WormBase MCP Server
MCP server for querying WormBase - the C. elegans and nematode genomics database.
Installation
Claude Desktop
Add to ~/Library/Application Support/Claude/claude_desktop_config.json (macOS) or %APPDATA%\Claude\claude_desktop_config.json (Windows):
Claude Code (CLI)
Add to ~/.claude/settings.json:
Cursor
Add to Cursor settings (Settings > MCP Servers):
Windsurf
Add to ~/.codeium/windsurf/mcp_config.json:
From source
Then use the local path in your config:
Usage
Just ask questions naturally:
"What does daf-2 do?"
"Search for genes involved in longevity"
"Get phenotypes for unc-13"
"Find interactions for lin-14"
"What are the homologs of aap-1?"
"Give me the sequence of protein CE29083"
Tools
Tool | Description |
| Search genes, proteins, phenotypes, strains |
| Gene details (accepts names like
or IDs like
) |
| Protein sequences and domains |
| Phenotype info and associated genes |
| Human disease models |
| Laboratory strains |
| Alleles and mutations |
| Genetic and physical interactions |
| Expression patterns |
| GO annotations |
| Publication details |
Data Sources
Search & name resolution: WormMine
Detailed data: WormBase REST API
License
MIT