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search_compounds

Find chemical compounds in PubChem by name, CAS number, formula, or identifier to access detailed chemical information and properties.

Instructions

Search PubChem database for compounds by name, CAS number, formula, or identifier

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
queryYesSearch query (compound name, CAS, formula, or identifier)
search_typeNoType of search to perform (default: name)
max_recordsNoMaximum number of results (1-10000, default: 100)

Implementation Reference

  • The handler function that executes the search_compounds tool. Validates input, queries PubChem API for compound CIDs by various search types, fetches details for top results, and returns formatted JSON response.
    private async handleSearchCompounds(args: any) { if (!isValidCompoundSearchArgs(args)) { throw new McpError(ErrorCode.InvalidParams, 'Invalid compound search arguments'); } try { const searchType = args.search_type || 'name'; const maxRecords = args.max_records || 100; const response = await this.apiClient.get(`/compound/${searchType}/${encodeURIComponent(args.query)}/cids/JSON`, { params: { MaxRecords: maxRecords, }, }); if (response.data?.IdentifierList?.CID?.length > 0) { const cids = response.data.IdentifierList.CID.slice(0, 10); const detailsResponse = await this.apiClient.get(`/compound/cid/${cids.join(',')}/property/MolecularFormula,MolecularWeight,CanonicalSMILES,IUPACName/JSON`); return { content: [ { type: 'text', text: JSON.stringify({ query: args.query, search_type: searchType, total_found: response.data.IdentifierList.CID.length, details: detailsResponse.data, }, null, 2), }, ], }; } return { content: [ { type: 'text', text: JSON.stringify({ message: 'No compounds found', query: args.query }, null, 2), }, ], }; } catch (error) { throw new McpError( ErrorCode.InternalError, `Failed to search compounds: ${error instanceof Error ? error.message : 'Unknown error'}` ); } }
  • Input schema defining parameters for search_compounds: query (required string), search_type (enum), max_records (number 1-10000).
    inputSchema: { type: 'object', properties: { query: { type: 'string', description: 'Search query (compound name, CAS, formula, or identifier)' }, search_type: { type: 'string', enum: ['name', 'smiles', 'inchi', 'sdf', 'cid', 'formula'], description: 'Type of search to perform (default: name)' }, max_records: { type: 'number', description: 'Maximum number of results (1-10000, default: 100)', minimum: 1, maximum: 10000 }, }, required: ['query'], },
  • src/index.ts:370-382 (registration)
    Registration of search_compounds tool in the ListTools response, including name, description, and input schema.
    { name: 'search_compounds', description: 'Search PubChem database for compounds by name, CAS number, formula, or identifier', inputSchema: { type: 'object', properties: { query: { type: 'string', description: 'Search query (compound name, CAS, formula, or identifier)' }, search_type: { type: 'string', enum: ['name', 'smiles', 'inchi', 'sdf', 'cid', 'formula'], description: 'Type of search to perform (default: name)' }, max_records: { type: 'number', description: 'Maximum number of results (1-10000, default: 100)', minimum: 1, maximum: 10000 }, }, required: ['query'], }, },
  • src/index.ts:740-741 (registration)
    Dispatcher case in CallToolRequest handler that routes search_compounds calls to the handleSearchCompounds method.
    case 'search_compounds': return await this.handleSearchCompounds(args);
  • Type guard function for validating input arguments to search_compounds handler.
    const isValidCompoundSearchArgs = ( args: any ): args is { query: string; search_type?: string; max_records?: number } => { return ( typeof args === 'object' && args !== null && typeof args.query === 'string' && args.query.length > 0 && (args.search_type === undefined || ['name', 'smiles', 'inchi', 'sdf', 'cid', 'formula'].includes(args.search_type)) && (args.max_records === undefined || (typeof args.max_records === 'number' && args.max_records > 0 && args.max_records <= 10000)) ); };

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