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cyanheads

@cyanheads/gnomad-genetics-mcp-server

by cyanheads

Server Configuration

Describes the environment variables required to run the server.

NameRequiredDescriptionDefault
NCBI_API_KEYNoOptional NCBI key. Raises the E-utilities rate limit from 3 to 10 req/s.
OTEL_ENABLEDNoEnable OpenTelemetry instrumentation.false
MCP_AUTH_MODENoAuth mode: none, jwt, or oauth.none
MCP_HTTP_PORTNoPort for the HTTP server.3010
MCP_LOG_LEVELNoLog level (RFC 5424).info
CLINVAR_BASE_URLNoNCBI E-utilities base URL for gnomad_search_clinvar.https://eutils.ncbi.nlm.nih.gov/entrez/eutils
MCP_TRANSPORT_TYPENoTransport: stdio or http.stdio
GNOMAD_API_BASE_URLNognomAD GraphQL endpoint. Override for a private mirror or testing.https://gnomad.broadinstitute.org/api
CANVAS_PROVIDER_TYPENoSet to duckdb to enable the spill/SQL path behind the list tools. When none, they return a capped inline preview.none
GNOMAD_DEFAULT_DATASETNoDataset used when a tool call omits dataset (gnomad_r4 / gnomad_r3 / gnomad_r2_1 / exac).gnomad_r4
GNOMAD_MAX_CONCURRENCYNoCap on concurrent upstream requests — politeness against a community-funded API.2
GNOMAD_MAX_VARIANT_BATCHNoMaximum variant IDs accepted per gnomad_get_variant call.25
GNOMAD_REQUEST_TIMEOUT_MSNoPer-request timeout against the GraphQL endpoint, in milliseconds.30000
GNOMAD_DATAFRAME_DROP_ENABLEDNoGate for the opt-in gnomad_dataframe_drop tool. Off by default.false

Capabilities

Server capabilities have not been inspected yet.

Tools

Functions exposed to the LLM to take actions

NameDescription

No tools

Prompts

Interactive templates invoked by user choice

NameDescription

No prompts

Resources

Contextual data attached and managed by the client

NameDescription

No resources

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