Enrichr MCP Server
Server Configuration
Describes the environment variables required to run the server.
| Name | Required | Description | Default |
|---|---|---|---|
| ENRICHR_FORMAT | No | Output format: detailed, compact, or minimal | detailed |
| ENRICHR_LIBRARIES | No | Comma-separated list of Enrichr libraries to query | pop |
| ENRICHR_MAX_TERMS | No | Maximum number of terms to show per library | 50 |
| ENRICHR_OUTPUT_FILE | No | Path to save complete results as TSV file |
Instructions
Guidance the server publishes about itself, which clients place ahead of the tool catalog so the model reads it before choosing anything.
This server publishes no instructions, or was last inspected before Glama recorded them.
Capabilities
Features and capabilities supported by this server
Protocol revision2025-11-25
| Capability | Details |
|---|---|
| tools | {
"listChanged": true
} |
| prompts | {
"listChanged": true
} |
| resources | {
"listChanged": true
} |
| completions | {} |
Tools
Functions exposed to the LLM to take actions
| Name | Description |
|---|---|
| enrichr_analysis | Perform gene set enrichment analysis using Enrichr across multiple gene set libraries. Returns only statistically significant terms (adjusted p < 0.05). Configured default libraries:
Any library in Enrichr's live catalog is accepted. Enrichr adds and retires libraries continuously, so do not rely on a memorized list: call suggest_libraries, or read the enrichr://libraries resource, to discover the libraries that currently exist. Pass 'background' to test against a custom background gene set (for example, only the genes expressed in your assay) instead of Enrichr's whole-genome default. This is the statistically correct choice whenever the gene list was drawn from a restricted universe, and it matters: the whole-genome default can overstate significance by many orders of magnitude. Each library's result reports 'backgroundCorrected'. If Enrichr's background service is unavailable the result falls back to uncorrected whole-genome p-values, flagged with a warning — treat those numbers as inflated and re-run rather than reporting them as background-corrected. |
| suggest_librariesA | Suggest relevant Enrichr libraries for a research question. Use this before enrichr_analysis to pick the best libraries for a specific topic. |
Prompts
Interactive templates invoked by user choice
| Name | Description |
|---|---|
| enrichment_analysis | Guided workflow for gene set enrichment analysis with library selection and interpretation |
Resources
Contextual data attached and managed by the client
| Name | Description |
|---|---|
| library_catalog | All available Enrichr libraries organized by category |
| transcription libraries | Libraries for a specific category |
| pathways libraries | Libraries for a specific category |
| ontologies libraries | Libraries for a specific category |
| diseases_drugs libraries | Libraries for a specific category |
| cell_types libraries | Libraries for a specific category |
| microRNAs libraries | Libraries for a specific category |
| epigenetics libraries | Libraries for a specific category |
| kinases libraries | Libraries for a specific category |
| gene_perturbations libraries | Libraries for a specific category |
| metabolomics libraries | Libraries for a specific category |
| aging libraries | Libraries for a specific category |
| protein_families libraries | Libraries for a specific category |
| computational libraries | Libraries for a specific category |
| literature libraries | Libraries for a specific category |
| cancer libraries | Libraries for a specific category |
| single_cell libraries | Libraries for a specific category |
| chromosome libraries | Libraries for a specific category |
| protein_interactions libraries | Libraries for a specific category |
| structural libraries | Libraries for a specific category |
| immunology libraries | Libraries for a specific category |
| development libraries | Libraries for a specific category |
| other libraries | Libraries for a specific category |
TDQS
Scored across 1 tool
With only one tool, there is no possible confusion between tools. suggest_libraries has a clearly stated purpose, though the description references enrichr_analysis, which is not provided.
The single tool name follows a clean verb_noun pattern, but with only one tool there is not enough repetition to establish a true naming convention.
A single tool called suggest_libraries is an extreme mismatch for an Enrichr server, which should also offer enrichment analysis and related operations. The tool itself even references a missing enrichr_analysis tool.
The server is severely incomplete for its stated domain. It only suggests libraries and provides no way to run enrichment analysis or otherwise interact with Enrichr.