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Appendix MCP Server

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.

Installation

Claude Code

claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Claude Desktop / Claude Web Connectors

Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:

{
  "mcpServers": {
    "appendix": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

Other clients

Client

URL

Claude Code, Claude Desktop, Claude.ai connectors

https://mcp.appendix.com/mcp

Anthropic Messages API (mcp_servers)

https://mcp.appendix.com/mcp

The server speaks Streamable HTTP only — the current MCP spec transport (2025-03-26).

Related MCP server: Konsilium

Available Tools

Tool

Description

search_knowledge_base

Search medical literature and treatment guidelines

submit_encounter

Submit a clinical letter for physician review

list_conditions

List available conditions and medications

Development

npm install
npm run build
npm start

Watch mode:

npm run dev

Environment Variables

Variable

Default

Description

API_BASE_URL

https://api.appendix.com

Appendix API base URL

PORT

3001

HTTP listener port

Endpoints

Method

Path

Purpose

GET

/health

Health probe for the hosting platform

POST GET DELETE

/mcp

Streamable HTTP transport (stateless mode)

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