🏥 NCCN Guidelines MCP Server
A Model Context Protocol (MCP) server that provides access to NCCN (National Comprehensive Cancer Network) clinical guidelines.
🔬 How It Works
This project follows a systematic approach to provide accurate medical guidance:
🧠 Problem Analysis: Understands the clinical question or scenario
📋 Guidelines Retrieval: Searches the NCCN index for relevant guidelines
📄 Page-by-Page Reading: Downloads and extracts specific pages from guidelines
🎯 Evidence-Based Response: Provides answers based on the extracted content
💡 Note: This system does not use RAG (Retrieval-Augmented Generation) to ensure accuracy. Instead, it reads guidelines directly, which may result in longer response times during index initialization and PDF downloading/reading, but provides more reliable and precise medical guidance.
✨ Features
📚 Guidelines Index: Automatically fetches and maintains an up-to-date index of NCCN guidelines
⬇️ PDF Download: Downloads NCCN guideline PDFs with authentication support
📝 Content Extraction: Extracts specific pages from PDF documents with layout preservation
🚀 Smart Caching: Index is cached for 7 days to minimize server load
🛠️ Installation
Clone the repository:
Install dependencies using uv:
⚙️ Configuration
🔧 Configure Client (Note: Supports only agents, such as Cursor, Cline, Claude desktop, etc.)
⚠️ Important: Claude desktop may warn about insufficient context length when running this MCP.
Add this to your Client configuration:
Configuration with Environment Variables
⚠️ Important Notes
👤 NCCN Account Registration: Please note that the NCCN username and password mentioned above must be registered on the official NCCN website.
🚀 First-time Setup: When you first start the MCP server, it needs to generate the YAML index of NCCN guidelines. This process takes 1-2 minutes, so please wait before attempting to use the server.
⏱️ Response Times: Due to the non-RAG approach for accuracy, expect longer response times during guideline downloading and PDF reading processes.
💬 Prompts
To have better response, please add the prompt in the file of prompt.md
to the instruction of your Agent Client before your Question.
🛠️ Available Tools
📊 get_index: Get the raw contents of the NCCN guidelines index YAML file.
📥 download_pdf: Download NCCN guideline PDFs
url
: PDF URL to downloadfilename
(optional): Custom filenameusername
(optional): NCCN login username (defaults to NCCN_USERNAME env var)password
(optional): NCCN login password (defaults to NCCN_PASSWORD env var)
📖 extract_content: Extract content from PDF pages
pdf_path
: Path to PDF filepages
(optional): Comma-separated page numbers (e.g., "1,3,5-7")
💡 Usage Example
Here are some example questions you can ask:
🔬 What are the available first-line immunotherapy options for ES-SCLC?
🎯 What is the initial chemotherapy for triple-negative breast cancer?
🧬 What are the immunotherapy options for neuroendocrine tumors?
A Model Context Protocol server that provides access to National Comprehensive Cancer Network clinical guidelines through direct PDF reading rather than RAG for increased accuracy.
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