ClinicalTrials.gov MCP Server

# Example: Retrieving Clinical Studies This example demonstrates how to use the `clinicaltrials_get_study` tool to fetch detailed information for clinical trials using their NCT IDs. ## Example 1: Single Study with Full Data ### Tool Call ```json { "nctIds": "NCT03372603", "summaryOnly": false } ``` ### Tool Response Returns the complete study data including: - Protocol sections (identification, status, description, conditions, interventions, design, eligibility, locations, outcomes) - Results section (if available) with participant flow, baseline characteristics, outcome measures, adverse events - Document section with protocol and analysis plan links - Derived sections with condition/intervention classifications Response size: ~200KB of detailed clinical trial data (truncated for brevity). --- ## Example 2: Single Study with Summary Only ### Tool Call ```json { "nctIds": "NCT03372603", "summaryOnly": true } ``` ### Tool Response ```json { "studies": [ { "nctId": "NCT03372603", "title": "A Placebo-controlled, Double-blind (Sponsor Open), Randomized, Crossover Study to Assess the Efficacy, Safety, and Tolerability of GSK2798745 in Participants With Chronic Cough", "briefSummary": "GSK2798745 is a potent and selective transient receptor potential vanilloid 4 (TRPV4) channel blocker being investigated for the treatment of chronic cough. This is a multi-center, randomized, placebo-controlled, double-blind, two-period crossover study with a purpose to evaluate efficacy and safety of GSK2798745. Each subject will have 2 treatment periods, and will be randomized to one of the following treatments in each period: A) Placebo matching to GSK2798745 once daily for 7 days. B) 4.8 milligrams (mg) GSK2798745 on Day 1, followed by 2.4 mg GSK2798745 once daily for 6 days. There will be a washout period of 14 to 21 days between the treatment periods. A maximum of 48 subjects will be enrolled in the study and the total duration of participation in the study will be maximum of 10 and a half weeks including follow-up visit.", "overallStatus": "TERMINATED", "conditions": ["Cough"], "interventions": [ { "name": "GSK2798745", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "leadSponsor": "GlaxoSmithKline" } ] } ``` --- ## Example 3: Multiple Studies ### Tool Call ```json { "nctIds": ["NCT03372603", "NCT04280783", "NCT05477043"], "summaryOnly": true } ``` ### Tool Response ```json { "studies": [ { "nctId": "NCT03372603", "title": "A Placebo-controlled, Double-blind (Sponsor Open), Randomized, Crossover Study to Assess the Efficacy, Safety, and Tolerability of GSK2798745 in Participants With Chronic Cough", "briefSummary": "GSK2798745 is a potent and selective transient receptor potential vanilloid 4 (TRPV4) channel blocker being investigated for the treatment of chronic cough...", "overallStatus": "TERMINATED", "conditions": ["Cough"], "interventions": [ { "name": "GSK2798745", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "leadSponsor": "GlaxoSmithKline" }, { "nctId": "NCT05477043", "title": "Ultrasound Evaluation of Ureteral Patency After Uterosacral Ligaments Suspension", "briefSummary": "Uterosacral ligament suspension (USLS) is a commonly performed procedure used to correct prolapse of the vaginal apex...", "overallStatus": "UNKNOWN", "conditions": [ "Uterovaginal Prolapse", "Ureteral Injury", "Surgery--Complications" ], "interventions": [ { "name": "Transabdominal ultrasound and cistoscopy", "type": "DIAGNOSTIC_TEST" } ], "leadSponsor": "University of Milano Bicocca" }, { "nctId": "NCT04280783", "title": "Feasibility and Acceptability of a Web-based Physical Activity for the Heart (PATH) Intervention Designed to Reduce the Risk of Heart Disease Among Inactive African Americans", "briefSummary": "Barriers to physical activity (PA) among African Americans (AAs) have been extensively studied...", "overallStatus": "COMPLETED", "conditions": [ "Cardiovascular Risk Factor", "Prediabetes", "Overweight and Obesity", "Sedentary Behavior" ], "interventions": [ { "name": "The Physical Activity for The Heart (PATH) intervention", "type": "BEHAVIORAL" }, { "name": "Be Active Your Way Booklet", "type": "BEHAVIORAL" } ], "leadSponsor": "University of Pittsburgh" } ] } ``` --- ## Example 4: Invalid NCT ID ### Tool Call ```json { "nctIds": "NCT99999999", "summaryOnly": true } ``` ### Tool Response ``` Error: Failed to fetch any studies. Errors: NCT99999999: Fetch failed for https://clinicaltrials.gov/api/v2/studies/NCT99999999. Status: 404 ``` ## Notes - The `summaryOnly` parameter defaults to `false` (returns full data) - You can request up to 5 studies at once by providing an array of NCT IDs - NCT IDs must match the format: NCT followed by 8 digits (case-insensitive) - Invalid or non-existent NCT IDs will return error messages - Full data responses can be very large (100-200KB per study)