uniprot_search

    Available query fields (see https://www.uniprot.org/help/query-fields):
    - accession: Primary/canonical isoform accessions (e.g., accession:P62988)
    - active: Active/obsolete status (e.g., active:false)
    - lit_author: Reference author (e.g., lit_author:ashburner)
    - protein_name: Protein name (e.g., protein_name:CD233)
    - chebi: ChEBI identifier (e.g., chebi:18420)
    - xrefcount_pdb: Cross-reference count (e.g., xref_count_pdb:[20 TO *])
    - date_created: Creation date (e.g., date_created:[2012-10-01 TO *])
    - date_modified: Last modification date (e.g., date_modified:[2012-01-01 TO 2019-03-01])
    - date_sequence_modified: Sequence modification date (e.g., date_sequence_modified:[2012-01-01 TO 2012-03-01])
    - database: Database cross-reference (e.g., database:pfam)
    - xref: Cross-reference (e.g., xref:pdb-1aut)
    - ec: Enzyme Commission number (e.g., ec:3.2.1.23)
    - existence: Protein existence level (e.g., existence:3)
    - family: Protein family (e.g., family:serpin)
    - fragment: Fragment status (e.g., fragment:true)
    - gene: Gene name (e.g., gene:HPSE)
    - gene_exact: Exact gene name (e.g., gene_exact:HPSE)
    - go: Gene Ontology term (e.g., go:0015629)
    - virus_host_name: Virus host name
    - virus_host_id: Virus host ID (e.g., virus_host_id:10090)
    - accession_id: Primary accession (e.g., accession_id:P00750)
    - inchikey: InChIKey identifier (e.g., inchikey:WQZGKKKJIJFFOK-GASJEMHNSA-N)
    - interactor: Interacting protein (e.g., interactor:P00520)
    - keyword: Keyword (e.g., keyword:toxin or keyword:KW-0800)
    - length: Sequence length range (e.g., length:[500 TO 700])
    - mass: Molecular mass range (e.g., mass:[500000 TO *])
    - cc_mass_spectrometry: Mass spectrometry method (e.g., cc_mass_spectrometry:maldi)
    - encoded_in: Gene location (e.g., encoded_in:Mitochondrion)
    - organism_name: Organism name (e.g., organism_name:"Ovis aries")
    - organism_id: Organism taxonomy ID (e.g., organism_id:9940)
    - plasmid: Plasmid name (e.g., plasmid:ColE1)
    - proteome: Proteome ID (e.g., proteome:UP000005640)
    - proteomecomponent: Proteome component (e.g., proteomecomponent:"chromosome 1")
    - sec_acc: Secondary accession (e.g., sec_acc:P02023)
    - reviewed: Reviewed status (e.g., reviewed:true)
    - scope: Reference scope (e.g., scope:mutagenesis)
    - sequence: Sequence identifier (e.g., accession:P05067-9 AND is_isoform:true)
    - strain: Organism strain (e.g., strain:wistar)
    - taxonomy_name: Taxonomy name (e.g., taxonomy_name:mammal)
    - taxonomy_id: Taxonomy ID (e.g., taxonomy_id:40674)
    - tissue: Tissue type (e.g., tissue:liver)
    - cc_webresource: Web resource (e.g., cc_webresource:wikipedia)
    
database: UniProt database to search. One of: uniprotkb (default), uniparc, uniref

limit: Maximum number of results per page (1-100, default 10)

fields: Optional list of return fields to include. If not specified, all fields
    are returned. Available return fields (see https://www.uniprot.org/help/return_fields):
    
    Names & Taxonomy:
    - accession, id, gene_names, gene_primary, gene_synonym, gene_oln, gene_orf
    - organism_name, organism_id, protein_name, xref_proteomes
    - lineage, lineage_ids, virus_hosts
    
    Sequences:
    - cc_alternative_products, ft_var_seq, cc_sc_epred, fragment, encoded_in
    - length, mass, cc_mass_spectrometry, ft_variant, ft_non_cons, ft_non_std
    - ft_non_ter, cc_polymorphism, cc_rna_editing, sequence, cc_sequence_caution
    - ft_conflict, ft_unsure, sequence_version
    
    Function:
    - absorption, ft_act_site, cc_activity_regulation, ft_binding, cc_catalytic_activity
    - cc_cofactor, ft_dna_bind, ec, cc_function, kinetics, cc_pathway
    - ph_dependence, redox_potential, rhea, ft_site, temp_dependence
    
    Miscellaneous:
    - annotation_score, cc_caution, comment_count, feature_count, keywordid, keyword
    - cc_miscellaneous, protein_existence, reviewed, tools, uniparc_id
    
    Interaction:
    - cc_interaction, cc_subunit
    
    Expression:
    - cc_developmental_stage, cc_induction, cc_tissue_specificity
    
    Gene Ontology (GO):
    - go_p, go_c, go, go_f, go_id
    
    Pathology & Biotech:
    - cc_allergen, cc_biotechnology, cc_disruption_phenotype, cc_disease
    - ft_mutagen, cc_pharmaceutical, cc_toxic_dose
    
    Subcellular location:
    - ft_intramem, cc_subcellular_location, ft_topo_dom, ft_transmem
    
    PTM / Processing:
    - ft_chain, ft_crosslnk, ft_disulfid, ft_carbohyd, ft_init_met, ft_lipid
    - ft_mod_res, ft_peptide, cc_ptm, ft_propep, ft_signal, ft_transit
    
    Structure:
    - structure_3d, ft_strand, ft_helix, ft_turn
    
    Publications:
    - lit_pubmed_id
    
    Date:
    - date_created, date_modified, date_sequence_modified, version
    
    Family & Domains:
    - ft_coiled, ft_compbias, cc_domain, ft_domain, ft_motif, protein_families
    - ft_region, ft_repeat, ft_zn_fing
    
    Cross-references:
    - See https://www.uniprot.org/help/return_fields for cross-reference fields
    
cursor: Pagination cursor from a previous search result's 'nextCursor' field.
    Pass this to retrieve the next page of results.

response_format: Response format. One of: 'json' (default) or 'toon'.
    - 'json': Returns response in JSON format
    - 'toon': Returns response in TOON format

When response_format='toon': TOON-formatted string with:
- results: Array of matching protein entries
- total: Total number of matching entries (if available)
- nextCursor: Cursor string for retrieving the next page (if more results exist)