openevidence-mcp
Allows GitHub Copilot environments with MCP support to use OpenEvidence tools for researching medical evidence, including checking authentication, listing article history, fetching articles, and asking research questions.
Allows OpenAI Codex agents to use OpenEvidence tools for researching medical evidence, including checking authentication, listing article history, fetching articles, and asking research questions.
Allows Replit environments with MCP support to use OpenEvidence tools for researching medical evidence, including checking authentication, listing article history, fetching articles, and asking research questions.
Click on "Install Server".
Wait a few minutes for the server to deploy. Once ready, it will show a "Started" state.
In the chat, type
@followed by the MCP server name and your instructions, e.g., "@openevidence-mcpask about the efficacy of mRNA vaccines against Omicron"
That's it! The server will respond to your query, and you can continue using it as needed.
Here is a step-by-step guide with screenshots.
OpenEvidence MCP (Unofficial)
OpenEvidence MCP is an unofficial Model Context Protocol server that connects OpenEvidence to Codex, Claude Code, Claude Desktop, Cursor, Cline, Continue, and other MCP-compatible clients through your own authenticated browser session.
This project is unofficial and is not affiliated with OpenEvidence. It does not provide medical advice, does not bypass access controls, and should only be used with your own OpenEvidence account in compliance with applicable terms, privacy rules, and clinical governance requirements.
Translations: Русский | Español | 简体中文 | 繁體中文(台灣) | 한국어 | हिन्दी
Agent Onboarding & Installation
Using Codex, Claude Code, Cursor, or another local AI coding agent? You can let the agent handle the entire setup, compilation, and local MCP configuration for you!
Copy and paste this short bootstrap prompt directly into your local AI coding assistant:
Please install OpenEvidence MCP for me: clone https://github.com/bakhtiersizhaev/openevidence-mcp, install dependencies, run build, auto-configure this MCP server in my local client (Claude Desktop/Codex/Cursor), guide me through the one-time Edge/Chrome login using `npm run login:session`, and run `npm run smoke` to verify. Keep everything strictly local and secure.For the comprehensive, step-by-step setup playbook and rules, see docs/AGENT_INSTALL_PROMPT.md.
Related MCP server: cdp-bridge
What it does
OpenEvidence MCP runs a local stdio MCP server that lets MCP clients use your existing OpenEvidence browser session for:
checking whether the saved session is authenticated;
listing your OpenEvidence question/article history;
fetching a full article payload by ID;
asking an OpenEvidence research question and optionally waiting for completion;
polling an existing OpenEvidence article until it completes.
No official OpenEvidence API token is required.
What it does NOT do
It is not affiliated with, endorsed by, or approved by OpenEvidence.
It does not provide medical advice or replace clinical judgment.
It does not bypass authentication, paywalls, or access controls.
It does not collect credentials.
It does not send your browser session state anywhere except to OpenEvidence through local requests from your machine.
It should not be used for patient-specific diagnosis or treatment decisions without appropriate human review.
Who it is for
clinicians using their own OpenEvidence account;
medical researchers;
AI operators building evidence-research workflows;
MCP developers integrating local tools with Codex, Claude, Cursor, Cline, Continue, or similar clients.
Tested / Target Clients
This project is designed for MCP-compatible clients and local agent workflows. Only Codex and Claude-style local configuration examples are maintained in this repository unless otherwise noted.
Client | Status | Notes |
OpenAI Codex / Codex CLI / Codex app | Target | Recommended local MCP workflow. |
Claude Code | Target | Recommended agent workflow. |
Claude Desktop / Claude app with MCP support | Target | Local MCP server configuration. |
Cursor | Compatible | MCP-compatible IDE workflow. |
Cline | Compatible | VS Code agent workflow. |
Continue | Compatible | Open-source IDE assistant workflow. |
VS Code / GitHub Copilot environments with MCP support | Experimental | Depends on local MCP support and client configuration. |
Windsurf / Zed / Replit / Sourcegraph-style MCP hosts | Experimental | Not guaranteed unless tested. |
Gemini CLI / Google Antigravity-style agent environments | Experimental | Watchlist/ecosystem target, not a maintained example. |
Other MCP-compatible hosts may work as well, but the examples in this repository focus on Codex and Claude-style local MCP configuration.
Features
Tool | Purpose | Auth required | Side effects |
| Checks whether the saved OpenEvidence browser session is authenticated. | Yes, local browser profile must be logged in. | None. |
| Lists prior OpenEvidence articles with optional pagination and search. Returns a privacy-reduced list unless | Yes. | None. |
| Fetches an article by ID and returns normalized fields ( | Yes. | None. |
| Waits for an existing article ID to complete; useful after non-blocking | Yes. | None. |
| Creates an OpenEvidence research question and optionally waits for the article to complete. | Yes. | Creates a question/article in your OpenEvidence account. |
Agent Tool-Calling Notes
The MCP server includes built-in instructions and a prompt named openevidence_research_workflow for clients that expose MCP prompts.
Recommended agent workflow:
Call
oe_auth_statuswhen auth state is unknown.Use
oe_history_listonly when the user wants prior OpenEvidence work or an article ID.Use
oe_article_getwhen you already have an article ID.For long research questions, call
oe_askwithwait_for_completion=false, then calloe_article_waitwith the returnedarticle_id.Use
original_article_idonly for true follow-up continuity. Omit it for fresh questions to avoid stale thread context.Treat outputs as evidence-research context, not medical advice, diagnosis, or clinical orders.
Related commands:
Command | Purpose |
| Recommended one-time login. Opens Chrome/Edge with the local OpenEvidence MCP profile. |
| Legacy/development Playwright login flow that also uses the local profile. |
| Legacy system-browser login/export flow for debugging Google SSO issues. |
| Verifies auth and basic OpenEvidence connectivity. |
Requirements
Node.js 20+
npm 10+
OpenEvidence account
macOS, Windows, or Linux
Chromium installed by Playwright (
npx playwright install chromium)
Availability Note
OpenEvidence availability may depend on region, account eligibility, and OpenEvidence policy. Public materials in May 2026 indicate verified U.S. HCP/NPI-centered access and EU/U.K. unavailability; this project does not bypass those restrictions.
Useful references:
Quick Start
macOS
git clone https://github.com/bakhtiersizhaev/openevidence-mcp.git
cd openevidence-mcp
./scripts/setup-macos.sh
npm run login:session
npm run smokeUbuntu/Linux
git clone https://github.com/bakhtiersizhaev/openevidence-mcp.git
cd openevidence-mcp
./scripts/setup-ubuntu.sh
npm run login:session
npm run smokeWindows PowerShell
git clone https://github.com/bakhtiersizhaev/openevidence-mcp.git
cd openevidence-mcp
.\scripts\setup-windows.ps1
npm run login:session
npm run smokeLogin Flow
Recommended one-time login:
npm run login:sessionThe command opens Chrome or Edge with a local OpenEvidence MCP browser profile. Sign in to OpenEvidence with your own account, confirm the normal OpenEvidence page loads, close that browser window, return to the terminal, and press Enter.
Default local profile path:
macOS/Linux:
~/.openevidence-mcp/browser-profileWindows:
%USERPROFILE%\.openevidence-mcp\browser-profile
The MCP server reuses this same local profile during its process lifetime. It may start a minimized local browser process for OpenEvidence calls, but it does not install an extension, expose a public network service, export cookies, or ask for your password.
Legacy/development flow:
npm run loginIf Google sign-in says the browser or app may not be secure during the legacy flow, use the session login instead:
npm run login:sessionDo not share browser profile files, storage-state files, cookies, screenshots with private account data, or patient-identifiable information.
MCP Client Setup
Build before registering the server:
npm run buildAutomatic Setup (Recommended)
You can automatically register the OpenEvidence MCP server with your favorite client using the built-in installer:
Claude Desktop (
claude-app):npx openevidence-mcp install --client claude-app # or via npm shortcut: npm run install:claude-appCodex Desktop (
codex-app):npx openevidence-mcp install --client codex-app # or via npm shortcut: npm run install:codex-appClaude Code (
claude-code):npx openevidence-mcp install --client claude-code # or via npm shortcut: npm run install:claude-codeCodex CLI (
codex-cli):npx openevidence-mcp install --client codex-cli # or via npm shortcut: npm run install:codex-cliGoogle Antigravity (
antigravity):npx openevidence-mcp install --client antigravity # or via npm shortcut: npm run install:antigravityCursor (
cursor):npx openevidence-mcp install --client cursor # or via npm shortcut: npm run install:cursorWindsurf (
windsurf):npx openevidence-mcp install --client windsurf # or via npm shortcut: npm run install:windsurf
To uninstall, you can run:
npx openevidence-mcp uninstall --client <client-id>Manual Setup
Codex
Add this to ~/.codex/config.toml:
[mcp_servers.openevidence]
command = "node"
args = ["/ABSOLUTE/PATH/openevidence-mcp/dist/server.js"]
startup_timeout_sec = 60Windows example:
[mcp_servers.openevidence]
command = "node"
args = ["C:\\Users\\<user>\\openevidence-mcp\\dist\\server.js"]
startup_timeout_sec = 60Claude Desktop
Add this to claude_desktop_config.json:
{
"mcpServers": {
"openevidence": {
"command": "node",
"args": ["/ABSOLUTE/PATH/openevidence-mcp/dist/server.js"]
}
}
}Cursor, Cline, Continue
Use the same stdio server shape if your client supports MCP server command/args configuration:
{
"command": "node",
"args": ["/ABSOLUTE/PATH/openevidence-mcp/dist/server.js"]
}Example configs are in examples/.
Verify
npm run smokeExpected result with a valid session:
ok: trueauthenticated: truea redacted history preview
If smoke fails with an auth error, run npm run login:session again. Smoke requires a real OpenEvidence account session and will not pass in a clean CI environment unless a local session profile is available.
By default, smoke output redacts account and history content. Use npm run smoke -- --verbose only in a private terminal if raw account/history payloads are needed for debugging.
Developer checks:
npm test
npm run build
npm run checkSecurity Notes
Treat browser profiles,
storage-state.json, and cookies as secrets.Do not commit
.env, session state, screenshots with account data, or patient-identifiable information.Use only your own OpenEvidence account.
Keep MCP client configs pointed at the built local server path you control.
Review tool calls from autonomous agents before using outputs in clinical or operational workflows.
See
SECURITY.mdfor vulnerability reporting and supported scope.
Troubleshooting
See docs/TROUBLESHOOTING.md for detailed recovery steps.
Common fixes:
authenticated: false: rerunnpm run login:session.Google says browser is not secure in the legacy login flow: run
npm run login:session.Browser install errors: run
npx playwright install chromium.MCP client cannot start server: confirm
npm run buildsucceeded and use an absolute path todist/server.js.Windows path issues: escape backslashes in JSON/TOML or use full absolute paths.
Node errors: confirm
node --versionis 20 or newer.OpenEvidence UI/API changed: open an issue with sanitized logs and no private account or patient data.
oe_askcannot find the question input or submit button: OpenEvidence UI may have changed; open an issue with sanitized logs and no private account or patient data.
Roadmap
Keep tool descriptions compact and agent-friendly.
Add focused tests around config and response parsing.
Improve smoke diagnostics without exposing session details.
Track MCP client setup examples as client configuration formats evolve.
License & Attribution
Apache-2.0 (LICENSE) + NOTICE.
If you redistribute, fork, or build derivative versions, keep attribution to:
Original author: Bakhtier Sizhaev
Original repository:
https://github.com/bakhtiersizhaev/openevidence-mcp
Suggested attribution line:
Based on OpenEvidence MCP by Bakhtier Sizhaev - https://github.com/bakhtiersizhaev/openevidence-mcpStar History
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