search_by_uniprot
Find ChEMBL targets using UniProt accession numbers to identify relevant biological targets in drug discovery research.
Instructions
Find ChEMBL targets by UniProt accession
Input Schema
TableJSON Schema
| Name | Required | Description | Default |
|---|---|---|---|
| uniprot_id | Yes | UniProt accession number | |
| limit | No | Number of results to return (1-1000, default: 25) |
Implementation Reference
- src/index.ts:1033-1059 (handler)The handler function for the 'search_by_uniprot' tool. It validates the uniprot_id argument, queries the ChEMBL target/search API with the UniProt ID, and returns the JSON response.
private async handleSearchByUniprot(args: any) { if (!args || typeof args.uniprot_id !== 'string') { throw new McpError(ErrorCode.InvalidParams, 'Invalid UniProt arguments'); } try { const response = await this.apiClient.get('/target/search.json', { params: { q: args.uniprot_id, limit: args.limit || 25, }, }); return { content: [ { type: 'text', text: JSON.stringify(response.data, null, 2), }, ], }; } catch (error) { throw new McpError( ErrorCode.InternalError, `Failed to search by UniProt: ${error instanceof Error ? error.message : 'Unknown error'}` ); } - src/index.ts:499-506 (schema)Input schema definition for the 'search_by_uniprot' tool, specifying uniprot_id as required string and optional limit.
inputSchema: { type: 'object', properties: { uniprot_id: { type: 'string', description: 'UniProt accession number' }, limit: { type: 'number', description: 'Number of results to return (1-1000, default: 25)', minimum: 1, maximum: 1000 }, }, required: ['uniprot_id'], }, - src/index.ts:496-507 (registration)Registration of the 'search_by_uniprot' tool in the ListTools response, including name, description, and input schema.
{ name: 'search_by_uniprot', description: 'Find ChEMBL targets by UniProt accession', inputSchema: { type: 'object', properties: { uniprot_id: { type: 'string', description: 'UniProt accession number' }, limit: { type: 'number', description: 'Number of results to return (1-1000, default: 25)', minimum: 1, maximum: 1000 }, }, required: ['uniprot_id'], }, }, - src/index.ts:762-763 (registration)Dispatch/registration in the CallToolRequestSchema switch statement that routes to the handler.
case 'search_by_uniprot': return await this.handleSearchByUniprot(args);