Zetesis

Scientific due diligence on a claim, from inside Claude, Copilot, or any MCP host.

Zetesis takes a high-dimensional scientific or technical claim and grades it dimension by dimension against public literature, clinical trials, and filings. It returns an overall reading, cites every source by id, and, for a full evaluation, translates the science into what a commitment to the claim turns on and seals the result in an attestation anyone can re-check.

This package is a thin MCP client. It holds no keys and runs no model. Every call is proxied to the hosted engine at https://api.zetesis.science with your token.

Get a token

Free, no card, at https://api.zetesis.science/signup. The free plan gives you a handful of screening evaluations each month.

Related MCP server: biopharma-catalyst-mcp

Connect it

Claude Code:

claude mcp add zetesis --env ZETESIS_TOKEN=zk_... -- uvx --from zetesis zetesis-client

Claude Desktop (claude_desktop_config.json):

{
  "mcpServers": {
    "zetesis": {
      "command": "uvx",
      "args": ["--from", "zetesis", "zetesis-client"],
      "env": { "ZETESIS_TOKEN": "zk_..." }
    }
  }
}

Tools

• evaluate_claim — grade a claim. depth="screen" returns the verdict directly (free tier); depth="deep" runs the full signed dossier in the background. mode="research" is science only; mode="diligence" adds the capital reading.

• check_evaluation — get the verdict and the rendered dossier link for a deep run.

• verify_attestation — re-check any Zetesis attestation. No account needed.

• account_status — your plan and remaining evaluations or credits.

How it grades

It grades only what the evidence supports, cites sources by hard id (PMID, DOI, NCT, NIH grant, SEC filing), and flags gaps rather than filling them. It never invents citations. Claim text is not logged; only metadata (the routed domain, depth, counts) is kept.

Configuration

• ZETESIS_TOKEN — your token (required for evaluations; verify works without one)

• ZETESIS_API — override the API base (default https://api.zetesis.science)

MIT licensed. The hosted engine is a separate service.

mcp-name: io.github.reutavidan/zetesis