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UniProt MCP Server

by josefdc

Server Configuration

Describes the environment variables required to run the server.

NameRequiredDescriptionDefault
MCP_HTTP_HOSTNoHTTP server bind address0.0.0.0
MCP_HTTP_PORTNoHTTP server port8000
MCP_HTTP_RELOADNoEnable auto-reload: 1 or true0
UNIPROT_LOG_LEVELNoLogging level: debug, info, warning, errorinfo
MCP_HTTP_LOG_LEVELNoUvicorn log levelinfo
UNIPROT_LOG_FORMATNoLog format: plain or jsonplain
UNIPROT_ENABLE_FIELDSNoRequest minimal field subsets to reduce payload size
MCP_CORS_ALLOW_HEADERSNoCORS allowed headers*
MCP_CORS_ALLOW_METHODSNoCORS allowed methodsGET,POST,DELETE
MCP_CORS_ALLOW_ORIGINSNoCORS allowed origins (comma-separated)*
UNIPROT_MAX_CONCURRENCYNoMax concurrent UniProt API requests8

Schema

Prompts

Interactive templates invoked by user choice

NameDescription
summarize_proteinGenerate instructions for summarising a UniProt entry.

Resources

Contextual data attached and managed by the client

NameDescription
search_helpStatic help text explaining search conventions.

Tools

Functions exposed to the LLM to take actions

NameDescription
fetch_entry

Return a structured UniProt entry.

get_sequence

Return only the sequence metadata for an accession.

search_uniprot

Search UniProtKB and return curated hits.

fetch_entry_flatfile

Return the UniProt flatfile (txt or fasta) for a specific entry version.

map_ids

Map identifiers between UniProt-supported namespaces.

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