Skip to main content
Glama

smiles_replace

Replace a SMARTS pattern in a SMILES string with a given replacement SMARTS pattern.

Instructions

Replace SMARTS pattern in a SMILES

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
molYes
target_smartsYes
replacement_smartsYes

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
resultYes
Behavior2/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

With no annotations, the description should disclose behavioral traits, but it only states the basic operation. It does not mention whether replacements are global or single, case sensitivity, or any side effects.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness3/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is a single brief sentence, which is concise but lacks sufficient detail. While front-loaded, it could be more structured to include key information.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness2/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given three required parameters and no schema descriptions, the tool requires more context. Even though an output schema exists, the description fails to cover usage, constraints, or behavior, making it incomplete.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters1/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 0%, so the description must compensate by explaining parameters. However, it mentions no parameter details, leaving 'mol', 'target_smarts', and 'replacement_smarts' entirely undefined.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the verb 'Replace' and the resource 'SMARTS pattern in a SMILES', distinguishing it from sibling tools like smiles_remove or smiles_react, which handle different operations.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines2/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

No guidance is provided on when to use this tool versus alternatives, such as when to replace rather than remove or react a pattern. The description lacks context for appropriate usage.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

Install Server

Other Tools

Latest Blog Posts

MCP directory API

We provide all the information about MCP servers via our MCP API.

curl -X GET 'https://glama.ai/api/mcp/v1/servers/lukasmki/mol-mcp'

If you have feedback or need assistance with the MCP directory API, please join our Discord server