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"Free and open-source coding assistants" matching MCP servers:

  • open-dental-mcp

    sanjibani
    A
    license
    A
    quality
    B
    maintenance
    Enables interaction with Open Dental practice management software, allowing reading of patients, appointments, providers, procedures, and recalls, as well as writing communications back to patient charts via MCP clients.
    14
    4
    MIT
  • Open Targets Platform MCP by opentargets

    Open Targets Platform MCPofficial

    opentargets
    A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI assistants to interact with the Open Targets Platform API to search and retrieve comprehensive data about target-disease associations, drugs, genes, and drug discovery information through GraphQL queries.
    37
    Apache 2.0
  • openpgx by open-pgx

    openpgxofficial

    open-pgx
    A
    license
    A
    quality
    D
    maintenance
    Enables AI-driven pharmacogenomic analysis by querying structured genetic variant, drug response, and disease risk data. Supports natural language questions about medications, traits, and health risks based on user genome data, with privacy-first local execution.
    16
    455
    11
    MIT

  • live-ketcher-mcp

    MALeitch
    A
    license
    Not graded
    quality
    B
    maintenance
    MCP server that connects AI assistants to a live Ketcher window, the open-source web-based chemical structure editor. Draw, edit, and organize structures directly in the canvas you have open.
    MIT

  • TransBench

    kayomarz97
    F
    license
    A
    quality
    B
    maintenance
    TransBench is a translational research agent that takes free-text clinical observations, decomposes them into biological axes, generates falsifiable hypotheses grounded in PubMed evidence, and designs reproducible computational experiments with concrete datasets for Claude Science.
    3

  • reactome-mcp

    tc2fh
    A
    license
    A
    quality
    C
    maintenance
    Enables coding agents to interact with the Reactome pathway database, including search, lookup, hierarchy traversal, SBML/SBGN export, and gene-set enrichment analysis.
    17
    MIT

  • medrxiv-mcp

    yogsoth-ai
    A
    license
    A
    quality
    C
    maintenance
    MCP server that turns a medRxiv DOI into clean markdown full text and provides free, relevance-ranked preprint search via Europe PMC.
    2
    1
    Apache 2.0

  • openi

    LeviReisJs
    A
    license
    A
    quality
    B
    maintenance
    Enables searching biomedical images (X-rays, CT/MRI, clinical photos, etc.) from the Open-i database using natural language queries, returning image results as Markdown links.
    2
    MIT

  • searchloinc

    jesse-smith
    A
    license
    A
    quality
    B
    maintenance
    Enables LLMs to search LOINC terms with free-text, relevance-ranked, and faceted queries via the LOINC Search API, mirroring the loinc.org/search experience.
    5
    MIT

  • Rosetta MCP Server

    Arielbs
    A
    license
    A
    quality
    F
    maintenance
    An MCP server that enables AI coding assistants to interact with Rosetta, PyRosetta, and Biotite for running RosettaScripts, validating XML, translating between Rosetta and Biotite, scoring structures, and querying documentation.
    19
    112
    18
    MIT

  • FHIR MCP Server

    brianbastian01
    A
    license
    A
    quality
    C
    maintenance
    Provides safe read-only access to synthetic healthcare data via FHIR R4, enabling AI assistants to search patients, retrieve vitals, and summarize conditions using a public sandbox.
    4
    90
    MIT

  • plant-genomics-mcp

    musharna
    A
    license
    A
    quality
    A
    maintenance
    ▎ Provides 32 tools for plant-genomics locus lookup across 11 free public backends (Ensembl Plants, Phytozome, UniProtKB, Europe PMC, QuickGO, NCBI BLAST, Gramene, KEGG, STRING-DB, ATTED-II, BAR). Takes a TAIR-style locus plus optional organism and returns gene metadata, functional/pathway annotation, interactions, co-expression, and literature — in single-locus, batch, and cross-source synthesis.
    50
    3
    MIT

  • digeguigui

    Gaoshan0971
    A
    license
    A
    quality
    C
    maintenance
    Global reptile & exotic pet knowledge base. 633 species, AI identification, genetics calculator, 12-dimension care, health diagnosis, pricing, provenance. Free 9 tools, 10 req/min.
    9
    1
    MIT