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AGR MCP Server

MCP server for querying Alliance of Genome Resources - genomics data across model organisms.

Installation

No installation required. Add to your MCP client config:

{ "mcpServers": { "agr-genomics": { "command": "npx", "args": ["-y", "agr-mcp-server"] } } }

Option 2: Global install

npm install -g agr-mcp-server

Then use in your config:

{ "mcpServers": { "agr-genomics": { "command": "agr-mcp-server" } } }

Config file locations

Client

Config path

Claude Desktop (macOS)

~/Library/Application Support/Claude/claude_desktop_config.json

Claude Desktop (Windows)

%APPDATA%\Claude\claude_desktop_config.json

Claude Code

~/.claude/settings.json

Cursor

Settings > MCP Servers

Windsurf

~/.codeium/windsurf/mcp_config.json

Usage

Ask questions naturally:

  • "Search for BRCA1 genes in human"

  • "What genes are involved in DNA repair?"

  • "Get information about HGNC:1100"

  • "Find orthologs of insulin gene"

  • "What diseases are associated with TP53?"

  • "Show me expression data for daf-2 in worm"

Supported Species

Human, mouse, rat, zebrafish, fly, worm, yeast, xenopus

Tools

Tool

Description

search_genes

Search genes with optional species filter

get_gene_info

Detailed gene information (symbol, location, synonyms)

get_gene_diseases

Disease associations for a gene

search_diseases

Search diseases by name

get_gene_expression

Expression data across tissues/stages

find_orthologs

Cross-species homologs

get_gene_phenotypes

Phenotype annotations

get_gene_interactions

Molecular and genetic interactions

get_gene_alleles

Alleles/variants for a gene

search_alleles

Search alleles by name

get_species_list

List supported model organisms

Gene ID Formats

Species

Format

Example

Human

HGNC:*

HGNC:1100

Mouse

MGI:*

MGI:95892

Rat

RGD:*

RGD:3889

Zebrafish

ZFIN:ZDB-GENE-*

ZFIN:ZDB-GENE-990415-72

Fly

FB:FBgn*

FB:FBgn0000017

Worm

WB:WBGene*

WB:WBGene00000898

Yeast

SGD:S*

SGD:S000002536

Xenopus

Xenbase:XB-GENE-*

Xenbase:XB-GENE-485905

Data Sources

License

MIT

-
security - not tested
F
license - not found
-
quality - not tested

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