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Search Genes

search_genes
Read-onlyIdempotent

Search gene symbols, names, and aliases with free-text queries. Returns relevance-ranked gene summaries including HGNC ID, symbol, name, and locus type.

Instructions

Free-text search over gene symbols, names, aliases, and previous symbols (FTS, relevance-ranked). Returns ranked {hgnc_id, symbol, name, locus_type, score} summaries. Nomenclature-only: there is NO disease/phenotype semantics, so a descriptive query (e.g. 'polycystin kidney') only matches words present in a gene's nomenclature. Use resolve_symbol for an exact symbol/id; use this for partial names. Signature: search_genes(query, limit=, response_mode=).

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
limitNoMax hits (default 25).
queryYesFree-text query (symbol fragment, name, alias).
response_modeNoVerbosity: minimal | compact | standard | full (default compact).compact
Behavior5/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already show readOnlyHint, idempotentHint, etc. The description adds beyond them by specifying FTS relevance-ranked search, return fields, and the nomenclature-only constraint, giving full behavioral context without contradiction.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Three sentences, each earning its place: purpose, limitation, usage guidance. Front-loaded with key action and return format. No wasted words.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness5/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Despite no output schema, the description specifies return fields and structure. Covers search behavior, limitations, and usage context. With sibling list and robust annotations, no important context is missing.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, so baseline is 3. The description reiterates parameter roles (e.g., query is free-text) and adds a signature line, but does not significantly extend parameter meaning beyond the schema.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states 'Free-text search over gene symbols, names, aliases, and previous symbols' with a specific verb and resource. It distinguishes from siblings by directing to resolve_symbol for exact matches and highlighting nomenclature-only scope.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines5/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

Explicitly tells when to use this tool ('use this for partial names') and when to use alternatives ('use resolve_symbol for an exact symbol/id'). Also clarifies that descriptive queries only match nomenclature words, providing clear usage boundaries.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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