Skip to main content
Glama

get_acmg_genes

Retrieves the ACMG Secondary Findings v3.2 gene list of 73 medically actionable genes, including associated conditions and inheritance patterns. Use this to systematically review clinically actionable genetic results.

Instructions

Get the ACMG Secondary Findings v3.2 gene list — 73 genes recommended for clinical reporting. Returns gene name, associated condition, and inheritance pattern. Use this to systematically check all medically actionable genes.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault

No arguments

Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

No annotations are provided, so the description must cover behavioral aspects. It states the return fields but does not disclose whether the operation is read-only, requires authentication, or handles errors. The behavior is simple and partially transparent.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is two sentences long with no unnecessary words. It front-loads the core purpose and follows with a usage suggestion. Every sentence adds value.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

For a simple retrieval tool with no parameters and no output schema, the description adequately specifies the resource and return content. However, it does not mention whether the list is complete or paginated, which is a minor gap.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters4/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

There are no parameters, and schema coverage is 100%. The description does not need to add parameter semantics. Baseline for 0 parameters is 4.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly specifies the action ('Get'), the resource ('ACMG Secondary Findings v3.2 gene list'), the size ('73 genes'), and the return fields ('gene name, associated condition, and inheritance pattern'). It effectively distinguishes from sibling tools like get_all_pharmacogenomics.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines3/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description provides a useful context ('Use this to systematically check all medically actionable genes') but lacks explicit guidance on when not to use or alternatives. No comparison to sibling tools is given.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

Install Server

Other Tools

Latest Blog Posts

MCP directory API

We provide all the information about MCP servers via our MCP API.

curl -X GET 'https://glama.ai/api/mcp/v1/servers/HelixGenomics/Genomic-Agent-Discovery'

If you have feedback or need assistance with the MCP directory API, please join our Discord server