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  • A
    license
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    quality
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    maintenance
    Enables AI assistants to query VCF files through MCP tools that summarize variants, identify pathogenic and carrier variants, interpret pharmacogenomic results, and determine APOE status, with web app and Claude Desktop support.
    MIT
  • A
    license
    A
    quality
    B
    maintenance
    Enables AI agents to retrieve cited pharmacogenomic and gene-variant information, including drug–gene guidance from CPIC/DPWG and rsID lookups, so responses can quote curated sources instead of relying on memory. A local package also lets users read raw DNA files on their own computer without sending the file data to the remote service.
    2
    43 PyPI
    MIT
  • A
    license
    A
    quality
    C
    maintenance
    Enables querying the EMBL-EBI catalog of published polygenic scores through read-only tools that search scores, traits, publications, performance metrics, sample sets, cohorts, and releases, and that trace GWAS studies and resolve ontology and ancestry identifiers. It also lists and downloads the associated scoring-file and metadata files from the catalog's FTP site.
    24
    1
    Apache 2.0
  • A
    license
    A
    quality
    C
    maintenance
    Enables AI assistants to query the eggNOG 7 database in natural language for protein lookups, orthologous groups, pairwise orthologs, protein families, taxonomy, and database statistics. Also delivers structured functional annotations such as KEGG KO and GO terms with confidence scores, plus an index of bulk-downloadable data files.
    10
    1
    MIT
  • A
    license
    A
    quality
    C
    maintenance
    Enables LLM-powered applications to look up bacterial and archaeal taxonomy, search genomes, browse and navigate the taxonomic tree, and compare genomes or find phylogenetic paths between taxa. It works out of the box with a built-in reference dataset covering major phyla and can be pointed at full Genome Taxonomy Database TSV files for comprehensive queries.
    12
    1
    MIT
  • A
    license
    A
    quality
    A
    maintenance
    Enables users to resolve regulatory entities, query and analyze biological interactions, inspect evidence, export reproducible network data, and download official compressed source files on demand through an online-first, read-only service.
    9
    MIT
  • A
    license
    A
    quality
    A
    maintenance
    Reads raw lab-instrument files (microscopy, mass spectrometry, chromatography, flow cytometry, NMR, electrophysiology, spectroscopy, plate readers, qPCR) without vendor software, returning metadata, images, spectra and traces as JSON. It also checks files for damage, runs common analyses, and exports to open formats such as OME-TIFF, OME-Zarr, mzML, Parquet and NWB.
    28
    138 PyPI
    10
    Apache 2.0
  • A
    license
    A
    quality
    C
    maintenance
    An MCP server that lets AI agents record each executed analysis step with SHA-256 hashes of inputs and outputs, validate bioinformatics file formats (FASTA, FASTQ, VCF, BED, GFF/GTF, CSV, TSV, JSON), verify recorded files still match their hashes, replay commands to confirm identical outputs, and generate provenance reports of stored runs.
    6
    MIT
  • A
    license
    B
    quality
    A
    maintenance
    Retrieve genomic data from EGA, ENA, ENCODE, GEO and NCBI, read bounded regions from indexed BAM/CRAM, VCF and bigWig files, and query source-attributed reference evidence. Runs locally with 23 MCP tools. MIT-licensed; research use.
    23
    23 PyPI
    3
    MIT
  • F
    license
    B
    quality
    D
    maintenance
    Enables users to generate volcano plots by submitting jobs with input files and parameters, supporting local or Docker execution.
    8
    1
    -
  • A
    license
    Not graded
    quality
    A
    maintenance
    Enables MCP clients and the cheminfo chat to call one catalog of tools while carrying produced structures, reaction schemes, spectra and files beside the answer rather than through the model. It provides tool listing, tool invocation, and stateless Streamable HTTP MCP endpoints.
    880 npm
    MIT
  • A
    license
    Not graded
    quality
    D
    maintenance
    Enables AI assistants to perform quality control analysis on high-throughput sequencing data using FastQC and MultiQC. It supports single-file and batch processing of FASTQ/FASTA files and generates comprehensive, interactive summary reports.
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables searching and retrieving cancer-genomics projects, cases, and genomic data files — including TCGA, TARGET, and CPTAC — via keyless, open-access metadata tools. Supports filtering by primary site, project, or data category, and can route plain-English questions to the right tool automatically.
    194 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables searching and retrieving curated mathematical models of biological systems from BioModels, including metadata, source publications, and downloadable model files in SBML, BioPAX, and other formats, with querying by pathway, disease, organism, gene, or author.
    427 npm
    MIT
  • F
    license
    Not graded
    quality
    Not graded
    maintenance
    Enables interaction with the RCSB Protein Data Bank to search, analyze, and visualize protein structures. It provides specialized tools for downloading coordinate files and performing structural modifications like residue mutations and metal atom replacements.
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  • F
    license
    Not graded
    quality
    D
    maintenance
    Enables protein sequence analysis and structure prediction by extracting ESM-2 embeddings and batch processing FASTA files via Docker. It provides tools for large-scale embedding extraction, job monitoring, and model management within an MCP-compatible environment.
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