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STRING MCP Server

Model Context Protocol (MCP) server providing access to the STRING protein-protein interaction database.

Features

9 tools for protein interaction analysis:

  • Mapping protein identifiers to STRING IDs

  • Retrieving protein interaction networks

  • Finding interaction partners

  • Functional enrichment analysis (GO, KEGG, pathways)

  • PPI enrichment testing

  • Cross-species homology mapping

  • Protein name resolution

Full endpoint documentation available in ENDPOINTS.md.

Installation

From GitHub

npm install git+https://github.com/munch-group/string-mcp.git cd node_modules/string-mcp npm run build

From source

git clone https://github.com/munch-group/string-mcp.git cd string-mcp npm install npm run build

Usage with Claude Desktop

# Using built version claude mcp add string node /path/to/string-mcp/build/index.js # Or from npm global install claude mcp add string npx -y string-mcp

Configuration

Add to your Claude Desktop config:

{ "mcpServers": { "string": { "command": "node", "args": ["/path/to/string-mcp/build/index.js"] } } }

Common Species Taxon IDs

  • Human: 9606

  • Mouse: 10090

  • Rat: 10116

  • Fruit fly: 7227

  • C. elegans: 6239

  • Yeast: 4932

Building

npm run build

Dependencies

  • @mcp/rest-utils - Shared REST utilities

  • @modelcontextprotocol/sdk - MCP SDK

  • zod - Schema validation

License

ISC

-
security - not tested
A
license - permissive license
-
quality - not tested

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