variants
Retrieve single-variant association results for a trait, genome-wide or within a specific gene, with per-biobank effect direction and cross-biobank replication evidence.
Instructions
Single-variant results for a trait, genome-wide or inside one gene.
Drops below the gene-level burden tests to the individual variants carrying a
signal. Without gene this ranks the whole genome for the trait; with gene
it restricts to that gene and adds the per-biobank effect-direction tally,
the cross-biobank replication evidence.
Still fetched over HTTP rather than shipped in the database: the variant-level format is a separate, actively changing upstream release, an order of magnitude larger than the gene-level table, and rebuilt often enough that a local copy would be stale within the week. Each file is cached permanently once fetched.
Each row links to gnomAD, where population allele frequencies live.
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| gene | No | Restrict to one gene. Omit for the genome-wide scan. | |
| chrom | No | Restrict the genome-wide scan to one chromosome ("2", "X"). | |
| limit | No | Max rows (default 25). | |
| max_p | No | p-value ceiling. The variant-level threshold is 1.82e-8. | |
| offset | No | Skip this many rows, to page through a long result set. | |
| ancestry | No | All (cross-ancestry meta, default) or a specific stratum. Only meaningful together with `gene`. | All |
| phenotype | Yes | Trait id or name. |
Output Schema
| Name | Required | Description | Default |
|---|---|---|---|
| result | Yes |