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mihir19

bioevidence-mcp

by mihir19

BioEvidence MCP

Evidence-grounded biomedical retrieval and summarization through the Model Context Protocol.

Repository: github.com/mihir19/bioevidence-mcp

The distribution name is bioevidence-mcp. The Python import namespace remains bioreason for backward compatibility with existing integrations.

Research use only. No diagnosis, treatment recommendations, or patient data.

Setup

Install Python 3.12 and uv, then install the project dependencies:

uv sync

Related MCP server: MedAdapt Content Server

Manual testing

Call the health tool directly through FastMCP:

uv run fastmcp call src/bioreason/server.py health

The structured result should be:

{
  "status": "ok",
  "version": "0.1.1"
}

To run the MCP server over the default stdio transport:

uv run fastmcp run src/bioreason/server.py:mcp

Evaluation

Run the deterministic, network-free release gate:

uv run python -m bioreason.evaluation.runner \
  --mode offline \
  --output evaluation/reports/offline-report.json \
  --markdown evaluation/reports/offline-report.md

Run one explicitly selected live integration case:

uv run --env-file .env python -m bioreason.evaluation.runner \
  --mode live \
  --case-id brca1-c68-69delag \
  --output evaluation/reports/live-brca1.json \
  --markdown evaluation/reports/live-brca1.md

Offline evaluation is deterministic and CI-safe. Live evaluation requires network access, and exact evidence counts may change. OpenAI is optional: missing summarizer configuration produces an incomplete integration case without losing retrieval results. Evaluation establishes citation provenance and eligibility, not clinical validity or complete semantic entailment. See evaluation/README.md.

Available Tools

2 tools
healthA

Return stable service health metadata.

ParametersJSON Schema
NameRequiredDescriptionDefault

No parameters

Output Schema

ParametersJSON Schema
NameRequiredDescription

No output parameters

TDQS

A4/5.0
Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

No annotations provided. Description indicates 'stable' metadata, implying non-destructive and consistent behavior. However, additional details like rate limits or performance impact are absent.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Description is a single, concise sentence with no wasted words. It effectively communicates the tool's function.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Tool is simple with no parameters and an output schema present. The description is adequate for a health endpoint, though it could mention typical use cases like monitoring.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters4/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema has 0 parameters with 100% coverage. Description adds no parameter information, which is acceptable as there are none. Baseline is 4.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

Description clearly states the tool returns stable service health metadata. Distinguishes from sibling tool 'search_biomedical_evidence' which has a different purpose.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines3/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

No explicit when-to-use or when-not-to-use instructions. Usage is implied as a health check, but no alternatives or exclusions are mentioned.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

search_biomedical_evidenceC

Retrieve, score, group, and optionally summarize biomedical evidence.

ParametersJSON Schema
NameRequiredDescriptionDefault
queryYes
include_summaryNo
max_results_per_sourceNo

Output Schema

ParametersJSON Schema
NameRequiredDescription

No output parameters

TDQS

C2.6/5.0
Behavior2/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

With no annotations, the description must disclose behavioral traits such as safety (read-only vs. destructive), authentication needs, or side effects. It only lists generic actions; for example, it doesn't clarify if 'score' and 'group' imply state changes or are purely analytical.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness3/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Single sentence is concise and front-loaded with the core action, but it omits critical details that could be included without length increase. It earns its place but is insufficiently informative.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness2/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Despite having an output schema (unseen), the description lacks context on data sources, scoring methodology, grouping logic, and summary format. For a tool with 3 parameters and no annotations, the description is too sparse to fully understand its capabilities.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters2/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 0%, so the description must compensate. 'optionally summarize' hints at include_summary, but 'query' and 'max_results_per_source' are not explained. Additionally, 'group' is mentioned but no grouping parameter exists, causing confusion.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

Description uses specific verbs (retrieve, score, group, summarize) and resource (biomedical evidence), giving a clear sense of functionality. However, it lacks differentiation from the sibling tool 'health' and doesn't specify what constitutes 'evidence' (e.g., literature types, databases).

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines2/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

No guidance on when to use this tool versus the sibling 'health' or other alternatives. The description does not state prerequisites or contextual cues for invocation.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

TDQS

C2.9/5.0
Disambiguation5/5

The health and search tools serve completely different purposes—one for service health, the other for querying evidence—so there is no ambiguity.

Naming Consistency2/5

One tool uses a short noun ('health'), while the other uses a verb_noun pattern with underscores ('search_biomedical_evidence'), showing inconsistent naming conventions.

Tool Count2/5

With only two tools and one being a simple health check, the server feels underdeveloped for the domain of biomedical evidence retrieval, suggesting more tools are needed.

Completeness2/5

The search tool provides a broad query capability, but lacks supporting tools for retrieving specific evidence items, managing sources, or performing other typical operations in the domain.

Maintenance

ActivitySlowing
ResponsivenessSyncing

Resources

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