Search PubMed for biomedical literature.

Searches 34M+ PubMed abstracts using natural language or E-utilities syntax. Returns publication metadata including titles, abstracts, authors, and MeSH terms.

Search PMC for full-text articles.

Searches 7M+ full-text articles in PubMed Central. Unlike PubMed (abstracts only), PMC searches the complete article text.

Search using MeSH controlled vocabulary terms.

MeSH (Medical Subject Headings) provides standardized, hierarchical indexing. Using MeSH ensures consistent retrieval across different terminologies.

Build complex Boolean queries with field-specific search.

Provides precise control over search logic with multiple terms, fields, and Boolean operators.

Search across all NCBI databases to find data availability.

Returns hit counts for 38+ NCBI databases, helping identify which databases have relevant data for your query.

Fetch detailed article summary and metadata.

Returns comprehensive information including title, authors, abstract, MeSH terms, journal details, DOI, and more.

Fetch complete article content.

For PubMed: Returns abstract and metadata (full text not available). For PMC: Returns full text if article is in PMC Open Access.

Fetch article in BioC format for text mining.

BioC provides pre-parsed text ideal for NLP tasks:

• Passage-level segmentation (title, abstract, sections)

• Sentence-level boundaries

• Ready for named entity recognition, relation extraction

Efficiently fetch multiple articles with rate limiting.

Handles large batches by chunking requests and respecting NCBI rate limits. Returns both successful and failed retrievals.

Find articles related to a source article.

Discovers related literature through citation networks and computational similarity.

Find records in other NCBI databases linked to an article.

Maps from literature to biological knowledge bases.

Find all publications by a specific author.

Convert article IDs between different formats.

Supports batch conversion (up to 200 IDs) between:

• PMID (PubMed ID): e.g., "37000000"

• PMCID (PubMed Central ID): e.g., "PMC7611378"

• DOI: e.g., "10.1093/nar/gks1195"

• Manuscript ID: e.g., "NIHMS1677310"

Resolve a single identifier to all available ID formats.

Automatically detects the ID type and returns all available identifiers for the article.

Build and execute a multi-step search pipeline.

Uses Entrez History Server to chain operations efficiently. Ideal for complex queries like: "Find diabetes reviews, then limit to articles linked to HLA genes"

Process large sets of articles with batch operations.

Handles datasets of 10K+ articles efficiently with chunked processing and rate limiting.