cost_effectiveness_model
Build cost-utility analyses for drug comparisons using Markov models, probabilistic sensitivity analysis, and adherence to ISPOR/NICE guidelines to determine cost-effectiveness.
Instructions
Build a cost-utility analysis (ICER, QALY, PSA, sensitivity analysis) for a drug vs comparator. Follows ISPOR good practice guidelines and NICE reference case. Includes probabilistic sensitivity analysis (PSA), one-way sensitivity, and cost-effectiveness acceptability curve (CEAC).
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| intervention | Yes | Drug or treatment name | |
| comparator | Yes | Comparator (standard of care) | |
| indication | Yes | Disease or condition | |
| time_horizon | Yes | Modelling horizon: 'lifetime', '5yr', '10yr', or years as number | |
| perspective | Yes | ||
| model_type | No | Model type. Default: markov. Use 'partsa' for oncology. | |
| clinical_inputs | Yes | ||
| cost_inputs | Yes | ||
| utility_inputs | No | ||
| run_psa | No | Run probabilistic sensitivity analysis (default: true) | |
| psa_iterations | No | PSA iterations (default: 1000, max: 10000) | |
| output_format | No | ||
| project | No | Project ID for knowledge base persistence. When set, model run is saved to ~/.heor-agent/projects/{project}/raw/models/ |