get_variant_annotations
Retrieve comprehensive biological annotation values for a genetic variant, including reference and alternate allele predictions across 325 annotations. Filter by category for targeted analysis.
Instructions
Get detailed annotation probe values for a variant.
Returns the Evo 2 model's predicted annotation values for both the reference and alternate allele across 325 biological annotations. Each annotation shows ref (reference allele prediction), alt (alternate allele prediction), and delta (alt - ref).
Use this for deep analysis when you need the full picture — e.g., all chromatin marks across tissues, all amino acid probabilities, or every protein feature prediction. For a quick ranked view of what's most disrupted, use get_variant_disruptions instead.
Args: variant_id: Variant identifier in chr:pos:ref:alt format. category: Optional filter. One of: amino_acid, atacseq, ccre, chipseq, chromhmm, elm, fstack, protein_feature, interpro, genomic_feature, ptm, region, secondary_structure. Omit to get ALL annotations.
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| variant_id | Yes | ||
| category | No |