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Opentargets

by io.github.pipeworx-io
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Drug

drug
Read-onlyIdempotent

"Drug info for [ChEMBL ID]" / "look up [drug] target info" / "[CHEMBL...] mechanism" — fetch a drug profile from Open Targets by ChEMBL ID. Returns name, mechanisms of action, indications, target genes, trade names, clinical-trial phase. Use for drug research, mechanism queries.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
chembl_idYese.g. "CHEMBL1201583" (imatinib)

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
drugNo

Schema Changelog

Changes observed during successful MCP inspections.

  1. Changed2 schema fields changed
    • removedOutput schema / properties / data
      Removed value: -{
-  "properties": {
-    "drug": {
-      "properties": {
-        "drugType": {
-          "description": "Drug type",
-          "type": "string"
-        },
-        "id": {
-          "description": "ChEMBL drug ID",
-          "type": "string"
-        },
-        "indications": {
-          "properties": {
-            "rows": {
-              "items": {
-                "properties": {
-                  "disease": {
-                    "properties": {
-                      "id": {
-                        "description": "Disease ID",
-                        "type": "string"
-                      },
-                      "name": {
-                        "description": "Disease name",
-                        "type": "string"
-                      }
-                    },
-                    "type": "object"
-                  },
-                  "maxPhaseForIndication": {
-                    "description": "Max phase for indication",
-                    "type": "integer"
-                  }
-                },
-                "type": "object"
-              },
-              "type": "array"
-            }
-          },
-          "type": "object"
-        },
-        "maximumClinicalTrialPhase": {
-          "description": "Max clinical trial phase",
-          "type": "integer"
-        },
-        "mechanismsOfAction": {
-          "properties": {
-            "rows": {
-              "items": {
-                "properties": {
-                  "actionType": {
-                    "description": "Mechanism action type",
-                    "type": "string"
-                  },
-                  "mechanismOfAction": {
-                    "description": "Mechanism description",
-                    "type": "string"
-                  },
-                  "targets": {
-                    "items": {
-                      "properties": {
-                        "approvedSymbol": {
-                          "description": "Target symbol",
-                          "type": "string"
-                        },
-                        "id": {
-                          "description": "Target ID",
-                          "type": "string"
-                        }
-                      },
-                      "type": "object"
-                    },
-                    "type": "array"
-                  }
-                },
-                "type": "object"
-              },
-              "type": "array"
-            }
-          },
-          "type": "object"
-        },
-        "name": {
-          "description": "Drug name",
-          "type": "string"
-        },
-        "tradeNames": {
-          "items": {
-            "description": "Trade name",
-            "type": "string"
-          },
-          "type": "array"
-        }
-      },
-      "type": "object"
-    }
-  },
-  "type": "object"
-}
    • addedOutput schema / properties / drug
      Added value: +{
+  "properties": {
+    "drugType": {
+      "type": "string"
+    },
+    "id": {
+      "type": "string"
+    },
+    "indications": {
+      "properties": {
+        "rows": {
+          "items": {
+            "properties": {
+              "disease": {
+                "properties": {
+                  "id": {
+                    "type": "string"
+                  },
+                  "name": {
+                    "type": "string"
+                  }
+                },
+                "type": "object"
+              },
+              "maxClinicalStage": {
+                "type": "string"
+              }
+            },
+            "type": "object"
+          },
+          "type": "array"
+        }
+      },
+      "type": "object"
+    },
+    "maximumClinicalStage": {
+      "type": "string"
+    },
+    "mechanismsOfAction": {
+      "properties": {
+        "rows": {
+          "items": {
+            "properties": {
+              "actionType": {
+                "type": "string"
+              },
+              "mechanismOfAction": {
+                "type": "string"
+              },
+              "targets": {
+                "items": {
+                  "properties": {
+                    "approvedSymbol": {
+                      "type": "string"
+                    },
+                    "id": {
+                      "type": "string"
+                    }
+                  },
+                  "type": "object"
+                },
+                "type": "array"
+              }
+            },
+            "type": "object"
+          },
+          "type": "array"
+        }
+      },
+      "type": "object"
+    },
+    "name": {
+      "type": "string"
+    },
+    "tradeNames": {
+      "items": {
+        "properties": {
+          "label": {
+            "type": "string"
+          },
+          "source": {
+            "type": "string"
+          }
+        },
+        "type": "object"
+      },
+      "type": "array"
+    }
+  },
+  "type": "object"
+}
  2. Changed2 schema fields changed
    • addedInput schema / examples
      Added value: +[
+  {
+    "chembl_id": "CHEMBL1201583"
+  },
+  {
+    "chembl_id": "CHEMBL25"
+  }
+]
    • changedOutput schema / (root)
      Previous value: -nullNew value: +{
+  "properties": {
+    "data": {
+      "properties": {
+        "drug": {
+          "properties": {
+            "drugType": {
+              "description": "Drug type",
+              "type": "string"
+            },
+            "id": {
+              "description": "ChEMBL drug ID",
+              "type": "string"
+            },
+            "indications": {
+              "properties": {
+                "rows": {
+                  "items": {
+                    "properties": {
+                      "disease": {
+                        "properties": {
+                          "id": {
+                            "description": "Disease ID",
+                            "type": "string"
+                          },
+                          "name": {
+                            "description": "Disease name",
+                            "type": "string"
+                          }
+                        },
+                        "type": "object"
+                      },
+                      "maxPhaseForIndication": {
+                        "description": "Max phase for indication",
+                        "type": "integer"
+                      }
+                    },
+                    "type": "object"
+                  },
+                  "type": "array"
+                }
+              },
+              "type": "object"
+            },
+            "maximumClinicalTrialPhase": {
+              "description": "Max clinical trial phase",
+              "type": "integer"
+            },
+            "mechanismsOfAction": {
+              "properties": {
+                "rows": {
+                  "items": {
+                    "properties": {
+                      "actionType": {
+                        "description": "Mechanism action type",
+                        "type": "string"
+                      },
+                      "mechanismOfAction": {
+                        "description": "Mechanism description",
+                        "type": "string"
+                      },
+                      "targets": {
+                        "items": {
+                          "properties": {
+                            "approvedSymbol": {
+                              "description": "Target symbol",
+                              "type": "string"
+                            },
+                            "id": {
+                              "description": "Target ID",
+                              "type": "string"
+                            }
+                          },
+                          "type": "object"
+                        },
+                        "type": "array"
+                      }
+                    },
+                    "type": "object"
+                  },
+                  "type": "array"
+                }
+              },
+              "type": "object"
+            },
+            "name": {
+              "description": "Drug name",
+              "type": "string"
+            },
+            "tradeNames": {
+              "items": {
+                "description": "Trade name",
+                "type": "string"
+              },
+              "type": "array"
+            }
+          },
+          "type": "object"
+        }
+      },
+      "type": "object"
+    }
+  },
+  "type": "object"
+}
  3. First observed

TDQS

Score is being calculated.

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