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mosaic_target_mechanisms

Read-onlyIdempotent

Retrieve mechanism-of-action profiles for drug targets, including compound interactions and semantic evidence from literature.

Instructions

Get the mechanism-of-action profile for a drug target.

Returns how compounds interact with this target — inhibitors (covalent, allosteric, competitive), agonists, antagonists, degraders (PROTAC). Also shows semantic edge types: validation evidence, resistance mechanisms, biomarker roles, safety concerns, and clinical efficacy signals.

Extracted by GLiREL from paper and patent abstracts.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
paramsYes

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
resultYes
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already indicate readOnlyHint, idempotentHint, destructiveHint. Description adds that results are extracted from papers/patents via GLiREL, which discloses the source and limitations.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Two clear paragraphs with front-loaded purpose and systematic listing of output types. No fluff.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

For a read-only query tool with output schema and annotations, description covers purpose, extracted data types, and source. Lacks mention of pagination or limits, but acceptable.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema coverage is 0% per context, but description mentions 'target' implicitly. The parameter gene_symbol is well-described in the schema itself, so description adds minimal value.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

Description clearly states it retrieves mechanism-of-action profile for a drug target, listing specific interaction types and semantic edge types, distinguishing it from siblings like mosaic_get_target_compounds or mosaic_evidence_map.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines3/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

Usage is implied through description of output (mechanisms, edge types), but no explicit guidance on when to use vs. alternatives or when not to use.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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