MCP-Grounded
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Wait a few minutes for the server to deploy. Once ready, it will show a "Started" state.
In the chat, type
@followed by the MCP server name and your instructions, e.g., "@MCP-Groundedclassify this skin lesion image, abstain if uncertain"
That's it! The server will respond to your query, and you can continue using it as needed.
Here is a step-by-step guide with screenshots.
MCP-Grounded π©Ί
A multi-agent pipeline for medical image classification with verification-aware abstention, coordinated via the Model Context Protocol (MCP).
"Instead of always guessing, the AI says β I'm not confident enough, I'll skip this one."
What is this?
MCP-Grounded is a 4-agent AI pipeline that classifies skin lesion images from the HAM10000 dataset. What makes it novel: the final agent can abstain from answering when it isn't confident β making it safer for medical use.
All four agents are real MCP tools, not just described as such.
Related MCP server: Prior Authorization System MCP Server
Pipeline
Skin lesion image
β
βΌ
βββββββββββββββββββ
β BiomedCLIP β Agent 1: Extract 512-dim embedding
β (Extract) β
ββββββββββ¬βββββββββ
β
βΌ βββββββββββββββββββββββββββββββββββββββββββ
β MCP Server β
β β
β ββββββββββββ ββββββββββββ β
β β Retrieve ββββββββΆβ Rerank β β
β β Agent 2 β β Agent 3 β β
β ββββββββββββ ββββββ¬ββββββ β
β β β
β ββββββββββΌβββββββββββ β
β β Verify / Abstain β β
β β Agent 4 β β
β ββββββββββ¬ββββββββββββ β
βββββββββββββββββββββββββββ β ββββββββββββββ
β
βββββββββββββββ΄ββββββββββββββ
β β
conf β₯ Ο conf < Ο
β β
PREDICT ABSTAINResults
Retrieval Quality
Metric | Value |
Recall@1 | 77.9% |
Recall@5 | 93.5% |
Recall@10 | 96.3% |
Recall@50 | 99.2% |
Verification-Aware Abstention (key result)
Threshold Ο | Coverage | Selective Accuracy |
0.0 (answer all) | 100.0% | 67.0% |
0.5 | 96.9% | 69.0% |
0.6 | 83.4% | 77.0% |
0.7 | 52.0% | 91.3% |
0.8 | 4.9% | 98.6% |
At Ο = 0.7, selective accuracy improves +24 percentage points over the no-abstention baseline.
RiskβCoverage Curve

As the confidence threshold rises, coverage drops but selective accuracy climbs sharply β proving abstention makes the system safer.
Calibration
Metric | Value |
ECE before temperature scaling | 0.191 |
ECE after temperature scaling | 0.185 |
Learned temperature T | 0.944 |
Dataset
HAM10000 β 10,015 dermoscopic images across 7 skin lesion categories:
akiec Β· bcc Β· bkl Β· df Β· mel Β· nv Β· vasc
Split: 70% train / 15% validation / 15% test (stratified).
How to Run
Step 1 β Generate embeddings (Google Colab, GPU)
Open notebook1_embeddings.py in Google Colab with a T4 GPU runtime. Run all cells top to bottom. Downloads HAM10000 and produces embeddings.npz.
Step 2 β Run experiments (Google Colab)
Open notebook2_experiments.py in a new Colab notebook. Upload embeddings.npz. Run all cells. Produces:
All result tables (Recall@K, accuracy, calibration, abstention)
risk_coverage.pngclf_weights.npz
Step 3 β Run the MCP server (local)
pip install "mcp[cli]" numpy torch
python mcp_grounded_server.pyStarts a live MCP server with three callable tools: retrieve, rerank, classify_and_verify.
Requirements
mcp[cli]
numpy
torch
open_clip_torch
scikit-learn
pandas
pillow
tqdm
matplotlibSee requirements.txt.
File Structure
mcp_grounded/
βββ notebook1_embeddings.py # Colab: download HAM10000, extract BiomedCLIP embeddings
βββ notebook2_experiments.py # Colab: retrieval, calibration, abstention experiments
βββ mcp_grounded_server.py # Local: FastMCP server exposing 4 agents as tools
βββ risk_coverage.png # Figure 2: risk-coverage curve
βββ requirements.txt
βββ README.mdCitation
If you use this work, please cite:
@inproceedings{mcpgrounded2025,
title = {MCP-Grounded: A Multi-Agent Pipeline with Verification-Aware Abstention for Medical Image Classification},
author = {[Your Name]},
booktitle = {[Conference Name]},
year = {2025}
}License
MIT License. Dataset (HAM10000) is CC-BY-NC-SA-4.0 β see Kaggle for terms.
Built with BiomedCLIP Β· FastMCP Β· HAM10000
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