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GenPark Bio-Agent

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🧬 GenPark Bio-Agent

GenPark Official LinkedIn MCP Compliant Zero Dependency License: MIT

Industrial-grade Model Context Protocol (MCP) Suite for Personal Longevity, Metabolism, Biomarker Dynamics & Chronobiology. Built with 100% pure Python standard library — Zero external dependencies (pip) required.

🌐 Official Channels

Related MCP server: mcp-tool-framework

🏗️ Architecture & Modules

flowchart TD
    subgraph Client["🤖 Any MCP-Compatible Client"]
        Claude["Claude Desktop / Cursor"]
        SDK["Python / TypeScript MCP SDK"]
    end

    subgraph Core["🧬 genpark-bio-agent (Unified Gateway)"]
        Server["src/genpark_bio/server.py (JSON-RPC 2.0 stdio)"]
        
        subgraph Domains["Physiological Domains"]
            M["metabolic/<br/>Autophagy, Ketones (GKI), MAGE Glycemic"]
            C["cardio_renal/<br/>Hydration (BUN/Cr), Hemodynamics (TPR), BP Dipper"]
            Ch["chronobiology/<br/>DLMO Melatonin, CIE S 026 Lux, Caffeine CYP1A2"]
            N["neuro_recovery/<br/>EEG Spectral Entropy, SpO2 ODI3, Binaural"]
            B["biomechanics/<br/>Cadence Oscillation, Grip Vitality, Spirometry"]
        end
    end

    Client -->|JSON-RPC 2.0| Server
    Server --> Domains

🛠️ MCP Tools Exposed

Tool Name

Domain

Description

estimate_autophagy_index

metabolic

Calculate cellular autophagy & mitophagy onset index from fasting duration and exertion.

calculate_gki_score

metabolic

Compute Glucose-Ketone Index (GKI) longevity ratio from glucose (mg/dL) & BHB (mmol/L).

calculate_mage_glucose_dynamics

metabolic

Compute Mean Amplitude of Glycemic Excursions (MAGE) and glycemic variability from CGM.

calculate_bun_creatinine_ratio

cardio_renal

Assess prerenal azotemia vs intrinsic renal strain from serum BUN and creatinine.

compute_cardiac_output_tpr

cardio_renal

Compute stroke volume (mL), cardiac output (L/min), and total peripheral resistance (TPR).

assess_nocturnal_dipping

cardio_renal

Assess nocturnal blood pressure dipping percentage (Normal, Non-dipper, Reverse dipper).

predict_dlmo_clock_time

chronobiology

Predict Dim Light Melatonin Onset (DLMO) clock time based on wake-up time and evening lux.

calculate_equivalent_melanopic_lux

chronobiology

Calculate CIE S 026 Equivalent Melanopic Lux (EML) for circadian lighting entrainment.

calculate_caffeine_clearance

chronobiology

Model CYP1A2 pharmacokinetic caffeine clearance and bedtime adenosine receptor blockade.

compute_eeg_fatigue_entropy

neuro_recovery

Compute frontal Theta/Beta ratio (TBR) and Shannon spectral entropy for cognitive fatigue.

assess_grip_vitality_age

biomechanics

Score isometric grip strength (kg) against normative cohorts to evaluate biological vitality age.

⚡ 30-Second Quickstart (Zero pip install required)

Run the built-in quickstart demo immediately with standard Python:

python quickstart.py

🔌 Claude Desktop Configuration

Add to your claude_desktop_config.json:

{
  "mcpServers": {
    "genpark-bio": {
      "command": "python",
      "args": ["-m", "genpark_bio.server"]
    }
  }
}

🧪 Self-Test Verification

python -m genpark_bio.server --test

📄 License

MIT License. Copyright (c) 2026 GenPark AI.

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