limit, or to see that a capped result set is barely over the cap rather than hundreds deep.",
        +  "type": "number"
        +}
    • Changedclinicaltrials_get_field_values2 fields changed
      • changedInput schema / properties / fields / anyOf
        Previous value: -[
        -  {
        -    "description": "A single PascalCase field name.",
        -    "type": "string"
        -  },
        -  {
        -    "description": "Multiple PascalCase field names (at least one required).",
        -    "items": {
        -      "type": "string"
        -    },
        -    "minItems": 1,
        -    "type": "array"
        -  }
        -]New value: +[
        +  {
        +    "description": "A single PascalCase field name.",
        +    "type": "string"
        +  },
        +  {
        +    "description": "Multiple PascalCase field names (at least one required).",
        +    "items": {
        +      "type": "string"
        +    },
        +    "type": "array"
        +  }
        +]
      • changedInput schema / properties / fields / description
        Previous value: -"PascalCase field name(s) to get value statistics for. Examples: OverallStatus, Phase, StudyType, Sex, LeadSponsorClass. Use clinicaltrials_get_field_definitions with a query to find more field names."New value: +"PascalCase field name(s) to get value statistics for — an empty list is rejected, not treated as \"every field\". Examples: OverallStatus, Phase, StudyType, Sex, LeadSponsorClass. Use clinicaltrials_get_field_definitions with a query to find more field names."
    • Changedclinicaltrials_get_study_count9 fields changed
      • changedInput schema / properties / conditionQuery / description
        Previous value: -"Condition/disease-specific search. E.g., \"Type 2 Diabetes\", \"non-small cell lung cancer\". Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Condition/disease-specific search. E.g., \"Type 2 Diabetes\", \"non-small cell lung cancer\". Matches Condition, BriefTitle, OfficialTitle, ConditionMeshTerm, ConditionAncestorTerm, Keyword, and NCTId. ConditionAncestorTerm is the MeSH umbrella above the conditions a study itself lists, so results run broader than those lists — a study can match a parent term it never names. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / interventionQuery / description
        Previous value: -"Intervention/treatment search. E.g., \"pembrolizumab\", \"cognitive behavioral therapy\". Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Intervention/treatment search. E.g., \"pembrolizumab\", \"cognitive behavioral therapy\". Matches InterventionName, InterventionType, ArmGroupType, InterventionOtherName, BriefTitle, OfficialTitle, ArmGroupLabel, InterventionMeshTerm, Keyword, InterventionAncestorTerm, InterventionDescription, and ArmGroupDescription. InterventionAncestorTerm is the MeSH umbrella above the interventions a study itself lists, so results run broader than those lists. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / locationQuery / description
        Previous value: -"Location search — city, state, country, or facility name. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Location search — city, state, country, or facility name. Matches LocationCity, LocationState, LocationCountry, LocationFacility, and LocationZip; a study matches when any of its sites does. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / outcomeQuery / description
        Previous value: -"Search within outcome measure fields. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Search within outcome measure fields. Matches PrimaryOutcomeMeasure, SecondaryOutcomeMeasure, OtherOutcomeMeasure, and OutcomeMeasureTitle, plus their description counterparts PrimaryOutcomeDescription, SecondaryOutcomeDescription, OtherOutcomeDescription, OutcomeMeasureDescription, and OutcomeMeasurePopulationDescription — so a term appearing only in outcome prose still matches. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / phaseFilter / description
        Previous value: -"Filter by trial phase. Values: EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA."New value: +"Filter by trial phase. Omit to count all phases — an empty list is rejected, not treated as \"no filter\". Values: EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA."
      • changedInput schema / properties / query / description
        Previous value: -"General free-text search across all fields. Plain words plus AND, OR, NOT. `[ ]` are reserved (advancedFilter AREA[] only); `( )` group sub-expressions and work when matched; `,` acts as AND. For field-scoped searches, use the dedicated *Query parameters (conditionQuery, interventionQuery, etc.) or advancedFilter with AREA[FieldName]value."New value: +"General free-text search across all fields. Runs the 57-field relevance search ClinicalTrials.gov publishes for this parameter — NCTId, NCTIdAlias, OrgStudyId, SecondaryId, Acronym, BriefTitle, OfficialTitle, Condition, InterventionName, InterventionOtherName, Phase, StdAge, StudyType, BriefSummary, outcome measures and their descriptions, LeadSponsorName, CollaboratorName, the Location* fields, the Design* fields, and the ConditionAncestorTerm/InterventionAncestorTerm MeSH umbrellas — so a hit need not carry your term in the field you had in mind. Plain words plus AND, OR, NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression — those work here as well as in advancedFilter, so AREA[Phase]PHASE2 is accepted in this parameter; a stray bracket fails. `( )` group sub-expressions and work when matched; `,` acts as AND. The dedicated *Query parameters (conditionQuery, interventionQuery, etc.) scope a search to one field."
      • changedInput schema / properties / sponsorQuery / description
        Previous value: -"Sponsor/collaborator name search. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Sponsor/collaborator name search. Matches LeadSponsorName, CollaboratorName, and OrgFullName. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / statusFilter / description
        Previous value: -"Filter by study status. Values: RECRUITING, COMPLETED, ACTIVE_NOT_RECRUITING, NOT_YET_RECRUITING, ENROLLING_BY_INVITATION, SUSPENDED, TERMINATED, WITHDRAWN, UNKNOWN, WITHHELD, NO_LONGER_AVAILABLE, AVAILABLE, APPROVED_FOR_MARKETING, TEMPORARILY_NOT_AVAILABLE."New value: +"Filter by study status. Omit to count all statuses — an empty list is rejected, not treated as \"no filter\". Values: RECRUITING, COMPLETED, ACTIVE_NOT_RECRUITING, NOT_YET_RECRUITING, ENROLLING_BY_INVITATION, SUSPENDED, TERMINATED, WITHDRAWN, UNKNOWN, WITHHELD, NO_LONGER_AVAILABLE, AVAILABLE, APPROVED_FOR_MARKETING, TEMPORARILY_NOT_AVAILABLE."
      • changedInput schema / properties / titleQuery / description
        Previous value: -"Search within study titles and acronyms only. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Search within study titles and acronyms only. Matches Acronym, BriefTitle, and OfficialTitle. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
    • Changedclinicaltrials_get_study_results8 fields changed
      • addedInput schema / properties / adverseEventLimit
        Added value: +{
        +  "description": "Optional cap on the number of serious and other adverse events returned per study, applied to each list separately in upstream order. Omit for no cap (every event). Applies to full mode only — summary mode already ranks the top 20 by participants affected. Event groups are never capped. Upstream totals preserved in filtersApplied.totalSeriousEvents / totalOtherEvents only when the cap trims a list.",
        +  "maximum": 500,
        +  "minimum": 1,
        +  "type": "integer"
        +}
      • changedInput schema / properties / nctIds / anyOf
        Previous value: -[
        -  {
        -    "description": "A single NCT ID.",
        -    "pattern": "^NCT\\d{8}$",
        -    "type": "string"
        -  },
        -  {
        -    "description": "Multiple NCT IDs (max 20).",
        -    "items": {
        -      "pattern": "^NCT\\d{8}$",
        -      "type": "string"
        -    },
        -    "maxItems": 20,
        -    "minItems": 1,
        -    "type": "array"
        -  }
        -]New value: +[
        +  {
        +    "description": "A single NCT ID.",
        +    "pattern": "^NCT\\d{8}$",
        +    "type": "string"
        +  },
        +  {
        +    "description": "Multiple NCT IDs (max 20).",
        +    "items": {
        +      "pattern": "^NCT\\d{8}$",
        +      "type": "string"
        +    },
        +    "maxItems": 20,
        +    "type": "array"
        +  }
        +]
      • changedInput schema / properties / nctIds / description
        Previous value: -"One or more NCT IDs (max 20). E.g., \"NCT12345678\" or [\"NCT12345678\", \"NCT87654321\"]. Use summary=true for large batches to avoid large payloads."New value: +"One or more NCT IDs (max 20) — an empty list is rejected. E.g., \"NCT12345678\" or [\"NCT12345678\", \"NCT87654321\"]. Use summary=true for large batches to avoid large payloads."
      • addedInput schema / properties / outcomeLimit
        Added value: +{
        +  "description": "Optional cap on the number of outcome measures returned per study, taken in the order ClinicalTrials.gov publishes them. Omit for no cap (every measure). Applies to full mode only — summary mode is already condensed. Each surviving measure keeps its complete groups/classes/measurements/analyses tree. Upstream total preserved in filtersApplied.totalOutcomes only when the cap trims the list.",
        +  "maximum": 100,
        +  "minimum": 1,
        +  "type": "integer"
        +}
      • changedInput schema / properties / sections / description
        Previous value: -"Filter which sections to return. Values: outcomes, adverseEvents, participantFlow, baseline, moreInfo. Omit for all sections."New value: +"Filter which sections to return. Values: outcomes, adverseEvents, participantFlow, baseline, moreInfo. Omit for all sections — an empty list is rejected, not treated as omission."
      • changedInput schema / properties / summary / description
        Previous value: -"Return condensed summaries instead of full data. Reduces payload from ~200KB to ~5KB per study. Summaries include outcome titles, types, timeframes, group counts, and top-level stats — omitting individual measurements, analyses, and per-group data."New value: +"Return condensed summaries instead of full data. Full mode renders every row and field on both output channels, so a large results set can exceed 500KB per study; summary mode reduces that to ~5KB. Summaries include outcome titles, types, timeframes, group counts, and top-level stats — omitting individual measurements, analyses, and per-group data. For a middle ground, keep full mode and cap the two lists that carry the bulk with outcomeLimit / adverseEventLimit."
      • addedOutput schema / properties / results / items / properties / filtersApplied
        Added value: +{
        +  "additionalProperties": false,
        +  "description": "What a cap trimmed on this study — present only when a cap actually reduced a list. Absent means the payload is the complete upstream set for the requested sections.",
        +  "properties": {
        +    "adverseEventLimit": {
        +      "description": "Echo of the adverseEventLimit input — present only when the cap trimmed a list.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "outcomeLimit": {
        +      "description": "Echo of the outcomeLimit input — present only when the cap trimmed the list.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "totalOtherEvents": {
        +      "description": "Upstream other adverse event count before adverseEventLimit trimmed the list.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "totalOutcomes": {
        +      "description": "Upstream outcome measure count before outcomeLimit trimmed the list.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "totalSeriousEvents": {
        +      "description": "Upstream serious adverse event count before adverseEventLimit trimmed the list.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    }
        +  },
        +  "type": "object"
        +}
      • addedOutput schema / properties / truncated
        Added value: +{
        +  "description": "True when a cap trimmed a list on at least one study; absent when nothing was trimmed, matching filtersApplied one level down. Which study and which list is named in that study’s filtersApplied.",
        +  "type": "boolean"
        +}
    • Changedclinicaltrials_search_studies13 fields changed
      • changedInput schema / properties / conditionQuery / description
        Previous value: -"Condition/disease-specific search. E.g., \"Type 2 Diabetes\", \"non-small cell lung cancer\". Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Condition/disease-specific search. E.g., \"Type 2 Diabetes\", \"non-small cell lung cancer\". Matches Condition, BriefTitle, OfficialTitle, ConditionMeshTerm, ConditionAncestorTerm, Keyword, and NCTId. ConditionAncestorTerm is the MeSH umbrella above the conditions a study itself lists, so results run broader than those lists — a study can match a parent term it never names. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / fields / description
        Previous value: -"PascalCase leaf names to return; strongly recommended since full records are ~70KB. Common leaves: NCTId, BriefTitle, BriefSummary, OverallStatus, Phase, LeadSponsorName, Condition. Call clinicaltrials_get_field_definitions with a concept query (e.g., \"adverse events\", \"eligibility\") to find the exact leaf for any concept."New value: +"PascalCase leaf names to return; strongly recommended since full records are ~70KB. Omit for the compact index projection — an empty list is rejected, not treated as omission. Common leaves: NCTId, BriefTitle, BriefSummary, OverallStatus, Phase, LeadSponsorName, Condition. Call clinicaltrials_get_field_definitions with a concept query (e.g., \"adverse events\", \"eligibility\") to find the exact leaf for any concept."
      • changedInput schema / properties / geoFilter / description
        Previous value: -"Geographic proximity filter. Format: distance(lat,lon,radius). E.g., \"distance(47.6062,-122.3321,50mi)\" for studies within 50 miles of Seattle. When set, each study's locations are re-sorted by proximity to the center so the nearest matched site leads, annotated with its distance in miles; the full location list is preserved."New value: +"Geographic proximity filter. Format: distance(lat,lon,radius), where radius carries a `mi` or `km` suffix — e.g. \"distance(47.6062,-122.3321,50mi)\" for studies within 50 miles of Seattle. Always include the suffix: a bare radius is accepted upstream but interpreted as meters, which silently matches almost nothing. When set, each study's locations are re-sorted by proximity to the center so the nearest matched site leads, annotated with its distance in miles; the full location list is preserved."
      • changedInput schema / properties / interventionQuery / description
        Previous value: -"Intervention/treatment search. E.g., \"pembrolizumab\", \"cognitive behavioral therapy\". Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Intervention/treatment search. E.g., \"pembrolizumab\", \"cognitive behavioral therapy\". Matches InterventionName, InterventionType, ArmGroupType, InterventionOtherName, BriefTitle, OfficialTitle, ArmGroupLabel, InterventionMeshTerm, Keyword, InterventionAncestorTerm, InterventionDescription, and ArmGroupDescription. InterventionAncestorTerm is the MeSH umbrella above the interventions a study itself lists, so results run broader than those lists. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / locationQuery / description
        Previous value: -"Location search — city, state, country, or facility name. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Location search — city, state, country, or facility name. Matches LocationCity, LocationState, LocationCountry, LocationFacility, and LocationZip; a study matches when any of its sites does. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / nctIds / description
        Previous value: -"Filter to specific NCT IDs for batch lookups."New value: +"Filter to specific NCT IDs for batch lookups. Omit to search every study — an empty list is rejected, not treated as \"no filter\". Supplying this lifts the default unknown-enrollment exclusion, so an ID you name is never filtered out of its own lookup."
      • changedInput schema / properties / outcomeQuery / description
        Previous value: -"Search within outcome measure fields. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Search within outcome measure fields. Matches PrimaryOutcomeMeasure, SecondaryOutcomeMeasure, OtherOutcomeMeasure, and OutcomeMeasureTitle, plus their description counterparts PrimaryOutcomeDescription, SecondaryOutcomeDescription, OtherOutcomeDescription, OutcomeMeasureDescription, and OutcomeMeasurePopulationDescription — so a term appearing only in outcome prose still matches. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / phaseFilter / description
        Previous value: -"Filter by trial phase. Values: EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA."New value: +"Filter by trial phase. Omit to search all phases — an empty list is rejected, not treated as \"no filter\". Values: EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA."
      • changedInput schema / properties / query / description
        Previous value: -"General free-text search across all fields. Plain words plus AND, OR, NOT. `[ ]` are reserved (advancedFilter AREA[] only); `( )` group sub-expressions and work when matched; `,` acts as AND. For field-scoped searches, use the dedicated *Query parameters (conditionQuery, interventionQuery, etc.) or advancedFilter with AREA[FieldName]value."New value: +"General free-text search across all fields. Runs the 57-field relevance search ClinicalTrials.gov publishes for this parameter — NCTId, NCTIdAlias, OrgStudyId, SecondaryId, Acronym, BriefTitle, OfficialTitle, Condition, InterventionName, InterventionOtherName, Phase, StdAge, StudyType, BriefSummary, outcome measures and their descriptions, LeadSponsorName, CollaboratorName, the Location* fields, the Design* fields, and the ConditionAncestorTerm/InterventionAncestorTerm MeSH umbrellas — so a hit need not carry your term in the field you had in mind. Plain words plus AND, OR, NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression — those work here as well as in advancedFilter, so AREA[Phase]PHASE2 is accepted in this parameter; a stray bracket fails. `( )` group sub-expressions and work when matched; `,` acts as AND. The dedicated *Query parameters (conditionQuery, interventionQuery, etc.) scope a search to one field."
      • changedInput schema / properties / sponsorQuery / description
        Previous value: -"Sponsor/collaborator name search. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Sponsor/collaborator name search. Matches LeadSponsorName, CollaboratorName, and OrgFullName. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / statusFilter / description
        Previous value: -"Filter by study status. Values: RECRUITING, COMPLETED, ACTIVE_NOT_RECRUITING, NOT_YET_RECRUITING, ENROLLING_BY_INVITATION, SUSPENDED, TERMINATED, WITHDRAWN, UNKNOWN, WITHHELD, NO_LONGER_AVAILABLE, AVAILABLE, APPROVED_FOR_MARKETING, TEMPORARILY_NOT_AVAILABLE."New value: +"Filter by study status. Omit to search all statuses — an empty list is rejected, not treated as \"no filter\". Values: RECRUITING, COMPLETED, ACTIVE_NOT_RECRUITING, NOT_YET_RECRUITING, ENROLLING_BY_INVITATION, SUSPENDED, TERMINATED, WITHDRAWN, UNKNOWN, WITHHELD, NO_LONGER_AVAILABLE, AVAILABLE, APPROVED_FOR_MARKETING, TEMPORARILY_NOT_AVAILABLE."
      • changedInput schema / properties / titleQuery / description
        Previous value: -"Search within study titles and acronyms only. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Search within study titles and acronyms only. Matches Acronym, BriefTitle, and OfficialTitle. Plain words plus AND/OR/NOT. `[ ]` are valid only inside an AREA[FieldName]value or RANGE[min, max] expression, which this parameter accepts; a stray bracket fails. `( )` group sub-expressions when matched; `,` acts as AND."
      • changedOutput schema / properties / nextPageToken / description
        Previous value: -"Token for the next page. Absent on last page."New value: +"Token for the next page. Absent when this response already carries every matching study; otherwise it mirrors the upstream cursor, which ClinicalTrials.gov emits whenever a page fills to pageSize — so on a continuation page a token can still lead to an empty page."
  4. 1 tool updatev2.8.2
    • Changedclinicaltrials_find_eligible5 fields changed
      • changedOutput schema / properties / searchCriteria / description
        Previous value: -"Normalized search criteria applied to this eligibility query."New value: +"Normalized search criteria applied to this eligibility query, including the exact upstream query strings needed to reproduce the full match set via clinicaltrials_search_studies (replay with includeUnknownEnrollment=true, which find_eligible always sets)."
      • addedOutput schema / properties / searchCriteria / properties / advancedFilter
        Added value: +{
        +  "description": "The exact AREA[] advancedFilter (age range, plus sex/healthy-volunteer when constrained) sent upstream. Pass as advancedFilter to clinicaltrials_search_studies to reproduce the demographic constraints.",
        +  "type": "string"
        +}
      • addedOutput schema / properties / searchCriteria / properties / conditionQuery
        Added value: +{
        +  "description": "The exact queryCond string sent upstream (multi-word terms quoted, OR-joined). Pass as conditionQuery to clinicaltrials_search_studies to reproduce the full match set beyond the maxResults cap.",
        +  "type": "string"
        +}
      • changedOutput schema / properties / searchCriteria / properties / location / description
        Previous value: -"Location searched."New value: +"The exact queryLocn string sent upstream (city/state/country joined). Pass as locationQuery to clinicaltrials_search_studies to reproduce the location filter beyond the maxResults cap."
      • addedOutput schema / properties / searchCriteria / properties / statusFilter
        Added value: +{
        +  "description": "The status filter applied ([\"RECRUITING\"] when recruitingOnly). Pass as statusFilter to clinicaltrials_search_studies. Absent when recruitingOnly is false.",
        +  "items": {
        +    "type": "string"
        +  },
        +  "type": "array"
        +}
  5. 1 tool updatev2.8.0
    • Changedclinicaltrials_search_studies2 fields changed
      • changedOutput schema / properties / requestedFields / description
        Previous value: -"Echo of the explicit fields parameter — present only when the caller passed fields. Lifts the default truncation cap so all requested leaves render in full."New value: +"Echo of the explicit fields parameter — present only when the caller passed fields. Signals that studies carry the requested leaves at full fidelity (not the default compact index) and that the rendered truncation cap is lifted so all of them appear."
      • changedOutput schema / properties / studies / description
        Previous value: -"Matching studies. Each entry is a nested ClinicalTrials.gov study record — top-level keys: protocolSection, derivedSection, hasResults, resultsSection, documentSection. Use clinicaltrials_get_field_definitions to explore the schema."New value: +"Matching studies. By default each entry is a COMPACT index projection — nctId, briefTitle, overallStatus, phases, enrollmentCount, leadSponsor, conditions, and a bounded locations summary ({ total, nearest }) — mirroring the rendered result, NOT the full ~70KB record. Pass the fields parameter to receive exactly the requested leaves at full fidelity instead (e.g. all locations). Fetch a full single record with clinicaltrials_get_study_record."
  6. 4 tool updatesv2.7.1
    • Changedclinicaltrials_get_field_values3 fields changed
      • changedInput schema / properties / fields / anyOf
        Previous value: -[
        -  {
        -    "description": "A single PascalCase field name.",
        -    "type": "string"
        -  },
        -  {
        -    "description": "Multiple PascalCase field names.",
        -    "items": {
        -      "type": "string"
        -    },
        -    "type": "array"
        -  }
        -]New value: +[
        +  {
        +    "description": "A single PascalCase field name.",
        +    "type": "string"
        +  },
        +  {
        +    "description": "Multiple PascalCase field names (at least one required).",
        +    "items": {
        +      "type": "string"
        +    },
        +    "minItems": 1,
        +    "type": "array"
        +  }
        +]
      • addedOutput schema / properties / fieldStats / items / properties / multiValued
        Added value: +{
        +  "description": "True when the field is array-typed (a study can carry several values, e.g. Phase, Condition), so the per-value studiesCount buckets sum above the study total. Use to avoid computing a percentage against the corpus.",
        +  "type": "boolean"
        +}
      • changedOutput schema / properties / fieldStats / items / properties / topValues / description
        Previous value: -"Values ranked by frequency (capped at 250 by the API). Present for ENUM/STRING fields."New value: +"Values ranked by frequency (capped at 250 by the API). Present for ENUM/STRING fields. When multiValued is true, studiesCount sums can exceed the study total."
    • Changedclinicaltrials_get_study_count1 field changed
      • changedOutput schema / properties / searchCriteria / description
        Previous value: -"Echo of active query/filter criteria applied to this count."New value: +"Echo of active query/filter criteria applied to this count, including sentinelFilterActive when the default unknown-enrollment exclusion is in effect."
    • Changedclinicaltrials_get_study_record7 fields changed
      • changedInput schema / properties / locationLimit / description
        Previous value: -"Optional cap on the number of locations returned. Omit for no cap (full upstream list). Pairs naturally with nearLocation for narrowing a large multi-site trial. Original total preserved in filtersApplied.totalLocations whenever a cap is applied."New value: +"Optional cap on the number of locations returned. Omit for no cap (full upstream list). Pairs naturally with nearLocation for narrowing a large multi-site trial. Original total preserved in filtersApplied.totalLocations only when the cap trims the list."
      • changedInput schema / properties / nearLocation / description
        Previous value: -"Filter returned locations to those within radius of (lat, lon) and sort by distance. Adds distanceMi to each location. Locations without published coordinates are dropped — most US sites carry them; international sites less reliably so. For broader geographic filtering across studies, use clinicaltrials_search_studies with geoFilter."New value: +"Filter returned locations to those within radius of (lat, lon) and sort by distance. Adds distanceMi to each location. Locations without published coordinates are dropped — most US sites carry them; international sites less reliably so. Distances reflect ClinicalTrials.gov geocoding granularity — typically city-centroid, not facility-level — so multiple sites in the same city resolve to near-identical distances. For broader geographic filtering across studies, use clinicaltrials_search_studies with geoFilter."
      • changedInput schema / properties / outcomeLimit / description
        Previous value: -"Optional cap on the number of secondary and other outcomes returned. Omit for no cap (full upstream lists). Primary outcomes are never capped. Original totals preserved in filtersApplied.totalSecondaryOutcomes / totalOtherOutcomes whenever a cap is applied."New value: +"Optional cap on the number of secondary and other outcomes returned. Omit for no cap (full upstream lists). Primary outcomes are never capped. Original totals preserved in filtersApplied.totalSecondaryOutcomes / totalOtherOutcomes only when the cap trims a list."
      • changedInput schema / properties / referenceLimit / description
        Previous value: -"Optional cap on the number of references returned. Omit for no cap (full upstream list). Original total preserved in filtersApplied.totalReferences whenever a cap is applied. seeAlsoLinks are never capped."New value: +"Optional cap on the number of references returned. Omit for no cap (full upstream list). Original total preserved in filtersApplied.totalReferences only when the cap trims the list. seeAlsoLinks are never capped."
      • changedOutput schema / properties / filtersApplied / properties / locationLimit / description
        Previous value: -"Echo of the locationLimit input."New value: +"Echo of the locationLimit input — present only when the cap trimmed the list."
      • changedOutput schema / properties / filtersApplied / properties / outcomeLimit / description
        Previous value: -"Echo of the outcomeLimit input."New value: +"Echo of the outcomeLimit input — present only when the cap trimmed a list."
      • changedOutput schema / properties / filtersApplied / properties / referenceLimit / description
        Previous value: -"Echo of the referenceLimit input."New value: +"Echo of the referenceLimit input — present only when the cap trimmed the list."
    • Changedclinicaltrials_search_studies1 field changed
      • changedInput schema / properties / geoFilter / description
        Previous value: -"Geographic proximity filter. Format: distance(lat,lon,radius). E.g., \"distance(47.6062,-122.3321,50mi)\" for studies within 50 miles of Seattle."New value: +"Geographic proximity filter. Format: distance(lat,lon,radius). E.g., \"distance(47.6062,-122.3321,50mi)\" for studies within 50 miles of Seattle. When set, each study's locations are re-sorted by proximity to the center so the nearest matched site leads, annotated with its distance in miles; the full location list is preserved."
  7. 4 tool updatesv2.7.0
    • Changedclinicaltrials_find_eligible1 field changed
      • changedInput schema / properties / conditions / description
        Previous value: -"Medical conditions or diagnoses. E.g., [\"Type 2 Diabetes\", \"Hypertension\"]. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."New value: +"Medical conditions or diagnoses, e.g. [\"Type 2 Diabetes\", \"Hypertension\"]. Each entry is matched as a condition (multi-word entries match as a phrase); multiple entries are combined with OR, so studies for any listed condition qualify. Returned studies are re-ranked so those whose own condition list names a requested condition rank above tangential matches the upstream fuzzy search pulls in via the MeSH umbrella."
    • Changedclinicaltrials_get_field_definitions4 fields changed
      • addedOutput schema / properties / cap
        Added value: +{
        +  "description": "The limit cap applied to this search (search mode only).",
        +  "type": "number"
        +}
      • changedOutput schema / properties / notice / description
        Previous value: -"Recovery guidance when search mode returns no matches — suggests alternative keywords."New value: +"Recovery guidance when search mode returns no matches, or a truncation note when results are capped."
      • addedOutput schema / properties / shown
        Added value: +{
        +  "description": "Number of fields returned (search mode only).",
        +  "type": "number"
        +}
      • addedOutput schema / properties / truncated
        Added value: +{
        +  "description": "True when the field list was capped by the limit parameter (search mode only).",
        +  "type": "boolean"
        +}
    • Changedclinicaltrials_get_study_record3 fields changed
      • addedInput schema / properties / referenceLimit
        Added value: +{
        +  "description": "Optional cap on the number of references returned. Omit for no cap (full upstream list). Original total preserved in filtersApplied.totalReferences whenever a cap is applied. seeAlsoLinks are never capped.",
        +  "maximum": 100,
        +  "minimum": 1,
        +  "type": "integer"
        +}
      • addedOutput schema / properties / filtersApplied / properties / referenceLimit
        Added value: +{
        +  "description": "Echo of the referenceLimit input.",
        +  "maximum": 9007199254740991,
        +  "minimum": -9007199254740991,
        +  "type": "integer"
        +}
      • addedOutput schema / properties / filtersApplied / properties / totalReferences
        Added value: +{
        +  "description": "Upstream reference count before referenceLimit was applied.",
        +  "maximum": 9007199254740991,
        +  "minimum": -9007199254740991,
        +  "type": "integer"
        +}
    • Changedclinicaltrials_search_studies1 field changed
      • changedInput schema / properties / sort / description
        Previous value: -"Sort order. Format: FieldName:asc or FieldName:desc. E.g., \"LastUpdatePostDate:desc\", \"EnrollmentCount:desc\". Max 2 fields comma-separated. Use clinicaltrials_get_field_definitions to find sortable field names."New value: +"Sort order. Format: FieldName:asc or FieldName:desc. E.g., \"LastUpdatePostDate:desc\", \"EnrollmentCount:desc\". Max 2 fields comma-separated. For \"largest trials\" queries, pair EnrollmentCount:desc with advancedFilter \"AREA[StudyType]INTERVENTIONAL\" — the top enrollment counts are observational registry/claims studies enrolling tens of millions. Enrollment counts are sponsor-reported and not validated upstream beyond the unknown-enrollment sentinel exclusion. Use clinicaltrials_get_field_definitions to find sortable field names."
  8. 3 tool updatesv2.6.5
    • Changedclinicaltrials_find_eligible1 field changed
      • changedInput schema / properties / conditions / description
        Previous value: -"Medical conditions or diagnoses. E.g., [\"Type 2 Diabetes\", \"Hypertension\"]. Plain words only — reserved chars `[ ] ( ) ,` inside an entry will fail."New value: +"Medical conditions or diagnoses. E.g., [\"Type 2 Diabetes\", \"Hypertension\"]. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
    • Changedclinicaltrials_get_study_count7 fields changed
      • changedInput schema / properties / conditionQuery / description
        Previous value: -"Condition/disease-specific search. E.g., \"Type 2 Diabetes\", \"non-small cell lung cancer\". Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Condition/disease-specific search. E.g., \"Type 2 Diabetes\", \"non-small cell lung cancer\". Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / interventionQuery / description
        Previous value: -"Intervention/treatment search. E.g., \"pembrolizumab\", \"cognitive behavioral therapy\". Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Intervention/treatment search. E.g., \"pembrolizumab\", \"cognitive behavioral therapy\". Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / locationQuery / description
        Previous value: -"Location search — city, state, country, or facility name. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Location search — city, state, country, or facility name. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / outcomeQuery / description
        Previous value: -"Search within outcome measure fields. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Search within outcome measure fields. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / query / description
        Previous value: -"General free-text search across all fields. Plain words plus AND, OR, NOT only — reserved chars `[ ] ( ) ,` will fail. For field-scoped searches, use the dedicated *Query parameters (conditionQuery, interventionQuery, etc.) or advancedFilter with AREA[FieldName]value."New value: +"General free-text search across all fields. Plain words plus AND, OR, NOT. `[ ]` are reserved (advancedFilter AREA[] only); `( )` group sub-expressions and work when matched; `,` acts as AND. For field-scoped searches, use the dedicated *Query parameters (conditionQuery, interventionQuery, etc.) or advancedFilter with AREA[FieldName]value."
      • changedInput schema / properties / sponsorQuery / description
        Previous value: -"Sponsor/collaborator name search. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Sponsor/collaborator name search. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / titleQuery / description
        Previous value: -"Search within study titles and acronyms only. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Search within study titles and acronyms only. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
    • Changedclinicaltrials_search_studies7 fields changed
      • changedInput schema / properties / conditionQuery / description
        Previous value: -"Condition/disease-specific search. E.g., \"Type 2 Diabetes\", \"non-small cell lung cancer\". Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Condition/disease-specific search. E.g., \"Type 2 Diabetes\", \"non-small cell lung cancer\". Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / interventionQuery / description
        Previous value: -"Intervention/treatment search. E.g., \"pembrolizumab\", \"cognitive behavioral therapy\". Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Intervention/treatment search. E.g., \"pembrolizumab\", \"cognitive behavioral therapy\". Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / locationQuery / description
        Previous value: -"Location search — city, state, country, or facility name. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Location search — city, state, country, or facility name. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / outcomeQuery / description
        Previous value: -"Search within outcome measure fields. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Search within outcome measure fields. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / query / description
        Previous value: -"General free-text search across all fields. Plain words plus AND, OR, NOT only — reserved chars `[ ] ( ) ,` will fail. For field-scoped searches, use the dedicated *Query parameters (conditionQuery, interventionQuery, etc.) or advancedFilter with AREA[FieldName]value."New value: +"General free-text search across all fields. Plain words plus AND, OR, NOT. `[ ]` are reserved (advancedFilter AREA[] only); `( )` group sub-expressions and work when matched; `,` acts as AND. For field-scoped searches, use the dedicated *Query parameters (conditionQuery, interventionQuery, etc.) or advancedFilter with AREA[FieldName]value."
      • changedInput schema / properties / sponsorQuery / description
        Previous value: -"Sponsor/collaborator name search. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Sponsor/collaborator name search. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
      • changedInput schema / properties / titleQuery / description
        Previous value: -"Search within study titles and acronyms only. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,"New value: +"Search within study titles and acronyms only. Plain words plus AND/OR/NOT. `[ ]` are reserved; `( )` group sub-expressions when matched; `,` acts as AND."
  9. 4 tool updatesv2.6.1
    • Changedclinicaltrials_get_study_count3 fields changed
      • addedInput schema / properties / locationQuery
        Added value: +{
        +  "description": "Location search — city, state, country, or facility name. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,",
        +  "type": "string"
        +}
      • addedInput schema / properties / outcomeQuery
        Added value: +{
        +  "description": "Search within outcome measure fields. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,",
        +  "type": "string"
        +}
      • addedInput schema / properties / titleQuery
        Added value: +{
        +  "description": "Search within study titles and acronyms only. Plain words plus AND/OR/NOT only — reserved chars: [ ] ( ) ,",
        +  "type": "string"
        +}
    • Changedclinicaltrials_get_study_record2 fields changed
      • addedOutput schema / properties / resultsSummary
        Added value: +{
        +  "additionalProperties": false,
        +  "description": "Compact counts of posted results, present when hasResults is true. The full resultsSection is intentionally omitted from this record-level tool — fetch it via clinicaltrials_get_study_results or the clinicaltrials://{nctId} resource.",
        +  "properties": {
        +    "baselineMeasures": {
        +      "description": "Baseline characteristic measures.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "otherAdverseEvents": {
        +      "description": "Distinct other (non-serious) adverse-event terms.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "outcomeMeasures": {
        +      "description": "Posted outcome measures.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "participantFlowPeriods": {
        +      "description": "Participant-flow periods.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    },
        +    "seriousAdverseEvents": {
        +      "description": "Distinct serious adverse-event terms.",
        +      "maximum": 9007199254740991,
        +      "minimum": -9007199254740991,
        +      "type": "integer"
        +    }
        +  },
        +  "type": "object"
        +}
      • changedOutput schema / properties / study / description
        Previous value: -"Full study record with caller-requested filters already applied to locations and outcomes. Top-level keys: protocolSection (identification, status, sponsor, conditions, design, arms/interventions, outcomes, eligibility, contacts/locations), derivedSection (MeSH-normalized terms), hasResults, resultsSection, documentSection. Use clinicaltrials_get_field_definitions to explore the schema."New value: +"Full study record with caller-requested filters already applied to locations and outcomes. Top-level keys: protocolSection (identification, status, sponsor, conditions, design, arms/interventions, outcomes, eligibility, contacts/locations), derivedSection (MeSH-normalized terms), hasResults, documentSection. The heavy resultsSection is omitted — see resultsSummary for counts and clinicaltrials_get_study_results for full results data. Use clinicaltrials_get_field_definitions to explore the schema."
    • Changedclinicaltrials_get_study_results4 fields changed
      • changedInput schema / properties / sections / anyOf
        Previous value: -[
        -  {
        -    "description": "A single section name.",
        -    "enum": [
        -      "outcomes",
        -      "adverseEvents",
        -      "participantFlow",
        -      "baseline"
        -    ],
        -    "type": "string"
        -  },
        -  {
        -    "description": "Multiple section names.",
        -    "items": {
        -      "enum": [
        -        "outcomes",
        -        "adverseEvents",
        -        "participantFlow",
        -        "baseline"
        -      ],
        -      "type": "string"
        -    },
        -    "type": "array"
        -  }
        -]New value: +[
        +  {
        +    "description": "A single section name.",
        +    "enum": [
        +      "outcomes",
        +      "adverseEvents",
        +      "participantFlow",
        +      "baseline",
        +      "moreInfo"
        +    ],
        +    "type": "string"
        +  },
        +  {
        +    "description": "Multiple section names.",
        +    "items": {
        +      "enum": [
        +        "outcomes",
        +        "adverseEvents",
        +        "participantFlow",
        +        "baseline",
        +        "moreInfo"
        +      ],
        +      "type": "string"
        +    },
        +    "type": "array"
        +  }
        +]
      • changedInput schema / properties / sections / description
        Previous value: -"Filter which sections to return. Values: outcomes, adverseEvents, participantFlow, baseline. Omit for all sections."New value: +"Filter which sections to return. Values: outcomes, adverseEvents, participantFlow, baseline, moreInfo. Omit for all sections."
      • changedOutput schema / properties / results / items / properties / adverseEvents / description
        Previous value: -"Adverse events. Summary mode: timeFrame, groupCount, seriousEventCount, otherEventCount. Full mode: adds eventGroups, seriousEvents, otherEvents with per-event term and per-group affected/at-risk stats."New value: +"Adverse events. Summary mode: timeFrame, groupCount, seriousEventCount, otherEventCount, plus topEvents — the most frequent events ranked by participants affected, aggregated across arms (term, organSystem, kind, numAffected, numAtRisk). Full mode: adds eventGroups, seriousEvents, otherEvents with per-event term and per-group affected/at-risk stats."
      • addedOutput schema / properties / results / items / properties / moreInfo
        Added value: +{
        +  "additionalProperties": {},
        +  "description": "Results metadata from moreInfoModule. Summary mode: limitationsAndCaveats, certainAgreement flags (piSponsorEmployee, restrictiveAgreement, restrictionType), and pointOfContact. Full mode: adds certainAgreement.otherDetails.",
        +  "propertyNames": {
        +    "type": "string"
        +  },
        +  "type": "object"
        +}
    • Changedclinicaltrials_search_studies1 field changed
      • changedOutput schema / properties / searchCriteria / description
        Previous value: -"Echo of active query/filter criteria. Present when results are empty."New value: +"Echo of active query/filter criteria applied to this search, including sentinelFilterActive when the default unknown-enrollment exclusion is in effect. Present on every response."
  10. 4 tool updatesv2.5.4
    • Changedclinicaltrials_find_eligible4 fields changed
      • changedOutput schema / properties / funnel / description
        Previous value: -"Match counts at each filter stage. Diagnoses where the funnel collapsed on sparse results — e.g., conditionMatched=298 but demographicsMatched=2 means age/sex/status are the constraint."New value: +"Match counts at each filter stage. Shows where the funnel collapsed — e.g., conditionMatched=298 but demographicsMatched=2 means age/sex/status are the constraint."
      • removedOutput schema / properties / noMatchHints
        Removed value: -{
        -  "description": "Hints when no studies match, with suggestions to broaden the search.",
        -  "items": {
        -    "type": "string"
        -  },
        -  "type": "array"
        -}
      • addedOutput schema / properties / notice
        Added value: +{
        +  "description": "Recovery guidance when no studies matched — identifies which filter stage collapsed and suggests how to broaden. Absent when results are returned.",
        +  "type": "string"
        +}
      • changedOutput schema / properties / searchCriteria / description
        Previous value: -"Search criteria used."New value: +"Normalized search criteria applied to this eligibility query."
    • Changedclinicaltrials_get_field_definitions2 fields changed
      • addedOutput schema / properties / notice
        Added value: +{
        +  "description": "Recovery guidance when search mode returns no matches — suggests alternative keywords.",
        +  "type": "string"
        +}
      • changedOutput schema / properties / searchQuery / description
        Previous value: -"Echo of the keyword when mode is \"search\"."New value: +"Echo of the keyword used in search mode. Absent for drill and overview."
    • Changedclinicaltrials_get_study_count3 fields changed
      • removedOutput schema / properties / noMatchHints
        Removed value: -{
        -  "description": "Suggestions when no studies match (totalCount is 0).",
        -  "items": {
        -    "type": "string"
        -  },
        -  "type": "array"
        -}
      • addedOutput schema / properties / notice
        Added value: +{
        +  "description": "Recovery guidance when totalCount is 0 — suggests how to broaden the query or filters.",
        +  "type": "string"
        +}
      • changedOutput schema / properties / searchCriteria / description
        Previous value: -"Echo of query/filter criteria used."New value: +"Echo of active query/filter criteria applied to this count."
    • Changedclinicaltrials_search_studies3 fields changed
      • removedOutput schema / properties / noMatchHints
        Removed value: -{
        -  "description": "Suggestions for broadening the search when no results are found.",
        -  "items": {
        -    "type": "string"
        -  },
        -  "type": "array"
        -}
      • addedOutput schema / properties / notice
        Added value: +{
        +  "description": "Recovery guidance when no studies matched — echoes the constraint and suggests how to broaden. Absent on pages with results.",
        +  "type": "string"
        +}
      • changedOutput schema / properties / searchCriteria / description
        Previous value: -"Echo of query/filter criteria used. Present when results are empty."New value: +"Echo of active query/filter criteria. Present when results are empty."
  11. 7 tool updatesv2.5.1
    • Addedclinicaltrials_find_eligible
    • Addedclinicaltrials_get_field_definitions
    • Addedclinicaltrials_get_field_values
    • Addedclinicaltrials_get_study_count
    • Addedclinicaltrials_get_study_record
    • Addedclinicaltrials_get_study_results
    • Addedclinicaltrials_search_studies
  12. 7 tool updatesv2.4.12
    • Removedclinicaltrials_find_eligible
    • Removedclinicaltrials_get_field_definitions
    • Removedclinicaltrials_get_field_values
    • Removedclinicaltrials_get_study_count
    • Removedclinicaltrials_get_study_record
    • Removedclinicaltrials_get_study_results
    • Removedclinicaltrials_search_studies
  13. 9 tool updatesv2.0.6
    • Removedclinicaltrials_analyze_trends
    • Addedclinicaltrials_find_eligible
    • Addedclinicaltrials_get_field_definitions
    • Addedclinicaltrials_get_field_values
    • Removedclinicaltrials_get_study
    • Addedclinicaltrials_get_study_count
    • Addedclinicaltrials_get_study_record
    • Addedclinicaltrials_get_study_results
    • Changedclinicaltrials_search_studies32 fields changed
      • removedInput schema / additionalProperties
        Removed value: -false
      • addedInput schema / properties / advancedFilter
        Added value: +{
        +  "description": "Advanced filter using AREA[] Essie syntax. E.g., \"AREA[StudyType]INTERVENTIONAL\", \"AREA[EnrollmentCount]RANGE[100, 1000]\". Combine with AND/OR/NOT and parentheses.",
        +  "type": "string"
        +}
      • addedInput schema / properties / conditionQuery
        Added value: +{
        +  "description": "Condition/disease-specific search. E.g., \"Type 2 Diabetes\", \"non-small cell lung cancer\".",
        +  "type": "string"
        +}
      • addedInput schema / properties / countTotal
        Added value: +{
        +  "default": true,
        +  "description": "Include total study count in response. Only computed on the first page.",
        +  "type": "boolean"
        +}
      • changedInput schema / properties / fields / description
        Previous value: -"A list of specific top-level fields to include in the response."New value: +"Fields to return (PascalCase piece names). Strongly recommended to reduce payload. Common: NCTId, BriefTitle, OverallStatus, Phase, LeadSponsorName, Condition, InterventionName, BriefSummary, EnrollmentCount, StartDate."
      • removedInput schema / properties / filter
        Removed value: -{
        -  "additionalProperties": false,
        -  "description": "A set of filters that narrow the search results without affecting ranking.",
        -  "properties": {
        -    "advanced": {
        -      "description": "Apply an advanced filter using Essie expression syntax.",
        -      "type": "string"
        -    },
        -    "geo": {
        -      "additionalProperties": false,
        -      "description": "Filter results to a geographic area by providing a point and radius.",
        -      "properties": {
        -        "latitude": {
        -          "maximum": 90,
        -          "minimum": -90,
        -          "type": "number"
        -        },
        -        "longitude": {
        -          "maximum": 180,
        -          "minimum": -180,
        -          "type": "number"
        -        },
        -        "radius": {
        -          "exclusiveMinimum": 0,
        -          "type": "number"
        -        },
        -        "unit": {
        -          "default": "km",
        -          "enum": [
        -            "km",
        -            "mi"
        -          ],
        -          "type": "string"
        -        }
        -      },
        -      "required": [
        -        "latitude",
        -        "longitude",
        -        "radius"
        -      ],
        -      "type": "object"
        -    },
        -    "ids": {
        -      "description": "Return only studies with the specified NCT IDs.",
        -      "items": {
        -        "type": "string"
        -      },
        -      "type": "array"
        -    },
        -    "overallStatus": {
        -      "description": "Filter results by one or more study statuses.",
        -      "items": {
        -        "enum": [
        -          "ACTIVE_NOT_RECRUITING",
        -          "COMPLETED",
        -          "ENROLLING_BY_INVITATION",
        -          "NOT_YET_RECRUITING",
        -          "RECRUITING",
        -          "SUSPENDED",
        -          "TERMINATED",
        -          "WITHDRAWN",
        -          "UNKNOWN"
        -        ],
        -        "type": "string"
        -      },
        -      "type": "array"
        -    }
        -  },
        -  "type": "object"
        -}
      • addedInput schema / properties / geoFilter
        Added value: +{
        +  "description": "Geographic proximity filter. Format: distance(lat,lon,radius). E.g., \"distance(47.6062,-122.3321,50mi)\" for studies within 50 miles of Seattle.",
        +  "type": "string"
        +}
      • addedInput schema / properties / interventionQuery
        Added value: +{
        +  "description": "Intervention/treatment search. E.g., \"pembrolizumab\", \"cognitive behavioral therapy\".",
        +  "type": "string"
        +}
      • addedInput schema / properties / locationQuery
        Added value: +{
        +  "description": "Location search — city, state, country, or facility name.",
        +  "type": "string"
        +}
      • addedInput schema / properties / nctIds
        Added value: +{
        +  "anyOf": [
        +    {
        +      "pattern": "^NCT\\d{8}$",
        +      "type": "string"
        +    },
        +    {
        +      "items": {
        +        "pattern": "^NCT\\d{8}$",
        +        "type": "string"
        +      },
        +      "type": "array"
        +    }
        +  ],
        +  "description": "Filter to specific NCT IDs for batch lookups."
        +}
      • addedInput schema / properties / outcomeQuery
        Added value: +{
        +  "description": "Search within outcome measure fields.",
        +  "type": "string"
        +}
      • changedInput schema / properties / pageSize / description
        Previous value: -"The number of studies to return per page (1-200). Defaults to 10."New value: +"Results per page, 1–200."
      • changedInput schema / properties / pageToken / description
        Previous value: -"A token used to retrieve the next page of results."New value: +"Pagination cursor from a previous response."
      • addedInput schema / properties / phaseFilter
        Added value: +{
        +  "anyOf": [
        +    {
        +      "type": "string"
        +    },
        +    {
        +      "items": {
        +        "type": "string"
        +      },
        +      "type": "array"
        +    }
        +  ],
        +  "description": "Filter by trial phase. Values: EARLY_PHASE1, PHASE1, PHASE2, PHASE3, PHASE4, NA."
        +}
      • removedInput schema / properties / query / additionalProperties
        Removed value: -false
      • changedInput schema / properties / query / description
        Previous value: -"A set of search terms that influence result ranking."New value: +"General full-text search across all fields."
      • removedInput schema / properties / query / properties
        Removed value: -{
        -  "cond": {
        -    "description": "Search for conditions or diseases.",
        -    "type": "string"
        -  },
        -  "id": {
        -    "description": "Search for study identifiers (e.g., NCT ID).",
        -    "type": "string"
        -  },
        -  "intr": {
        -    "description": "Search for specific interventions or treatments.",
        -    "type": "string"
        -  },
        -  "locn": {
        -    "description": "Search for study locations.",
        -    "type": "string"
        -  },
        -  "outc": {
        -    "description": "Search for specific outcome measures.",
        -    "type": "string"
        -  },
        -  "spons": {
        -    "description": "Search for sponsors or collaborators.",
        -    "type": "string"
        -  },
        -  "term": {
        -    "description": "Search for other terms like interventions, outcomes, or sponsors.",
        -    "type": "string"
        -  },
        -  "titles": {
        -    "description": "Search within study titles or acronyms.",
        -    "type": "string"
        -  }
        -}
      • changedInput schema / properties / query / type
        Previous value: -"object"New value: +"string"
      • changedInput schema / properties / sort / description
        Previous value: -"Specify the sort order for the results."New value: +"Sort order. Format: FieldName:asc or FieldName:desc. E.g., \"LastUpdatePostDate:desc\", \"EnrollmentCount:desc\". Max 2 fields comma-separated."
      • removedInput schema / properties / sort / items
        Removed value: -{
        -  "type": "string"
        -}
      • changedInput schema / properties / sort / type
        Previous value: -"array"New value: +"string"
      • addedInput schema / properties / sponsorQuery
        Added value: +{
        +  "description": "Sponsor/collaborator name search.",
        +  "type": "string"
        +}
      • addedInput schema / properties / statusFilter
        Added value: +{
        +  "anyOf": [
        +    {
        +      "type": "string"
        +    },
        +    {
        +      "items": {
        +        "type": "string"
        +      },
        +      "type": "array"
        +    }
        +  ],
        +  "description": "Filter by study status. Values: RECRUITING, COMPLETED, ACTIVE_NOT_RECRUITING, NOT_YET_RECRUITING, ENROLLING_BY_INVITATION, SUSPENDED, TERMINATED, WITHDRAWN, UNKNOWN, WITHHELD, NO_LONGER_AVAILABLE, AVAILABLE, APPROVED_FOR_MARKETING, TEMPORARILY_NOT_AVAILABLE."
        +}
      • addedInput schema / properties / titleQuery
        Added value: +{
        +  "description": "Search within study titles and acronyms only.",
        +  "type": "string"
        +}
      • addedOutput schema / properties / nextPageToken / description
        Added value: +"Token for the next page. Absent on last page."
      • addedOutput schema / properties / noMatchHints
        Added value: +{
        +  "description": "Suggestions for broadening the search when no results are found.",
        +  "items": {
        +    "type": "string"
        +  },
        +  "type": "array"
        +}
      • addedOutput schema / properties / searchCriteria
        Added value: +{
        +  "additionalProperties": {},
        +  "description": "Echo of query/filter criteria used. Present when results are empty.",
        +  "propertyNames": {
        +    "type": "string"
        +  },
        +  "type": "object"
        +}
      • addedOutput schema / properties / studies / description
        Added value: +"Matching studies."
      • changedOutput schema / properties / studies / items / additionalProperties
        Previous value: -trueNew value: +{}
      • removedOutput schema / properties / studies / items / properties
        Removed value: -{
        -  "derivedSection": {
        -    "additionalProperties": true,
        -    "properties": {
        -      "conditionBrowseModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "ancestors": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "id": {
        -                  "type": "string"
        -                },
        -                "term": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          },
        -          "browseBranches": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "abbrev": {
        -                  "type": "string"
        -                },
        -                "name": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          },
        -          "browseLeaves": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "asFound": {
        -                  "type": "string"
        -                },
        -                "id": {
        -                  "type": "string"
        -                },
        -                "name": {
        -                  "type": "string"
        -                },
        -                "relevance": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          },
        -          "meshes": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "id": {
        -                  "type": "string"
        -                },
        -                "term": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          }
        -        },
        -        "type": "object"
        -      },
        -      "interventionBrowseModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "ancestors": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "id": {
        -                  "type": "string"
        -                },
        -                "term": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          },
        -          "browseBranches": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "abbrev": {
        -                  "type": "string"
        -                },
        -                "name": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          },
        -          "browseLeaves": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "id": {
        -                  "type": "string"
        -                },
        -                "name": {
        -                  "type": "string"
        -                },
        -                "relevance": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          },
        -          "meshes": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "id": {
        -                  "type": "string"
        -                },
        -                "term": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          }
        -        },
        -        "type": "object"
        -      },
        -      "miscInfoModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "versionHolder": {
        -            "type": "string"
        -          }
        -        },
        -        "type": "object"
        -      }
        -    },
        -    "type": "object"
        -  },
        -  "hasResults": {
        -    "type": "boolean"
        -  },
        -  "protocolSection": {
        -    "additionalProperties": true,
        -    "properties": {
        -      "armsInterventionsModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "arms": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "description": {
        -                  "type": "string"
        -                },
        -                "name": {
        -                  "type": "string"
        -                },
        -                "type": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          },
        -          "interventions": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "armNames": {
        -                  "items": {
        -                    "type": "string"
        -                  },
        -                  "type": "array"
        -                },
        -                "description": {
        -                  "type": "string"
        -                },
        -                "name": {
        -                  "type": "string"
        -                },
        -                "type": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          }
        -        },
        -        "type": "object"
        -      },
        -      "conditionsModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "conditions": {
        -            "items": {
        -              "type": "string"
        -            },
        -            "type": "array"
        -          },
        -          "keywords": {
        -            "items": {
        -              "type": "string"
        -            },
        -            "type": "array"
        -          }
        -        },
        -        "type": "object"
        -      },
        -      "contactsLocationsModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "locations": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "city": {
        -                  "type": "string"
        -                },
        -                "country": {
        -                  "type": "string"
        -                },
        -                "state": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          }
        -        },
        -        "type": "object"
        -      },
        -      "descriptionModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "briefSummary": {
        -            "type": "string"
        -          },
        -          "detailedDescription": {
        -            "type": "string"
        -          }
        -        },
        -        "type": "object"
        -      },
        -      "designModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "designInfo": {
        -            "additionalProperties": true,
        -            "properties": {
        -              "allocation": {
        -                "type": "string"
        -              },
        -              "interventionModel": {
        -                "type": "string"
        -              },
        -              "maskingInfo": {
        -                "additionalProperties": true,
        -                "properties": {
        -                  "masking": {
        -                    "type": "string"
        -                  }
        -                },
        -                "type": "object"
        -              },
        -              "primaryPurpose": {
        -                "type": "string"
        -              }
        -            },
        -            "type": "object"
        -          },
        -          "phases": {
        -            "items": {
        -              "type": "string"
        -            },
        -            "type": "array"
        -          },
        -          "studyType": {
        -            "type": "string"
        -          }
        -        },
        -        "type": "object"
        -      },
        -      "eligibilityModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "eligibilityCriteria": {
        -            "type": "string"
        -          },
        -          "healthyVolunteers": {
        -            "type": "boolean"
        -          },
        -          "minimumAge": {
        -            "type": "string"
        -          },
        -          "sex": {
        -            "type": "string"
        -          },
        -          "stdAges": {
        -            "items": {
        -              "type": "string"
        -            },
        -            "type": "array"
        -          }
        -        },
        -        "type": "object"
        -      },
        -      "identificationModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "acronym": {
        -            "type": "string"
        -          },
        -          "briefTitle": {
        -            "type": "string"
        -          },
        -          "nctId": {
        -            "type": "string"
        -          },
        -          "officialTitle": {
        -            "type": "string"
        -          },
        -          "orgStudyIdInfo": {
        -            "additionalProperties": true,
        -            "properties": {
        -              "id": {
        -                "type": "string"
        -              }
        -            },
        -            "type": "object"
        -          },
        -          "organization": {
        -            "additionalProperties": true,
        -            "properties": {
        -              "class": {
        -                "type": "string"
        -              },
        -              "fullName": {
        -                "type": "string"
        -              }
        -            },
        -            "type": "object"
        -          }
        -        },
        -        "required": [
        -          "nctId"
        -        ],
        -        "type": "object"
        -      },
        -      "sponsorCollaboratorsModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "collaborators": {
        -            "items": {
        -              "additionalProperties": true,
        -              "properties": {
        -                "class": {
        -                  "type": "string"
        -                },
        -                "name": {
        -                  "type": "string"
        -                }
        -              },
        -              "type": "object"
        -            },
        -            "type": "array"
        -          },
        -          "leadSponsor": {
        -            "additionalProperties": true,
        -            "properties": {
        -              "class": {
        -                "type": "string"
        -              },
        -              "name": {
        -                "type": "string"
        -              }
        -            },
        -            "type": "object"
        -          },
        -          "responsibleParty": {
        -            "additionalProperties": true,
        -            "properties": {
        -              "type": {
        -                "type": "string"
        -              }
        -            },
        -            "type": "object"
        -          }
        -        },
        -        "type": "object"
        -      },
        -      "statusModule": {
        -        "additionalProperties": true,
        -        "properties": {
        -          "completionDateStruct": {
        -            "additionalProperties": true,
        -            "properties": {
        -              "date": {
        -                "type": "string"
        -              },
        -              "type": {
        -                "type": "string"
        -              }
        -            },
        -            "type": "object"
        -          },
        -          "lastKnownStatus": {
        -            "type": "string"
        -          },
        -          "overallStatus": {
        -            "type": "string"
        -          },
        -          "primaryCompletionDateStruct": {
        -            "additionalProperties": true,
        -            "properties": {
        -              "date": {
        -                "type": "string"
        -              },
        -              "type": {
        -                "type": "string"
        -              }
        -            },
        -            "type": "object"
        -          },
        -          "startDateStruct": {
        -            "additionalProperties": true,
        -            "properties": {
        -              "date": {
        -                "type": "string"
        -              },
        -              "type": {
        -                "type": "string"
        -              }
        -            },
        -            "type": "object"
        -          }
        -        },
        -        "type": "object"
        -      }
        -    },
        -    "type": "object"
        -  }
        -}
      • addedOutput schema / properties / studies / items / propertyNames
        Added value: +{
        +  "type": "string"
        +}
      • addedOutput schema / properties / totalCount / description
        Added value: +"Total matching studies (first page only when countTotal=true)."
  14. 3 tool updatesv1.0.0
    • First observedclinicaltrials_analyze_trends
    • First observedclinicaltrials_get_study
    • First observedclinicaltrials_search_studies

TDQS

A4.3/5.0

Scored across 7 tools

Disambiguation5/5

Each tool targets a distinct operation: search, count, full record, results data, eligibility matching, field-value discovery, and field-name resolution. Overlap between metadata tools is minimal and clearly resolved by their descriptions.

Naming Consistency5/5

All tools use a consistent clinicaltrials_ prefix with snake_case and a predictable verb_noun structure. The one slight variation, find_eligible, is still clear and follows the same prefix convention.

Tool Count5/5

Seven tools is well-scoped for the ClinicalTrials.gov domain, with each tool covering a distinct and useful operation. No tool feels redundant or out of place.

Completeness5/5

The set covers search, count, full study retrieval, results data, field metadata, and patient eligibility matching. For a read-only clinical trials API, this provides a complete lifecycle without obvious dead ends.

Maintenance

ActivityActive
ResponsivenessResponsive

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