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WormBase MCP Server

MCP server for querying WormBase - the C. elegans and nematode genomics database.

Installation

Claude Desktop

Add to ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows):

{ "mcpServers": { "wormbase": { "command": "npx", "args": ["-y", "@nuin/wormbase-mcp"] } } }

Claude Code (CLI)

Add to ~/.claude/settings.json:

{ "mcpServers": { "wormbase": { "command": "npx", "args": ["-y", "@nuin/wormbase-mcp"] } } }

Cursor

Add to Cursor settings (Settings > MCP Servers):

{ "wormbase": { "command": "npx", "args": ["-y", "@nuin/wormbase-mcp"] } }

Windsurf

Add to ~/.codeium/windsurf/mcp_config.json:

{ "mcpServers": { "wormbase": { "command": "npx", "args": ["-y", "@nuin/wormbase-mcp"] } } }

From source

git clone https://github.com/WormBase/wormbase-mcp.git cd wormbase-mcp npm install && npm run build

Then use the local path in your config:

{ "mcpServers": { "wormbase": { "command": "node", "args": ["/path/to/wormbase-mcp/dist/index.js"] } } }

Usage

Just ask questions naturally:

  • "What does daf-2 do?"

  • "Search for genes involved in longevity"

  • "Get phenotypes for unc-13"

  • "Find interactions for lin-14"

  • "What are the homologs of aap-1?"

  • "Give me the sequence of protein CE29083"

Tools

Tool

Description

search

Search genes, proteins, phenotypes, strains

get_gene

Gene details (accepts names like

daf-2

or IDs like

WBGene00000898

)

get_protein

Protein sequences and domains

get_phenotype

Phenotype info and associated genes

get_disease

Human disease models

get_strain

Laboratory strains

get_variation

Alleles and mutations

get_interactions

Genetic and physical interactions

get_expression

Expression patterns

get_ontology

GO annotations

get_paper

Publication details

Data Sources

License

MIT

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